IAH Seminar - Effect of voluntary exercise on cognitive and neuropathological changes in a rodent model of diabetes

Location: Great Gable Meeting Room, Clinical Ageing Research Unit, Campus for Ageing and Vitality
Time/Date: 20th September 2012, 12:15 - 13:00

You are invited to the IAH research seminar which will take place on Thursday 20 September 2012 in the Great Gable meeting room of the Clinical Ageing Research Unit. The meeting will start at 12.15 and will be followed at approximately 13.00 by a sandwich lunch.

The presentation today will be given by Dr Richard McQuade (IoN) and Dr Elizabeta Mukaetova-Ladinska (IAH) and the title of their talk will be 'Effect of voluntary exercise on cognitive and neuropathological changes in a rodent model of diabetes'.

Abstract:

Impaired glucose regulation, which is a defining feature of both type 1 and type 2 diabetes, is associated with cognitive impairment in younger individuals and increased risk of dementias in older people. The mechanisms underlying these cognitive impairments are unknown and there are no treatments available.

In studies in mice we have shown that impaired glucose regulation causes spatial memory deficits. We have also shown that aerobic exercise decreases inflammatory proteins and increases synaptic proteins in the brain. We will discuss these findings further regarding their clinical implementation for older adults with diabetes

Published: 13th July 2012