Prof. Doug Turnbull
Professor of Neurology
- Email: D.M.Turnbull@ncl.ac.uk
- Telephone: +44(0)191222 8334
- Fax: +44(0)191 222 8553
- Address: Mitochondrial Research Group
University of Newcastle upon Tyne
The Medical School
Framlington Place
Newcastle uponTyne
NE2 4HH
England
Research Interests
My major research interests are the role of mitochondrial DNA mutations in disease. Mitochondrial DNA disorders are a common group of inborn errors of metabolism and the diagnosis and management of patients with these defects has been a major interest of our group. More recently we have been exploring the role of mitochondrial abnormalities in neurodegenerative disease, ageing and cancer.
Selected Publications
- Whittaker RG; Turnbull DM. A diagnostic tattoo. Clinical Genetics 2009, 75(1), 37-38.
- Fellous TG; McDonald SAC; Burkert J; Humphries A; Islam S; De-Alwis NMW; Gutierrez-Gonzalez L; Tadrous PJ; Elia G; Kocher HM; Bhattacharya S; Mears L; El-Bahrawy M; Turnbull DM; Taylor RW; Greaves LC; Chinnery PF; Day CP; Wright NA; Alison MR. A Methodological Approach to Tracing Cell Lineage in Human Epithelial Tissues. Stem Cells 2009, 27(6), 1410-1420.
- Blakely EL; Trip SA; Swalwell H; He LP; Wren DR; Rich P; Turnbull DM; Omer SE; Taylor RW. A New Mitochondrial Transfer RNA(Pro) Gene Mutation Associated With Myoclonic Epilepsy With Ragged-Red Fibers and Other Neurological Features. Archives of Neurology 2009, 66(3), 399-402.
- Betts-Henderson J; Jaros E; Krishnan KJ; Perry RH; Reeve AK; Schaefer AM; Taylor RW; Turnbull DM. Alpha-synuclein pathology and Parkinsonism associated with POLG1 mutations and multiple mitochondrial DNA deletions. Neuropathology and Applied Neurobiology 2009. 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND: BLACKWELL PUBLISHING, 35(1), 120-124.
- Gutierrez-Gonzalez L; Deheragoda M; Elia G; Leedham SJ; Shankar A; Imber C; Jankowski JA; Turnbull DM; Novelli M; Wright NA; McDonald SA. Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations. J Pathol 2009, 217(4), 489-96.
- McFarland R; Turnbull DM. Batteries not included: diagnosis and management of mitochondrial disease. Journal of Internal Medicine 2009. 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND: BLACKWELL PUBLISHING, 265(2), 210-228.
Qualifications
MBBS (Hons)
MD
PhD
FRCP
