PhD - Newcastle University, UK
BSc(hons) - Hull University, UK
European Association for the Study of Diabetes
My main area of research is aimed at understanding the regulation of glucose metabolism in the pancreatic beta-cell and its relationship to the secretion of insulin by these cells. A significant focus is understanding the cellular regulatory mechanisms of the glucose sensor enzyme glucokinase. Mutations in the glucokinase gene are associated with diabetes (GCK-MODY) and hypoglycaemia. I am using these mutations as a resource to understand the cellular regulation of glucokinase.
Development of novel methods for detecting protein-protein interactions
Expression of glucokinase in other tissues
Glucose-regulated gene expression
I currently co-supervise 3 PhD students and 1 MPhil student.
I currently recieve funding from:
Diabetes Research and Wellness Foundation