Institute of Cellular Medicine

Staff Profile

Dr Christopher Duncan

Clinical Fellow/Honorary Consultant in Infectious Diseases

Background

Roles

  • Clinical Fellowship, Institute of Cellular Medicine, Newcastle University
  • Honorary Consultant in Infectious Diseases, Newcastle upon Tyne Hospitals NHS Foundation Trust 


Previous Positions

  • NIHR Academic Clinical Lecturer in Infectious Diseases, Newcastle University, 2014-2016
  • Specialty Registrar in Infectious Diseases and G(I)M, Northern Deanery, 2013-2017
  • Welcome Trust Research Training Fellowship for Clinicians, University of Oxford 2010-2013
  • Phizackerley Senior Scholarship, Balliol College Oxford 2012-2013
  • Clinical Research Fellow, University of Oxford, 2009-2010
  • Specialty Registrar in Infectious Diseases and G(I)M, West of Scotland Deanery, 2007-2013


Qualifications

  • BMed Sci (1st Class Hons.) University of Aberdeen, 2001
  • MB ChB (Distinction) University of Aberdeen, 2003
  • DPhil University of Oxford, 2014


Professional Responsibilities

  • Sample access committee, Newcastle Academic Health Partners Bioresource
  • Joint Research Scientific Executive Committee
  • Member, Genomics England Clinical Interpretation Partnership (GeCIP)
  • Member: BIA, BSI, NIAAD
  • Peer reviewer (NEJM, BMJ etc.)




Research

Interests

My research aims to define the contribution of innate immunity to the pathogenesis of severe viral disease and immunopathology. I seek mechanistic insight through the detailed analysis of monogenic viral susceptibility variants at the cellular and molecular level, and via targeted genetic perturbation of primary cells with the CRISPR/Cas9 system.

I work closely with Professor Sophie Hambleton's Primary Immunodeficiency Group: http://www.ncl.ac.uk/icm/people/profile/sophie.hambleton 

I have a clinical interest in severe manifestations of viral infection, including in the immunocompromised host.

Funding

  • British Infection Association, Research Fellowship (2017-2018, £70,000)
  • Academy of Medical Sciences, Starter Grant for Clinical Lecturers (2014-2016, £30,000)
  • British Infection Association, Project Grant (2014-2016, £25,000)


Teaching

I am responsible for coordinating Infectious Diseases teaching for the Physician Associate PG Diploma. 

I supervise MRes and PhD students, and welcome enquiries. 

Publications