Dr John Allen
Lead Clinical Scientist / Honorary Lecturer

  • Email: j.allen@ncl.ac.uk
  • Telephone: +44 (0) 191 213 8199
  • Address:

    Microvascular and Clinical Optical Diagnostics,
    Regional Medical Physics Department,
    Freeman Hospital,
    Newcastle upon Tyne
    NE7 7DN
    UK

Background

Senior member of Cardiovascular Physics and Engineering Research Group based at Freeman Hospital, team led by Professor Alan Murray. Affiliated Lecturer in Newcastle University's School of Institute of Cellular Medicine. Main research interests: Cardiovascular Physics and Engineering, and particularly optical and thermal assessments of (micro)vascular disease.

Lead Clinical Scientist with non-ionising radiation focus in NHS.

Roles and Responsibilities

Lead Clinical Scientist, Microvascular and Thermal Diagnostics, Regional Medical Physics Department, Freeman Hospital / RVI, Newcastle upon Tyne.

I have established in Newcastle and manage a unique physiological measurement facility for the assessment of patients with microvascular problems (e.g. Raynaud's phenomenon, connective tissue diseases, diabetes, autonomic dysfunction), working with consultant clinicians in Rheumatology, the Northern Vascular Centre, Falls and Syncope Service, Regional Burns Centre, and Chronic Fatigue and Immunology. State-of-the-art microcirculation assessment facility opened 2009.

Qualifications

PhD Medical Physics, Newcastle University, 2002.

Memberships

Health Professions Council. Registered Clinical Scientist, (1999).

Chartered Scientist (CSci), Science Council.
Chartered Engineer (CEng), Engineering Council.

Electronics specialist group team leader of IEE (now IET) Northumbria Branch Network, 2001 on. Role includes organising the annual lecture programme and specific Branch medical lecture. Lectures for 2004-5 session were "Virtual Reality" and "Surgical Robotics" in 2004/5 session. Have also organised "Nanotechnology in Medicine" and "Forensic Computing" in 2005/6 session, "Optical techniques in Medicine" in 2006/7 session, "Thermal Imaging in Medicine" for 2007/8 session, 2008/9 MRI, and 2009/10 Microwaves and Breast Cancer Detection plus Blood Flow Assessment by Ultrasound. Optical techniques / biophotonics in early cancer detection 21/2/2011 (Prof Nick Stone). I presented the Annual Medical Lecture in January 2012.

Honours and Awards

2009/10 NHS Innovations Awards: Placed 2nd in competition for infrared related invention (May 2010).

The honour to be invited to join the PM at a Reception in Lancaster House in London (2007) - in recognition of those "Delivering excellence in Public Services".

Submitted, on behalf of Cardiovascular Physics and Engineering Research Group, the winning entries for the 2006 NHS Health and Social Care Award for Innovative Technology and the 2007 IPEM Manufacturers' Award.

Awarded Institute of Physics and Engineering in Medicine (IPEM) Travel Bursary to visit hospitals and universities in Cuba, November 2006. Also Visiting Professorship: Biofisica Medica, Santiago de Cuba, Cuba. From 2007.

Awarded Arthritis Research Campaign (ARC) Allied Health Professional Travel Bursary to attend 1st European course on Capillaroscopy, Genoa Italy, September 2004.

 

Languages

Symbolic and situational DNA linkage analysis.

Metaphorical cryptanalysis.

 

Informal Interests

Applying language skills for the good of society. 

 

 

 

Research Interests

1. Microvascular Imaging and Diagnostics: Optical and Thermal based measurements.
2. Multi-site photoplethysmography (PPG) measurements / analysis.
3. Endothelial Function assessments.
4. Raynaud's and Connective Tissue Disease assessment.
5. Pattern Recognition and Fuzzy Logic. 
6. Press release on recent work http://www.rmpd.org.uk/news_and_events/current_news.htm.
 

Other Expertise

Establishing innovative clinical measurement services - the art of risk taking.

Microcirculation assessment using mainly optical techniques, including spectroscopy (NIR, VIS, UV and fluorescence), laser Doppler, photoplethysmography, capillaroscopy, Thermal imaging, near infrared (NIR) imaging, and objective colour measurements.

Digital signal processing of biomedical signals and images, including neural networks and computation, time-frequency analysis, systems identification, spectral analysis and coherence, and computer modelling.

 

Current Work

Currently writing invited Topical Review with Dr Kevin Howell on specific aspects of Microvascular Measurement.

 

Future Research

Collaboration with colleagues from the Institute of Continuous Media Mechanic. Perm, Russia. Salford Hope Hospital Rheumatology Unit. Also with Medical Physics at Universite de Oriente, Santiaga de Cuba.

 

Esteem Indicators

Have contributed to the publication of more than 40 scientific papers and made more than 80 formal scientific presentations to medical and scientific colleagues.

Faculty. 2nd and 3rd European courses on capillaroscopy in rheumatic diseases. Genova Italy, September 2006 and 2008.

External PhD Examiner, Loughborough, Nottingham University and Glamorgan Universities.

External PhD Examiner, Indian Institute of Technology, Madras, India. 

Editorial Board, Physiological Measurement. Institute of Physics Publishing.

Currently working towards Fellow of the Royal Photographic Society (FRPS) - ASIS Imaging Scientist route.

Member, European capillaroscopy analysis group - RSA funded project led by Dr A Herrick, Salford. 

Member, Newcastle University and NuTH Imaging Strategy Group.

 

Funding

Employed as NHS Clinical Scientist.

Grant funding from the Freeman Trustees Charitable Trust and the CFS/ME Northern Network.

Philips Research: Novel neurovascular assessments.

Seeking further funding for various cardiovascular and microvascular research projects. Awarded NIHR FSF funding for 2011/2 to write grant proposals related to cardiovascular and cancer diagnostics.

 

Industrial Relevance

Development of novel cardiovascular techniques for detecting cardiac and vascular disease, mainly using optical and thermal based technologies.

 

Keywords

microvascular 

pulse wave analysis
photoplethysmography
PPG
complex regional pain syndrome
capillaroscopy
thermography
fluorescence
spectroscopy
blood pressure
photomedicine
wound healing
autonomic function
arterial stiffness
cardiovascular
surgical robot
heart rate variability
HRV
amputation
spinal cord stimulation
mirror therapy
ausculatation
percussion
endothelial function
Korotkoff sounds
tissue viability

tilt table
vasomotion
physiological measurement
chronic fatigue syndrome (CFS/ME)
thermal physiology
angiogenesis
microwave thermometry
microcirculation
O2C
British Microcirculation Society
Burn depth
angiogenesis
LDI
Laser Doppler
microwave

Bletchley 

 

Undergraduate Teaching

Faraday Engineer. The Institution of Engineering and Technology (IET).

Newcastle University. Affiliate Lecturer.

Science , Technology, Engineering and Mathematics Ambassador. Northumberland STEMNET.

Postgraduate Teaching

Supervisor for MSc (Modernising Scientific Careers MSc : Non-ionising Radiation module), MRes (project supervision) and MD degrees (projects). Newcastle University.

Medical Physics MSc Curriculum sub-committee.

PhD Supervisor. Biofisica Medica, Santiago de Cuba. Cuba.

Trainee Clinical Scientists.

Clinical Technologists, IPEM. 

Visiting overseas PG students.