Professor John Simpson
Professor of Respiratory Medicine
- Morris AC, Brittan M, Wilkinson TS, McAuley DF, Antonelli J, McCulloch C, Barr LC, McDonald NA, Dhaliwal K, Jones RO, Mackellar A, Haslett C, Hay AW, Swann DG, Anderson N, Laurenson IF, Davidson DJ, Rossi AG, Walsh TS, Simpson AJ. C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients.
Blood 2011, 117(19), 5178-5188.
- ConwayMorris A, Kefala D, Wilkinson TS, Dhaliwal K, Rossi AG, Farrell L, Walsh TS, Mackenzie SJ, Reid H, Davidson DJ, Haslett C, Sallenave JM, Simpson AJ. C5a mediates peripheral blood neutrophil dysfunction in critically ill patients.
American Journal of Respiratory and Critical Care Medicine 2009, 180(1), 19-28.
- Conway Morris A, Kefala K, Wilkinson TS, Moncayo Nieto OL, Dhaliwal K, Farrell L, Walsh TS, Mackenzie SJ, Swann DJ, Andrews PJD, Anderson N, Govan JRW, Laurenson IF, Reid H, Davidson DJ, Haslett C, Sallenave JM, Simpson AJ. Diagnostic importance of pulmonary interleukin-1 beta and interleukin-8 in ventilator-associated pneumonia..
Thorax 2010, 65(3), 201-207.
- Wilkinson TS, Dhaliwal K, Hamilton TW, Lipka AF, Farrell L, Davidson DJ, Duffin R, Haslett C, Govan JRW, Gregory CD, Sallenave JM, Simpson AJ. Trappin-2 promotes early clearance of pseudomonas aeruginosa through CD14-dependent macrophage activiation and neutrophil recruitment.
American Journal of Pathology 2009, 174(4), 1338-1346.
- Lowder BV, Guinane CM, BenZakour NL, Weinert LA, ConwayMorris A, Cartwright RA, Simpson AJ, Rambaut A, Nübel U, Fitzgerald JR. Recent human to poultry host jump, adaptation and pandemic spread of Staphylococcus aureus..
Proceedings of the National Academy of Sciences 2009, 106(46), 19545-19550.
- Murray MP, Govan JRW, Doherty CJ, Simpson AJ, Wilkinson TS, Chalmers JD, Greening AP, Haslett C, Hill AT. A randomised controlled trial of nebulised gentamicin in non-cystic fibrosis bronchiectasis.
American Journal of Respiratory and Critical Care Medicine 2011, 183(4), 491-499.
- Conway Morris A, Kefala K, Simpson AJ, Everingham K, Kerslake D, Raby S, Laurenson IF, Swann DJ, Walsh TS. Evaluation of the effect of diagnostic methodology on the reported incidence of ventilator-associated pneumonia.
Thorax 2009, 64(6), 516-522.
- Brittan M, Barr L, ConwayMorris A, Duffin R, Rossi F, Johnston S, Monro G, Anderson N, Rossi AG, McAuley DF, Haslett C, Hirani N, Dhaliwal K, Simpson AJ. A novel subpopulation of monocyte-like cells in the human lung after LPS inhalation.
European Respiratory Journal 2012, (epub ahead of print).
- MacKinnon AC, Gibbons MA, Farnworth SL, Leffler H, Nilsson UJ, Delaine T, Simpson AJ, Forbes SJ, Hirani N, Gauldie J, Sethi T. Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-3.
American Journal of Respiratory and Critical Care Medicine 2012, 185(5), 537-546.
- Gibbons MA, MacKinnon AC, Ramachandran P, Dhaliwal K, Duffin R, Phythian-Adams AT, Van Rooijen N, Haslett C, Howie SE, Simpson AJ, Hirani N, Gauldie J, Iredale JP, Sethi T, Forbes SJ. Ly6C(hi) Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis.
American Journal of Respiratory and Critical Care Medicine 2011, 184(5), 569-581.
