Professor James Gillespie
Professor of Human Physiology
- Email: james.gillespie@ncl.ac.uk
- Telephone: +44 (0) 191 222 8512
- Address: Oral Biology
School of Dental Sciences
Newcastle University
Newcastle upon Tyne
NE2 4BW
- Nile CJ, Gillespie JI. Interactions Between Cholinergic and Prostaglandin Signaling Elements in the Urothelium: Role for Muscarinic Type 2 Receptors.
Urology 2012, 79(1), 240.e17–240.e23.
- Harvey J, Finney S, Stewart L, Gillespie J. The relationship between cognition and sensation in determining when and where to void: the concept of cognitive voiding.
British Journal of Urology International 2012, (epub ahead of print).
- Grol S, Nile CJ, Martinez-Martinez P, van Koeveringe G, de Wachter S, de Vente J, Gillespie JI. M-3 Muscarinic Receptor-Like Immunoreactivity in Sham Operated and Obstructed Guinea Pig Bladders.
Journal of Urology 2011, 185(5), 1959-1966.
- Biallosterski BT, van Koeveringe GA, van Kerrebroeck PE, Gillespie JI, de Wachter SG. Nonvoiding Activity of the Guinea Pig Bladder.
The Journal of Urology 2011, 186(2), 721-727.
- De Wachter SG, Heeringa R, van Koeveringe GA, Gillespie JI. On the Nature of Bladder Sensation: The Concept of Sensory Modulation.
Neurourology and Urodynamics 2011, 30(7), 1220-1226.
- Grol S, Van Koeveringe GA, De Vente J, Van Kerrebroeck PEV, Gillespie JI. Regional differences in sensory innervation and suburothelial interstitial cells in the bladder neck and urethra.
BJU International 2008, 102(7), 870-877.
- Finney SM, Stewart LH, Gillespie JI. Volume-induced responses in the isolated bladder: evidence for excitatory and inhibitory elements.
BJU International 2008, 102(9), 1154-1161.
- De Jongh R, Van Koeveringe GA, Van Kerrebroeck PEV, Markerink-Van Ittersum M, De Vente J, Gillespie JI. Alterations to network of NO/cGMP-responsive interstitial cells induced by outlet obstruction in guinea-pig bladder.
Cell and Tissue Research 2007, 330(1), 147-160.
- de Vente J, Ittersum MMV, Gillespie JI. Natriuretic peptide responsive, cyclic guanosine monophosphate producing structures in the guinea pig bladder.
Journal of Urology 2007, 177(3), 1191-1194.
- Lagou M, Gillespie JI, Andersson K-E, Kirkwood T, Drake MJ. Bladder volume alters cholinergic responses of the isolated whole mouse bladder.
Journal of Urology 2006, 175(2), 771-776.
- Gillespie JI, Markerink-Van Ittersum M, De Vente J. Endogenous nitric oxide/cGMP signalling in the guinea pig bladder: Evidence for distinct populations of sub-urothelial interstitial cells.
Cell and Tissue Research 2006, 325(2), 325-332.
- Gillespie JI, Markerink-Van Ittersum M, De Vente J. Interstitial cells and cholinergic signalling in the outer muscle layers of the guinea-pig bladder.
BJU International 2006, 97(2), 379-385.
- Lagou M, Drake MJ, Markerink-Van Ittersum M, De Vente J, Gillespie JI. Interstitial cells and phasic activity in the isolated mouse bladder.
BJU International 2006, 98(3), 643-650.
- Lagou M, Gillespie J, Kirkwood T, Harvey I, Drake MJ. Muscarinic stimulation of the mouse isolated whole bladder: Physiological responses in young and ageing mice.
Autonomic and Autacoid Pharmacology 2006, 26(3), 253-260.
- Streng T, Hedlund P, Talo A, Andersson K-E, Gillespie JI. Phasic non-micturition contractions in the bladder of the anaesthetized and awake rat.
BJU International 2006, 97(5), 1094-1101.
- Gillespie JI, Markerink-Van Ittersum M, De Vente J. Sensory collaterals, intramural ganglia and motor nerves in the guinea-pig bladder: Evidence for intramural neural circuits.
Cell and Tissue Research 2006, 325(1), 33-45.
- Gillespie JI. The Autonomous Bladder: A View of the Origin of Bladder Overactivity and Sensory Urge.
BJU International 2006, 93(4), 478-483.
- Gillespie JI. Animal Models of Urge Incontinence: An evolving view of the origins of bladder overactivity and sensory urge.
BJU International 2005,96 s1 22-28.
- Gillespie JI, Markerink-van Ittersum M, De Vente J. Expression of neuronal nitric oxide synthase (nNOS) and nitric-oxide-induced changes in cGMP in the urothelial layer of the guinea pig bladder.
Cell and Tissue Research 2005,321 3 341-351.
- Gillespie JI. Inhibitory actions of calcitonin gene-related peptide and capsaicin: Evidence for local axonal reflexes in the bladder wall.
BJU International 2005,95 1 149-156.
- Drake MJ, Harvey IJ, Gillespie JI, Van Duyl WA. Localized contractions in the normal human bladder and in urinary urgency.
BJU International 2005, 95(7), 1002-1005.
- Gillespie JI, Markerink-Van Ittersum M, De Vente J. cGMP-generating cells in the bladder wall: Identification of distinct networks of interstitial cells.
BJU International 2004,94 7 1114-1124.
- Galvin DJ, Watson RWG, O'Neill A, Coffey RNT, Taylor C, Gillespie JI, Fitzpatrick JM. Hypoxia inhibits human bladder smooth muscle cell proliferation: A potential mechanism of bladder dysfunction.
Neurourology and Urodynamics 2004,23 4 342-348.
- Gillespie JI. Modulation of autonomous contractile activity in the isolated whole bladder of the guinea pig.
BJU International 2004,93 3 393-400.
- Gillespie JI. Noradrenaline inhibits autonomous activity in the isolated guinea pig bladder.
BJU International 2004,93 3 401-409.
- Gillespie JI. Phosphodiesterase-linked inhibition of nonmicturition activity in the isolated bladder.
BJU International 2004, 93(9), 1325-1332.
- Gillespie JI, Drake MJ. The actions of sodium nitroprusside and the phosphodiesterase inhibitor dipyriclamole on phasic activity in the isolated guinea-pig bladder.
BJU International 2004, 93(6), 851-858.
- Lagou M, Drake MJ, Gillespie JI. Volume-induced effects on the isolated bladder: A possible local reflex.
BJU International 2004, 94(9), 1356-1365.
- Drake MJ, Harvey IJ, Gillespie JI. Autonomous activity in the isolated guinea pig bladder.
Experimental Physiology 2003. ,88 1 19-30.
- Drake MJ, Hedlund P, Harvey IJ, Pandita RK, Andersson K-E, Gillespie JI. Partial outlet obstruction enhances modular autonomous activity in the isolated rat bladder.
Journal of Urology 2003,170 1 276-279.
- Hansrani M, Gillespie JI, Stansby G. Homocysteine in myointimal hyperplasia.
European Journal of Vascular and Endovascular Surgery 2002, 23(1), 3-10.
- Hansrani M, Gillespie JI, Stansby G. Homocysteine in myointimal hyperplasia.
European Journal of Vascular and Endovascular Surgery 2002, 23(1), 3-10.
- Fry CH, Sui GP, Coppen SR, Dupont E, Rothery S, Newgreen D, Gillespie JI, Severs NJ. Intracellular resistance and connexin expression in stable and unstable human bladder smooth muscle.
In: Journal of Physiology: Conference of the Physiological Society. 2002, Liverpool: Wiley-Blackwell Publishing Ltd.
- Galvin DJ, Watson RWG, Gillespie JI, Brady H, Fitzpatrick JM. Mechanical stretch regulates cell survival in human bladder smooth muscle cells in vitro.
American Journal of Physiology: Renal Physiology 2002, 283(6), F1192-F1199.
- Lu XM, Boudouin SV, Gillespie JI. Vascular smooth muscle alpha-actin is expressed in HUVECs and could be a potential marker for circulating endothelial cells [abstract].
Arteriosclerosis, Thrombosis, and Vascular Biology 2002, 22(5), A65 abstract no. P370.
- Mutunga M, Fulton B, Bullock R, Batchelor A, Gascoigne A, Gillespie JI, Baudouin SV. Circulating endothelial cells in patients with septic shock.
American Journal of Respiratory and Critical Care Medicine 2001, 163(1), 195-200.
- Lu X, Chishti A, Fulton B, Bullock R, Batchelor A, Gascoigne A, Gillespie JI, Baudouin SV. Circulating endothelial progenitor cells in human sepsis.
In: British Journal of Anaesthesia. 2001, Oxford University Press.
- Drake MJ, Mills IW, Gillespie JI. Model of peripheral autonomous modules and a myovesical plexus in normal and overactive bladder function.
Lancet 2001, 358(9279), 401-403.
- Berger CEM, Rathod H, Gillespie JI, Horrocks BR, Datta HK. Scanning electrochemical microscopy at the surface of bone-resorbing osteoclasts: Evidence for steady-state disposal and intracellular functional compartmentalization of calcium.
Journal of Bone and Mineral Research 2001, 16(11), 2092-2102.
- Hardy LA, Harvey IJ, Chambers P, Gillespie JI. A putative alternatively spliced variant of the P2X1 purinoreceptor in human bladder.
Experimental Physiology 2000, 85(4), 461-463.
- Tanner R, Chambers P, Khadra MH, Gillespie JI. The production of nerve growth factor by human bladder smooth muscle cells in vivo and in vitro.
BJU International 2000, 85(9), 1115-1119.
- Hatthachote P, Gillespie JI. Complex interactions between sex steroids and cytokines in the human pregnant myometrium: Evidence for an autocrine signaling system at term.
Endocrinology 1999, 140(6), 2533-2540.
- Masters JG, Neal DE, Gillespie JI. Contractions in human detrusor smooth muscle induced by hypo-osmolar solutions.
Journal of Urology 1999, 162(2), 581-589.
- R. G. Charlton, A. R. Morley, P. Chambers and J. I. Gillespie. Focal changes in nerve, muscle and connective tissue in normal and unstable human bladder.
Bju International 1999, 84, 953-960.
- P. Chambers, D. E. Neal and J. I. Gillespie. Ryanodine receptors in human bladder smooth muscle.
Experimental Physiology 1999, 84, 41-46.
- Gillespie JI, Masters JG and Neal DE. The contribution of intracellular Ca2+ release to contraction in human bladder smooth muscle.
British Journal of Pharmacology 1999, 127, 996-1002.
- P. Chambers, D. E. Neal and J. I. Gillespie. The expression of heterotrimeric G-proteins in human bladder smooth muscle.
Journal of Urology 1998, 159, 96.
