Dr Malcolm Brodlie
Academic Clinical Lecturer in Paediatric Respiratory Medicine

  • Email: malcolm.brodlie@ncl.ac.uk
  • Telephone: 0191 2336161 Dect 21752
  • Address: c/o Paediatric Respiratory Secretaries
    Old Children's Outpatients Department
    Royal Victoria Infirmary
    Newcastle upon Tyne
    United Kingdom
    NE1 4LP

Introduction 

I am an Academic Clinical Lecturer in Paediatric Respiratory Medicine at the Institute of Cellular Medicine, Newcastle University and an Honorary SpR in Paediatric Respiratory Medicine at the Great North Children’s Hospital, Newcastle upon Tyne. 

Qualifications

BSc (Hons), MB ChB, MRCPCH, PhD

Roles and responsibilities

  •  Member British Paediatric Respiratory Society Executive Committee, trainee representative
  •  Member RCPCH Paediatric Respiratory Medicine CSAC, trainee representative
  •  Organiser of Regional Paediatric Respiratory Medicine CPD meetings

 Awards

  •  Wellcome Trust Elective Prize, 2000
  •  Joint Medical Research Council/Cystic Fibrosis Trust Clinical Research Training Fellowship, 2008
  •  Best oral presentation: Northern Paediatric Research and Development Conference, 2008
  •  British Lung Foundation Travel Fellowship, 2008
  •  Cystic Fibrosis Trust Travel Award, 2009
  •  Best poster: Institute of Cellular Medicine and Institute of Ageing and Health Research Day, 2009
  •  Best oral presentation: Academic Paediatrics Association, 2009
  •  Medical Research Council, supplementary travel award, 2010
  •  European Respiratory Society Bursary for the 8th ERS Lung Science Conference, 2010
  •  British Paediatric Respiratory Society Travel Award, European Cystic Fibrosis Society Conference, 2012

 

Research interests 

  • Translational cystic fibrosis research
  • Techniques for primary airway epithelial cell culture
  • Investigation of the mechanisms of neutrophilic inflammation, airway remodelling and dendritic-epithelial  cell interactions in CF lung disease
  • Aspiration
  • Clinical paediatric respiratory medicine research, including severe asthma, lung transplantation and cough

Funding

  • April 2012: 'Mucus permeating nanoparticulate drug delivery systems' Project Alexander EU FP7. €15.5 million (with Prof JP Pearson, Newcastle University split €830,000)
  • Dec 2011: ‘Functional characterisation and pharmacological manipulation of airway sphingolipids in cystic fibrosis’ Wellcome Trust/Academy of Medical Sciences: £29,921.60
  • Nov 2011: ‘Functional characterisation and pharmacological manipulation of airway sphingolipids in cystic fibrosis’ Newcastle upon Tyne Hospitals NHS Charity (the Trustees): £24,352.10
  • Nov 2011: FSF funding for Dr Jane Falconer, post-doctoral researcher salary. Newcastle upon Tyne Hospitals NHS Foundation Trust: £12,095
  • Apr 2009: ‘Investigating epithelial cell and dendritic cell interactions in cystic fibrosis’ Newcastle Hospitals Special Trustees: £50,000
  • Jun 2008 ‘The culture of primary bronchial epithelial cells from cystic fibrosis lungs – a model to investigate the role of Interleukin-17 in cystic fibrosis lung disease’ Inaugural recipient of the only personal Joint Medical Research Council/Cystic Fibrosis Trust Research Training Fellowship: £132,084
  • Mar 2007 ‘An investigation in to the role of interleukin-17 in cystic fibrosis lung disease’ Newcastle Hospitals Special Trustees: £50,000