Newcastle University

Introduction

Consultant Physicist & Head of Physiological Measurement with the Regional Medical Physics Department, Newcastle upon Tyne Hospitals.

RESEARCH INTERESTS

Clinical instrumentation, particularly for minimally invasive assessment and diagnosis. Acquisition and digital processing of physiological signals.

Particular areas of clinical interest are:

Sleep:  Long-term monitoring of physiological function, and assessment of polygraphic data for understanding the mechanisms of snoring and obstructive sleep apnoea.

Urodynamics:  Minimally invasive urodynamics, uroflowmetry and non-invasive pressure measurements.

ENT:  Instrumentation for dysphagia & voice disorders; snoring & obstructive sleep apnoea.

Critical care physics: Remote monitoring of intra-cranial pressure and other physiological vital signs.
 

CURRENT WORK

The Peepod: A take-home uroflowmeter for men. Project funded by the Wellcome Trust.

Spectrophotometer: An instrument for measurement of oxygen saturation from non-pulsatile tissue.

Brain compliance probe: For measuring the volume compliance of the human brain in patients following craniectomy.

Pupilometer: For real-time measurement of pupil reaction to light. Credit for the idea to Andy Clark and Iain Chambers.

Neonatal haemodialyser: Redevelopment of an instrument for dialysing extremely small babies. Credit for the idea goes to Malcolm Coulthard and Jean Crosier, from paediatric nephrology at the RVI.

The cuff machine: Ongoing development of an instrument for the non-invasive assessment of bladder pressure in men. Credit for the orignial instrument to Clive Griffiths.
 

OTHER THINGS

Some medical statistics, mostly through trial and error.

Schools outreach work for the Teacher/Scientist Network, Scientists@Work, The Institute of Physics, and STEMnet. 

POSTGRADUATE TEACHING

 Current module leader for:

• Modernising Scientific Careers Physiological Sciences (Urodynamics) 
• Modernising Scientific Careers Physiological Sciences (GI science)
• Modernising Scientific Careers Medical Physics (Clinical Engineering)

Previous degree program director for:

• MSC dysphgia dysphonia research

Previous module leader for:

• MSC dysphgia dysphonia research (Research Design)
• MRes Molecular Biosciences (Clinical Measurement)
• Modernising Scientific Careers Medical Physics (Clinical Engineering)

POSTGRADUATE SUPERVISION

Currently supervising 2 PhDs in the Medical School. 

• Clarkson B, Robson W, Griffiths C, McArdle F, Pickard R, Drinnan M. Continuous non-invasive measurement of bladder voiding pressure using an experimental constant low flow test. Neurourology and Urodynamics 2012, (epub ahead of print).
• Kumar R, Drinnan M, Mehanna H, Paleri V. Efficacy of the two week wait referral system for head and neck cancer: A systematic review. The Annals of The Royal College of Surgeons of England 2012, 94(3), 101-105.
• Bray A, Griffiths C, Drinnan M, Pickard R. Methods and value of home uroflowmetry in the assessment of men with lower urinary tract symptoms: A literature review. Neurourology and Urodynamics 2012, 31(1), 7-12.
• Thomas L, Drinnan M, Basavaiah N, Mehanna H, Jones T, Paleri V. Open conservation partial laryngectomy for laryngeal cancer: A Systematic review of English language literature. Cancer Treatment Reviews 2012, 38(3), 203-211.
• Paleri V, Carding P, Drinnan M, Kelly C, Welch AR, Wilson JA. Voice outcomes following concurrent Chemoradiotherapy for advanced non-laryngeal head and neck cancer: a prospective study. Head and Neck 2012, (epub ahead of print).
• Paleri V, Thomas L, Basavaiah N, Drinnan M, Mehanna H, Jones T. Oncological outcomes of open conservation laryngectomy for radiorecurrent laryngeal carcinoma: A systematic review and meta-analysis of English language literature. Cancer 2011, 117(12), 2668-2676.
• Brockmann M, Drinnan MJ, Storck C, Carding P. Reliable jitter and shimmer measurements in voice clinics: the relevance of vowel, gender, vocal intensity and fundamental frequency effects in a typical clinical task. Journal of Voice 2011, 25(1), 44-53.
• Brockmann M, Drinnan MJ. Routine acoustic voice analysis: time to think again?. Current Opinion in Otolaryngology and Head & Neck Surgery 2011, 19(3), 165-170.
• Cathcart RA, Hamilton DW, Drinnan MJ, Gibson GJ, Wilson JA. Night to night variation in snoring sound severity: one night studies are not enough. Clinical Otolaryngology 2010, 35(3), 198-203.
• Haselden K, Powell T, Drinnan M, Carding P. Comparing Health Locus of Control in Patients with Spasmodic Dysphonia, Functional Dysphonia and Nonlaryngeal Dystonia. Journal of Voice 2009, 23(6), 699-706.
• McArdle F, Clarkson B, Robson W, Griffiths C, Drinnan MJ, Pickard R. Interobserver agreement for noninvasive bladder pressure flow recording with penile cuff. Journal of Urology 2009, 182(5), 2397-2403.
• Harding C, Robson W, Drinnan M, McIntosh S, Sajeel M, Giffiths C, Pickard R. The penile cuff test: A clinically useful non-invasive urodynamic investigation to diagnose men with lower urinary tract symptoms. Indian Journal of Urology 2009, 25(1), 116-121.
• Caffarel J, Griffiths C, Pickard R, Robson W, Drinnan MJ. The questionable benefit of multiple free-flow studies in men with lower urinary tract symptoms. Neurourology and Urodynamics 2009, 28(3), 263-264.
• Evans E, Carding P, Drinnan MJ. The Vocal Handicap Index with post-laryngectomy voices. International Journal of Language and Communication Disorders 2009, 44(5), 575-586.
• Caffarel J, Griffiths C, Pickard R, Robson W, Drinnan M. Modeling the clinical assessment of men with suspected obstructed voiding using Bayes' Theorem. Neurourology and Urodynamics 2008, 27(8), 797-801.
• Clarkson B, Robson W, Griffiths C, McArdle F, Drinnan M, Pickard R. Multisite Evaluation of Noninvasive Bladder Pressure Flow Recording Using the Penile Cuff Device: Assessment of Test-Retest Agreement. Journal of Urology 2008, 180(6), 2515-2521.
• Dyer JC, Leslie P, Drinnan MJ. Objective computer-based assessment of valleculae residue - Is it useful?. Dysphagia 2008, 23(1), 7-15.
• Dyer J, Leslie P, Drinnan MJ. Objective Computer-Based Assessment of Valleculae Residue – Is It Useful?. Dysphagia 2008, 23(1), 7-15.
• Buswell CA, Leslie P, Embleton ND, Drinnan MJ. Oral-motor Dysfunction at 10 Months Corrected Gestational Age in Infants Born Less Than 37 Weeks Preterm. Dysphagia 2008, 24(1), 20-25.
• Kelly A, Macfarlane K, Ghufoor K, Drinnan MJ, Lew-Gor S. Pharyngeal residue across the lifespan; a first look at what’s normal. Clinical Otolaryngology 2008, 33(4), 348-351.
• Hales PA, Drinnan MJ, Wilson JA. The added value of fibreoptic endoscopic evaluation of swallowing in tracheostomy weaning. Clinical Otolaryngology 2008, 33(4), 319-24.
• Kelly A, Drinnan MJ, Savy L, Howard DJ. Total laryngo-pharyngo-oesophagectomy with gastric transposition reconstruction: a review of long-term swallowing outcomes. Journal of Laryngology & Otology 2008, 122(12), 1354-1359.
• Brockmann M, Carding P, Storck C, Drinnan MJ. Voice Loudness and Gender Effects on Jitter and Shimmer in Healthy Adults. Journal of Speech and Hearing Research 2008, 51, 1152-1160.
• Drinnan M, Clarkson B, Robson W, Harding C, Caffarel J, Pickard R, Griffiths C. A new nomogram for the penile cuff study. Neurourology and Urodynamics 2007, 26(5), 624-626.
• Bateman C, Leslie P, Drinnan MJ. Adult Dysphagia Assessment in the UK and Ireland: Are SLTs Assessing the Same Factors?. Dysphagia 2007, 22(3), 174-186.
• Bateman C, Leslie P, Drinnan MJ. Adult Dysphagia Assessment in the UK and Ireland: Are SLTs Assessing the Same Factors?. Dysphagia 2007, 22(3), 174-186.
• Kelly A, Drinnan MJ, Leslie P. Assessing penetration and aspiration: how do videofluoroscopy and FEES compare?. Laryngoscope 2007, 117(10), 1723-1727.
• Sajeel M, Harding C, Robson W, Drinnan M, Griffiths C, Pickard R. Categorisation of Obstruction Using Noninvasive Pressure Flow Measurements: Sensitivity to Change Following Prostatectomy. Journal of Urology 2007, 178(3), 996-1001.
• Leslie P, Drinnan MJ, Zammit-Maempel I, Coyle JL, Ford GA, Wilson JA. Cervical auscultation synchronized with images from endoscopy swallow evaluations. Dysphagia 2007, 22(4), 290-298.
• Daniilidou P, Carding P, Wilson JA, Drinnan MJ, Deary V. Cognitive behavioral therapy for functional dysphonia: A pilot study. Annals of Otology, Rhinology and Laryngology 2007, 116(10), 717-722.
• Gamberini L, Carding PN, Drinnan M. Comparing two models of voice care delivery. Clinical Otolaryngology 2007, 32(2), 122-125.
• Gamberini LJ, Carding PN, Drinnan MJ. Comparing two models of voice care delivery. Clinical Otolaryngology 2007, 32(2), 122-125.
• Crawford H, Leslie P, Drinnan MJ. Compliance with Dysphagia Recommendations by Carers of Adults with Intellectual Impairment. Dysphagia 2007, 22(4), 326-334.
• Caffarel J, Robson W, Pickard R, Griffiths C, Drinnan M. Flow measurements: Can several "wrongs" make a "right"?. Neurourology and Urodynamics 2007, 26(4), 474-480.
• Anari S, Carding PN, Hawthorne MR, Deakin J, Drinnan MJ. Nonpharmacologic effects of botulinum toxin on the life quality of patients with spasmodic dysphonia. Laryngoscope 2007, 117(10), 1888-1892.
• Roe JWG, Leslie P, Drinnan MJ. Oropharyngeal dysphagia: the experience of patients with non-head and neck cancers receiving specialist palliative care. Palliative Medicine 2007, 21(7), 567-574.
• Harding C, Robson W, Drinnan M, Sajeel M, Ramsden P, Griffiths C, Pickard R. Predicting the Outcome of Prostatectomy Using Noninvasive Bladder Pressure and Urine Flow Measurements. European Urology 2007, 52(1), 186-192.
• Fletcher HA, Drinnan MJ, Carding PN. Voice care knowledge among clinicians and people with healthy voices or dysphonia. Journal of Voice 2007, 21(1), 80-91.
• Fletcher HM, Drinnan MJ, Carding PN. Voice care knowledge of clinicians, dysphonics and healthy voices. Journal of Voice 2007, 21(1), 80-91.
• Buck F, Drinnan M, Wilson J, Barnard IS. What are the illness perceptions of people with dysphonia: A pilot study. Journal of Laryngology and Otology 2007, 121(1), 31-39.
• Drinnan MJ, Robson WA, Caffarel J, Pickard RS, McIntosh SL, Harding C, Griffiths CJ. Basic principles of the Newcastle penile cuff test. Urodinamica 2006, 16, 289-297.
• Caffarel J, Gibson GJ, Harrison P, Griffiths CJ, Drinnan MJ. Comparison of manual sleep staging with automated neural network-based analysis in clinical practice. Medical and Biological Engineering & Computing 2006, 44(1-2), 105-110.
• Caffarel J, Gibson GJ, Harrison JP, Griffiths CJ, Drinnan MJ. Comparison of manual sleep staging with automated neural network-based analysis in clinical practice. Medical and Biological Engineering and Computing 2006, 44(1-2), 105-110.
• Macdonald A, Drinnan M, Johnston A, Reda M, Griffiths C, Wilson J, Gibson GJ. Evaluation of potential predictors of outcome of laser-assisted uvulopalatoplasty for snoring. Otolaryngology: Head and Neck Surgery 2006, 134(2), 197-203.
• Jones SM, Carding PN, Drinnan MJ. Exploring the relationship between severity of dysphonia and voice-related quality of life. Clinical Otolaryngology 2006, 31(5), 411-417.
• Kelly AM, Leslie P, Beale T, Payten C, Drinnan MJ. Fibreoptic endoscopic evaluation of swallowing and videofluoroscopy: Does examination type influence perception of pharyngeal residue severity?. Clinical Otolaryngology 2006, 31(5), 425-432.
• Caffarel J, Griffiths CJ, Pickard RS, Robson WA, Drinnan MJ. Flow - how far can you go?. Urodinamica 2006, 16, 259-269.
• Douglas SA, Webster S, El Badawey MR, Drinnan M, Matthews JNS, Gibson GJ, Wilson JA. The development of a snoring symptoms inventory. Otolaryngology - Head and Neck Surgery 2006, 134(1), 56-62.
• Gillivan-Murphy P, Drinnan M, O'Dwyer T, Ridha H, Carding P. The Effectiveness of a Voice Treatment Approach for Teachers With Self-Reported Voice Problems. Journal of Voice 2006, 20(3), 423-431.
• Pickard R, Harding C, Robson W, McIntosh S, Sajeel M, Ramsden P, Drinnan M, Griffiths C. The role of non-invasive bladder pressure measurement by the penile cuff device for assessment of men with lower urinary tract symptoms. Urodinamica 2006, 16, 298-309.
• Harding CK, Robson W, Drinnan MJ, Ramsden PD, Griffiths C, Pickard RS. Variation in Invasive and Noninvasive Measurements of Isovolumetric Bladder Pressure and Categorization of Obstruction According to Bladder Volume. Journal of Urology 2006, 176(1), 172-176.
• Griffiths CJ, Harding C, Blake C, McIntosh S, Drinnan MJ, Robson WA, Abrams P, Ramsden PD, Pickard RS. A nomogram to classify men with lower urinary tract symptoms using urine flow and noninvasive measurement of bladder pressure. Journal of Urology 2005, 174(4 pt.1), 1323-1326.
• Leslie P, Drinnan M, Ford G, Wilson J. Swallow respiratory patterns and aging: Presbyphagia or dysphagia?. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences 2005, 60(3), 391-395.
• Lee M, Drinnan M, Carding P. The reliability and validity of patient self-rating of their own voice quality. Clinical Otolaryngology 2005, 30(4), 357-361.
• Harding CK, Robson W, Drinnan MJ, Griffiths CJ, Ramsden PD, Pickard RS. An automated penile compression release maneuver as a noninvasive test for diagnosis of bladder outlet obstruction. Journal of Urology 2004,172 6 (Part 1) 2312-2315.
• Robinson HR, Drinnan MJ, Carding PN. Laryngeal function therapy for patients with a unilateral vocal fold paralysis. Journal of Laryngology and Otology 2004, (submitted).
• McIntosh SL, Drinnan MJ, Griffiths CJ, Robson WA, Ramsden PD, Pickard RS. Noninvasive assessment of bladder contractility in men. Journal of Urology 2004,172 4 I 1394-1398.
• Leslie P, Drinnan MJ, Finn P, Ford GA, Wilson JA. Reliability and validity of cervical auscultation: A controlled comparison using videofluoroscopy. Dysphagia 2004, 19(4), 231-240.
• Drinnan MJ, Anderson R, Wilson JA, Reda M, Gibson GJ. The effect of posture and sleep stage on snoring sound level. In: Winter Meeting of the British Thoracic Society. 2004, London: Thorax: BMJ Publishing Group.
• Mathias T, Drinnan MJ, Carding PN. The effects of two realy vocal care programmes on patients with dysphonia. Journal of Voice 2004, (in preparation).
• Langley P, Bowers EJ, Brown N, Wild J, Drinnan MJ, Allen J, Sims AJ, Murray A. An algorithm to distinguish ischemic and non-ischaemic ST changes in the Holter ECG. In: Computers in Cardiology Meeting. 2003, Thessaloniki, Greece: IEEE.
• Drinnan MJ, Pickard RS, Ramsden PD, Griffiths CJ. Assessment of prostatic obstruction: A cuff may be enough. Neurourology and Urodynamics 2003,22 1 40-43.
• Drinnan MJ, McIntosh SL, Robson WA, Pickard RS, Ramsden PD, Griffiths CJ. Inter-observer agreement in the estimation of bladder pressure using a penile cuff. Neurourology and Urodynamics 2003,22 4 296-300.
• McIntosh SL, Griffiths CJ, Drinnan MJ, Robson WA, Ramsden PD, Pickard RS. Noninvasive measurement of bladder pressure. Does mechanical interruption of the urinary stream inhibit detrusor contraction?. Journal of Urology 2003,169 3 1003-1006.
• McIntosh S, Drinnan M, Griffiths C, Robson W, Ramsden P, Pickard R. Relationship of abdominal pressure and body mass index in men with LUTS. Neurourology and Urodynamics 2003,22 6 602-605.
• Griffiths CJ, Rix D, Macdonald A, Drinnan MJ, Pickard RS, Ramsden PD. Non-invasive measurement of bladder pressure using controlled inflation of a penile cuff: comparison with simultaneous invasive measurements in patients and volunteers. Journal of Urology 2002, 167(3), 1344-1347.
• Griffiths CJ, Rix D, MacDonald AM, Drinnan MJ, Pickard RS, Ramsden PD. Noninvasive measurement of bladder pressure by controlled inflation of a penile cuff. Journal of Urology 2002, 167(3), 1344-1347.
• Leslie P, Drinnan MJ, Ford GA, Wilson JA. Resting respiration in dysphagic patients following acute stroke. Dysphagia 2002,17 3 208-213.
• Leslie P, Drinnan MJ, Ford GA, Wilson JA. Swallow respiration patterns in dysphagic patients following acute stroke. Dysphagia 2002,17 3 202-207.
• Drinnan MJ, MacDonald AM, Reda M, Wilson JA, Gibson GJ. The effect of recording site in acoustic analysis of snoring. In: Thorax: Winter Meeting of the British Thoracic Society. 2002, London: BMJ Group.
• Drinnan MJ, Allen J, Murray A. Relation between heart rate and pulse transit time during paced respiration. Physiological Measurement 2001, 22(3), 425-432.
• Drinnan MJ, Robson W, Reddy M, Pickard RS, Ramsden PD, Griffiths CJ. Transmission of penile cuff pressure to the penile urethra. Journal of Urology 2001, 166(6), 2545-2549.
• Drinnan MJ, Allen J, Langley P, Murray A. Detection of sleep apnoea from frequency analysis of heart rate variability. In: Computers in Cardiology 2000. 2000, Cambridge, MA, USA: Institution of Electronic and Electrical Engineers.
• M.J. Drinnan,H.C. Richardson,P.R. Close,A.J. Smithson,J.E.S. White,C.J. Griffiths,H.F. Marshall,G.J. Gibson. Objective benefit of laser palatoplasty for non-apnoeic snoring. Clinical Otolaryngology 1999, 24, 335-338.
• H.C. Richardson,M.J. Drinnan,P.R. Close,J.E.S. White,C.J. Griffiths,G.J. Gibson. Psychometric performance before and after laser palatoplasty for nonapnoeic snoring. Clinical Otolaryngology 1999, 24, 339-342.
• M.J. Drinnan,A. Murray,C.J. Griffiths,G.J. Gibson. Inter-observer variability in recognising arousal in respiratory sleep disorders. American Journal of Respiratory & Critical Care Medicine 1998, 158, 358-362.
• M. J. Drinnan, A. Murray, C. J. Griffiths and G. J. Gibson. Interobserver variability in recognizing arousal in respiratory sleep disorders. American Journal of Respiratory and Critical Care Medicine 1998, 158, 358-362.
• M.J. Drinnan,A. Murray,J.E.S. White,A.J. Smithson,C.J. Griffiths,G.J. Gibson. Automated recognition of EEG changes accompanying arousal in respiratory sleep disorders. Sleep 1996, 19, 296-303.
• M.J. Drinnan,A. Murray,J.E.S. White,A.J. Smithson,C.J. Griffiths,G.J. Gibson. Evaluation of activity-based techniques to identify transient arousal in respiratory sleep disorders. Journal of Sleep Research 1996, 5, 173-180.
• A.J. Smithson,J.E.S. White,C.J. Griffiths,A.J. Prichard,P.R. Close,M.J. Drinnan,H.F. Marshall,G.J. Gibson. Comparison of methods for assessing snoring. Clinical Otolaryngology 1995, 20, 443-447.
• A.J. Prichard,A.J. Smithson,J.E.S. White,P.R. Close,M.J. Drinnan,C.J. Griffiths,H.F. Marshall,G.J. Gibson. Objective measurement of the results of uvulopalatopharyngoplasty for snoring. Clinical Otolaryngology 1995, 20, 495-498.
• J.E.S. White,M.J. Drinnan,A.J. Smithson,C.J. Griffiths,G.J. Gibson. Respiratory muscle activity and oxygenation during sleep in patients with muscle weakness. European Respiratory Journal 1995, 8, 807-814.
• J.E.S. White,M.J. Drinnan,A.J. Smithson,C.J. Griffiths,G.J. Gibson. Respiratory muscle activity during rapid-eye-movement (REM) sleep in patients with chronic obstructive pulmonary disease. Thorax 1995, 50, 376-382.
• M.J. Drinnan,A. Murray,J.E.S. White,A.J. Smithson,C.J. Griffiths,G.J. Gibson. Automated measurement of the cyclic activity of respiratory muscles. Medical Engineering & Physics 1994, 16, 477-483.
• J.E.S. White,A.J. Smithson,P.R. Close,M.J. Drinnan,A.J. Prichard,G.J. Gibson. Use of sound recording and oxygen saturation in screening snorers for obstructive sleep apnoea. Clinical Otolaryngology 1994, 19, 218-221.