Newcastle University

Introduction

I am a clinical physiologist who joined the Newcastle team from Australia in 2006. Currently I lead MoveLab, a physical activity and exercise research group in Newcastle.

With a specialist interest in the physiology of chronic disease and how physical activity (or lack of) influences disease, my research interests range from characterising metabolic changes accompanying disease to observing physiological responses to increased physical activity in health and disease.

Qualifications

• PhD - Sydney (Aus)
• MSc - Leeds (UK)
• BSc(hon) - Leeds (UK)

Previous Positions

• Diabetes UK RD Lawrence Fellow;  Newcastle University, Newcastle upon Tyne, UK (Diabetes and physical activity). 
• Research Fellow; Woolcock Institute for Medical Research, Sydney, Australia (Respiratory disorders and metabolic function)
• Research Fellow; Kolling Medical Research Research Institute, Sydney, Australia (Neurogenetics)

Memberships

• Diabetes UK
• European Association for the Study of Diabetes
• Association for the Study of Obesity
• International Society of Behavioral Nutrition and Physical Activity
• British Association of Sport and Exercise Sciences
• Australian Association of Medical Researchers

Honours and Awards

• NIHR Senior Research Fellow, 2011-2016. 
• Innovators in Diabetes (iDia) program recipient, Diabetes UK, 2008
• Diabetes UK RD Lawrence Fellow, June 2007-2010
• Ministry for Science & Medical Research, Postdoctoral Award for Excellence in Science. Australian Society for Medical Research, July 2006.
• Sydney University, Overseas postgraduate scholarship award, 2001-03.

Informal Interests

Mountain biking, windsurfing, snowboarding, rugby, coffee......

Research Interests

My core research projects look at how metabolism can be improved in a number of different metabolic disorders. A significant focus of my research is on how increased physical activity and exercise can be used as a clinical therapy in metabolic disorders (Type 2 diabetes and non-alcoholic fatty liver disease), neuromuscular disease, ageing and in promoting lifelong health and wellbeing.

I also have a strong background in multinuclear magnetic resonance spectroscopy and imaging techniques and use these frequently to investigate metabolism.

In January 2009 I established MoveLab under pump priming funding from the Medical Research Council with clinical colleagues in Newcastle. The objective of this laboratory is to provide a complete translational research platform; building both the evidence base of movement as a clinical therapy and a pathway for delivery into care.

At a basic science level, we have a program of studies investigating the interaction of physical inactivity, physical activity, and exercise upon molecular, genetic and metabolic function with collaborators in the UK and overseas.

At an intermediate level, we are addressing two key questions: what type of activity is best and how much is needed to use physical activity and exercise as a therapy? These studies are identifying the dose response of both resistance and aerobic exercise upon clinical outcomes.

At a clinical delivery level, we are working with clinical care and patient groups to move these findings into clinical care. We are developing the UK’s first accredited professional and patient development pathways for physical activity and exercise for use as a clinical therapy in primary care. This is an exciting area which is expanding rapidly.

Other Expertise

Aside from clinical populations, I also work with healthy people to better understand how people maintain a healthy metabolism (a useful comparison for clinical populations). We are also using exercise as a stimulus to better understand how nutritional interventions can help optimise metabolic control.

Current Work

My current key projects include:

• The implementation of physical activity to management Type 2 diabetes in Primary Care
• The implementation of physical activity to prevent cardiovascular disease in Primary Care  
• Physical activity and exercise in liver disease 
• Physical activity and exercise in Stroke survivors 
• Physical activity and exercise in mitochondrial disease
• Physical activity and exercise in muscular dystrophy
• The development of methods for the assessment of physical activity (OpenMovement)
• The effect of physical activity and exercise on the ageing phenotype
• Islet cell transplantation in Type 1 diabetes
• Sleep apnoea and metabolic control

Postgraduate Supervision

I currently supervise 5 PhD students and 1 masters student.

Esteem Indicators

• NIHR Senior Research Fellow 
• NIHR / MRC College of Experts, Efficacy and Mechanism Evaluation programme.
• Diabetes UK, Young Innovators in Diabetes, program recipient.
• Diabetes UK, RD Lawrence Fellow
• Ministry for Science & Medical Research, Postdoctoral Award for Excellence in Science. Australian Society for Medical Research.

Funding

The laboratory currently receives funding from:

• The National Institute for Health Research (NIHR) 
• The Medical Research Council (MRC)
• Research Councils UK (RCUK) 
• The European Union FP7 Programme
• North East Health Innovation Education Cluster
• NIHR Biomedical Research Centre for Ageing & Age Related Disease 
• Diabetes UK
• County Durham & Darlington NHS Primary Care Trust
• County Durham Sport 
• Newcastle Hospitals Trust Special Trustees
• The Pharmaceutical Industry
• Newcastle University Strategic Fund

Projects

• Fatty Liver: Inhibition of Progression (FLIP)
  Project Leader(s): Prof Christopher P. Day, Prof Ann K. Daly, Prof Mike Trenell, Dr Quentin M. Anstee.
  

  This research is funded by the European Commission Framework 7 Programme.

• Detko E, OHara JP, Thelwall PE, Smith FE, Jakovljevic DG, King RF, Trenell MI. Addition of protein and amino acids to maltodextrin and galactose does not enhance post-exercise liver and muscle glycogen synthesis. British Journal of Nutrition 2013. In Press.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic DG, MacGowan GA, Anstee QM, Day CP, Taylor R, Trenell MI. Cardiac function improves following high intensity intermittent exercise in adults with non-alcoholic fatty liver disease. In: Diabetes UK Annual Professional Conference. 2013, Manchester, UK: Diabetes UK.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic DG, MacGowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. Journal of Hepatology 2013, 58(4), 757-762.
• Denton SJ, Trenell MI, Ploetz T, Savory LA, Bailey DP, Kerr CJ. Cardiorespiratory fitness is associated with hard and light intensity physical activity but not time spent sedentary in 10-14 year old schoolchildren: the HAPPY study. PLoS One 2013, 8(4), e61073.
• Bates MG, Hollingsworth KG, Newman J, Jakovljevic DG, Blamire AM, MacGowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodeling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. European Heart Journal - Cardiovascular Imaging 2013, (epub ahead of print).
• Bates MG, Newman JH, Jakovljevic DG, Hollingsworth KG, Alston CL, Zalewski P, Klawe JJ, Blamire AM, Macgowan GA, Keavney BD, Bourke JP, Schaefer A, McFarland R, Newton JL, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Defining cardiac adaptations and safety of endurance training in patients with m.3243A>g-related mitochondrial disease. International Journal of Cardiology 2013, (epub ahead of print).
• Thelwall PE, Smith FE, Leavitt MC, Canty D, Hu W, Hollingsworth KG, Thoma C, Trenell MI, Taylor R, Rutkowski JV, Blamire AM, Quinn AG. Hepatic Cholesteryl Ester Accumulation in Lysosomal Acid Lipase Deficiency: Non-Invasive Identification and Treatment Monitoring by Magnetic Resonance. Journal of Hepatology 2013. In Press.
• Elson JL, Cadogan M, Apabhai S, Whittaker RG, Phillips A, Trennell MI, Horvath R, Taylor RW, McFarland R, McColl E, Turnbull DM, Gorman GS. Initial development and validation of a mitochondrial disease quality of life scale. Neuromuscular Disorders 2013, 23(4), 324-329.
• Campbell MD, Walker M, Trenell MI, Jakovljevic DG, Stevenson EJ, Bracken RM, Bain SC, West DJ. Large pre- and postexercise rapid-acting insulin reductions preserves glycemia and prevents early- but not late-onset hypoglycemia in patients with type 1 diabetes. Diabetes Care 2013, (epub ahead of print).
• Moore SA, Hallsworth K, Plötz T, Ford GA, Rochester L, Trenell MI. Physical activity, sedentary behaviour and metabolic control following stroke: A cross-sectional and longitudinal study. PLoS One 2013, 8(1), e55263.
• Jakovljevic DG, Hallsworth K, Zalewski P, Thoma C, Klawe J, Day CP, Newton J, Trenell MI. Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease. Clinical Science 2013, 125(3), 143-149.
• Avery L, Flynn D, van Wersch A, Sniehotta FF, Trenell MI. What Behaviour Change Techniques used in Behavioural Interventions are Associated with Improvements in Physical Activity Behaviour and HbA1c in Adults wih Type 2 Diabetes?. In: Diabetes UK Professional Conference 2013. 2013, Manchester: Wiley-Blackwell Publishing Ltd.
• Avery L, Flynn D, van Wersch A, Sniehotta FF, Trenell MI. A systematic review of behaviour change interventions targeting physical activity, exercise and HbA1c in adults with Type 2 diabetes. In: Diabetes UK Annual Professional Conference. 2012, Glasgow, UK: Wiley-Blackwell.
• Hallsworth K, Hollingsworth KG, Thoma C, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
• Hallsworth K, Hollingsworth KG, Thoma C, Taylor R, Day CP, Trenell MI. Cardiac structure and function is altered in adults with non-alcoholic fatty liver disease. In: EuroPRevent: The European Society of Cardiology Congress. 2012, Dublin, Ireland.
• Hollingsworth KG, Gorman GS, Trenell MI, McFarland R, Taylor RW, Turnbull DM, Macgowan GA, Blamire AM, Chinnery PF. Cardiomyopathy is common in patients with the mitochondrial DNA m.3243A>G mutation and correlates with mutation load. Neuromuscular Disorders 2012, 22(7), 592-596.
• Avery L, Flynn D, van-Wersch A, Sniehotta FF, Trenell MI. Changing Physical Activity Behavior in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Behavioral Interventions. Diabetes Care 2012, 35(12), 2681-2689.
• Maddison J, Straub V, Lochmuller H, Turnbull D, Chinnery P, Trennell M, McFarland R, Gorman G, Horvath R, Busbhy K. Clinical research activity in Newcastle MRC centre. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Jakovljevic DG, Moore S, Hallsworth K, Fattakhova G, Thoma C, Trenell MI. Comparison of cardiac output determined by bioimpedance and bioreactance methods at rest and during exercise. Journal of Clinical Monitoring and Computing 2012, 26(2), 63-68.
• Bates MGD, Hollingsworth KG, Newman J, Jakovljevic DG, Keavney BD, Blamire AM, MacGowan GA, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. In: Annual Conference of the British Cardiovascular Society (BCS). 2012, Manchester, UK: BMJ Group.
• Bates M, Hollingsworth K, Taylor R, Turnbull D, Trenell MI, Gorman G. Concentric remodeling and increased myocardial torsion in mitochondrial DNA point mutation carriers. In: 61st Annual Scientific Session and Expo of the American College of Cardiology (ACC). 2012, Chicago, Illinois, USA: Elsevier Inc.
• Avery L, Taylor L, Lievesley M, Mosely K, Speight J, Sniehotta FF, Trenell MI. Development of a behavioural intervention targeting free-living physical activity in adults with type 2 diabetes in primary care: Movement as Medicine. In: Diabetic Medicine: DUK Annual Professional Conference. 2012, Glasgow, UK: Wiley-Blackwell Publishing Ltd.
• Jakovljevic DG, Moore SA, Tan LB, Rochester L, Ford GA, Trenell MI. Discrepancy between cardiac and physical functional reserves in stroke. Stroke 2012, 43, 1422-1425.
• Sivam S, Phillips CL, Trenell MI, Yee BJ, Liu PY, Wong KK, Grunstein RR. Effects of 8 weeks of continuous positive airway pressure on abdominal adiposity in obstructive sleep apnoea. European Respiratory Journal 2012, 40(4), 913-918.
• Bates MG, Hollingsworth KG, Newman J, Jakovljevic D, Dixon BJ, Blamire AM, MacGowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Evidence of early cardiac impairment in m.3243A > G mutation carriers. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Newman J, Jakovljevic D, Bates MG, Turnbull DM, Galna B, Trenell MI, Gorman GS. Improving clinical trials evaluation: physiological and functional correlates in mitochondrial disease. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Hiden H, Woodman S, Watson P, Catt M, Trenell M, Zhang S. Improving the scalability of movement monitoring workflows: An architecture for the integration of the Hadoop File System into e-Science Central. In: Digital Research. 2012, Oxford, UK.
• Jakovljevic DG, Mc Diarmid A, MacGowan GA, Parry G, Schueler S, Trenell MI. Left Ventricular Assist Device Implantation Significantly Improves Everyday Physical Activity and Quality of Life in Patients with Chronic Heart Failure. In: 32nd Anniversary Meeting of the International Society for Heart and Lung Transplantatio. 2012, Prague, Czech Republic: Elsevier Inc.
• Thoma C, Day CP, Trenell MI. Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review. Journal of Hepatology 2012, 56(1), 255-266.
• Jones DEJ, Hollingsworth KG, Jakovljevic DG, Fattakhova G, Pairman J, Blamire AM, Trenell MI. Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: A case control study. European Journal of Clinical Investigation 2012, 42(2), 186-194.
• Moore SA, Hallsworth K, Bluck LJC, Ford GA, Rochester L, Trenell MI. Measuring Energy Expenditure After Stroke Validation of a Portable Device. Stroke 2012, 43(6), 1660-1662.
• Hallsworth K, Thoma C, Moore S, Taylor R, Day CP, Trenell MI. Physical activity levels are lower in people with non-alcoholic fatty liver disease than matched healthy controls. In: Diabetes UK Annual Professional Conference. 2012, Glasgow, UK.
• Jakovljevic DG, Popadic-Gacesa JZ, Barak OF, Nunan D, Donovan G, Trenell MI, Grujic NG, Brodie DA. Relationship between peak cardiac pumping capability and indices of cardio-respiratory fitness in healthy individuals. Clinical Physiology and Functional Imaging 2012, 32(5), 388-393.
• Murphy JL, Newman J, Ratnaike TE, Spendiff S, Falkous G, Blakely EL, Alston CL, Taylor RW, Trenell MI, Gorman GS, Turnbull DM. Resistance training in patients with mitochondrial myopathy. In: United Nations Environment Programme, Mineral Resources Forum. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Prentis JM, Manas DMD, Trenell MI, Hudson M, Jones DJ, Snowden CP. Submaximal cardiopulmonary exercise testing predicts 90-day survival after liver transplantation. In: Liver Transplantation: Meeting of the International Liver Transplantation Society. 2012, Valencia, Spain: John Wiley & Sons, Inc.
• Prentis JM, Trenell MI, Jones DJ, Lees T, Clarke M, Snowden CP. Submaximal exercise testing predicts perioperative hospitalization after aortic aneurysm repair. Journal of Vascular Surgery 2012, 56(6), 1564-1570.
• Moore SA, Jakovljevic DG, Ford GA, Rochester L, Trenell MI. The effect of a community exercise intervention on physiological and physical function following stroke: a randomized, controlled trial. In: UK Stroke Forum 2012 Conference. 2012, Harrogate, UK: Wiley-Blackwell Publishing Ltd.
• Apabhai S, Gorman GS, Sutton L, Elson JL, Ploetz T, Turnbull DM, Trenell MI. Habitual Physical Activity in Mitochondrial Disease. PLoS One 2011, 6(7), e22294.
• Prentis J, Jones DE, Trenell MI, Snowden CP. Impaired cardiorespiratory reserve in primary biliary cirrhosis patients undergoing liver transplant assessment. In: Hepatology: 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). 2011, San Francisco, California, USA: John Wiley & Sons, Inc.
• Horvath R, Reilich R, Krause S, Turnbull DM, Trenell M, Hollingsworth KG, Gorman GS, Czermin B, Holinski-Feder E, Walter MC, Schoser B, Lochmüller H. Neutral lipid storage myopathy due to PNPLA2 mutations may respond to beta-adrenergic treatment. In: UK Neuromuscular Translational Research Conference. 2011, London: Neuromuscular Disorders: Pergamon.
• Yu-Wai-Man P, Trenell MI, Hollingsworth KG, Griffiths PG, Chinnery PF. OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy. Brain 2011, 134(4), e164.
• Newton JL, Pairman J, Hallsworth K, Moore S, Ploetz T, Trenell MI. Physical activity intensity but not sedentary activity is reduced in chronic fatigue syndrome and is associated with autonomic regulation. QJM 2011, 104(8), 681-687.
• Jakovljevic DG, Birks EJ, George RS, Trenell MI, Seferovic PM, Yacoub MH, Brodie DA. Relationship between peak cardiac pumping capability and selected exercise-derived prognostic indicators in patients treated with left ventricular assist devices. European Journal of Heart Failure 2011, 13(9), 992-999.
• Jakovljevic DG, Seferovic PM, Nunan D, Donovan GC, Trenell MI, Grocott-Mason R, Brodie DA. Reproducibility of cardiac power output and other cardiopulmonary exercise indices in patients with chronic heart failure. Clinical Science 2011, 122(4), 175-181.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Day CP, Taylor R, Trenell MI. Resistance exercise improves liver fat and glucose control in people with non-alcoholic fatty liver disease. In: 47th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD). 2011, Lisbon, Portugal: EASD.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, Day CP, Trenell MI. Resistance exercise improves liver fat and glucose control in people with non-alcoholic fatty liver disease. In: Diabetes UK Annual Professional Conference. 2011, London, UK.
• Hallsworth K, Fattakhova G, Hollingsworth K, Thoma C, Moore S, Taylor R, Day CP, Trenell MI. Resistance exercise improves liver lipid, fat oxidation and glucose control in adults with non-alchoholic fatty liver disease independent of weight loss. In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, Day CP, Trenell MI. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut 2011, 60(9), 1278-1283.
• Avery L, Flynn D, van Wersch A, Trenell MI, Sniehotta FF. Systematic Review to identify active ingredients in behaviour change interventions targeting physical activity in adults with type 2 diabetes. In: Psychology & Health: 25th European Health Psychology Conference. 2011, Crete, Greece: Routledge.
• Reilich P, Horvath R, Krause S, Schramm N, Turnbull DM, Trenell M, Hollingsworth KG, Gorman GS, Hans VH, Reimann J, MacMillan A, Turner L, Schollen A, Witte G, Czermin B, Holinski-Feder E, Walter MC, Schoser B, Lochmuller H. The phenotypic spectrum of neutral lipid storage myopathy due to mutations in the PNPLA2 gene. Journal of Neurology 2011, 258(11), 1987-1997.
• Milner KL, van der Poorten D, Trenell MI, Jenkins AB, Xu A, Smythe G, Dore G, Zekry A, Weltman M, Fragomeli V, George J, Chisholm DJ. Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance. Gastroenterology 2010, 138(3), 932-41.
• Jakovljevic DG, Papakonstantinou L, Taylor R, MacGowan G, Trenell MI. Every day physical activity protects against the age related decline in aerobic function but not cardiac pumping capability in normoglycemic women. In: Diabetes and Cardiovascular Disease EASD Study Group. 2010, Belgrade, Serbia.
• Trenell M. Goal-orientated physical activity and diabetes care. Journal of Diabetes Nursing 2010, 14(3), 119.
• Jakovljevic DG, Donovan G, Nunan D, McDonagh S, Trenell MI, Grocott-Mason R, Brodie DA. The effect of aerobic versus resistance exercise training on peak cardiac power output and physical functional capacity in patients with chronic heart failure. International Journal of Cardiology 2010, 145(3), 526-528.
• Phillips CL, Yee BJ, Trenell MI, Magnussen JS, Wang D, Banerjee D, Berend N, Grunstein RR. Changes in regional adiposity and cardio-metabolic function following a weight loss program with sibutramine in obese men with Obstructive Sleep Apnea. Journal of Clinical Sleep Medicine 2009, 5(5), 416-421.
• Stevenson EJ, Thelwall PE, Thomas K, Smith F, Brand-Miller JC, Trenell MI. Dietary glycemic index influences lipid oxidation but not muscle or liver glycogen oxidation during exercise. American Journal of Physiology: Endocrinology and Metabolism 2009, 296(5), E1140-1147.
• Sorensen L, Siddall PJ, Trenell MI, Yue DK. Differences in metabolites in pain processing regions in patients with diabetes and painful neuropathy. Diabetes Care 2008, 31(5), 980-981.
• Trenell MI, Stevenson E, Stockmann K, Brand-Miller J. Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise. British Journal of Nutrition 2008, 99(2), 326-332.
• Trenell MI, Hollingsworth KG, Lim EL, Taylor R. Increased daily walking improves lipid oxidation without changes in mitochondrial function in type 2 diabetes. Diabetes Care 2008, 31(8), 1644-1649.
• van der Poorten D, Milner K-L, Hui J, Hodge A, Trenell MI, Kench JG, London R, Peduto T, Chisholm DJ, George J. Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology 2008, 48(2), 449-457.
• Trenell MI, Ward JA, Yee BY, Phillips C, Kemp GJ, Grunstein RR, Thompson CH. Influence of CPAP therapy on lipid storage, muscle metabolism and insulin action in overweight patients with severe obstructive sleep apnea syndrome. Diabetes, Obesity and Metabolism 2007, 9(5), 679–687.
• Trenell MI, Marshall N, Rogers NL. Sleep and daytime metabolic control: waking to a problem?. Clinical and Experimental Pharmacology and Physiology 2007, 34(1), 1-9.
• Trenell MI, Sue CM, Thompson CH, Kemp GJ. Supplemental oxygen and muscle metabolism in mitochondrial myopathy patients. European Journal of Applied Physiology 2007, 99(5), 541-547.
• Trenell MI, Sue CM, Kemp GJ, Sachinwalla T, Thompson CH. Aerobic exercise and muscle metabolism in patients with mitochondrial myopathy. Muscle & Nerve 2006, 33(4), 524-531.
• Trenell MI, Rooney KB, Sue CM, Thompson CH. Compression garments and recovery from eccentric exercise; 31P-MRS study. Journal of Sport Science and Medicine 2006, 5(1), 106-112.
• Trenell MI, Thompson CH, Sue CM. Exercise and myotonic dystrophy; a 31P-MRS and MRI case study. Annals of Neurology 2006, 59(5), 871-872.
• McKeough Z, Alison J, Bye P, Trenell MI, Sachinwalla T, Thompson CH. Exercise capacity and quadriceps muscle metabolism following training in subjects with COPD. Respiratory Medicine 2006, 100(10), 1817-1825.
• Johnson NA, Stannard S, Mehalski K, Trenell MI, Sachinwalla T, Thompson CH, Thompson M. Intramyocellular triacylglycerol in prolonged cycling with high- and low-carbohydrate availability. Journal of Applied Physiology 2003, 94(4), 1365-1372.
• Bremner K, Bubb WA, Kemp GJ, Trenell MI, Thompson CH. The effect of phosphate loading on erythrocyte 2,3-bisphosphoglycerate levels. Clinica et Chimica Acta 2002, 232(1-2), 111-114.