Professor Paul Corris
Professor of Thoracic Medicine

  • Email: paul.corris@ncl.ac.uk
  • Telephone: +44 (0) 191 213 7462
  • Address: Department of Respiratory Medicine
    Freeman Hospital
    High Heaton
    Newcastle upon Tyne
    NE7 7DN

Research Interests

Basic and clinical science in Lung Transplantation
Main basic group is studying mechanisms leading to airway remodelling following lung transplantation
Main clinical interest is as steering committee member of International Study group organising multicentre clinical studies

Pulmonary vascular disease

Other Expertise

Pulmonary Embolism COPD and Asthma

Current Work

Programme Director of Reseach of Lung group within Immunobiology and Transplantation Research Group
We have ongoing research in
1 MMPs and their role in airway remodelling
2 Role of the innate immune system in the development of OB post lung transplantation
3 gastro oesophageal aspiration and its role in the development of OB post lung transplantation
4 Proinflammatory role of bacterial cell walls and role on epithelial cells of the airway
5 oxidant stress and epithelial cells of the airway
6 EMT and bronchial epithelial cells

Future Research

Pulmonary vascular remodelling

Research Roles

Director of programme of Lung Research in Immunobiology and Transplantation Research Group
Have set up collaborationd with Leiden and Sienna

Postgraduate Supervision

Yes
Supervision of both basic and clinical scientists in proects on pulmonary airway and vascular biology
MD and PhD supervision

Funding

2002-2007 McPhail Charitable Trust £350,000
Bronchial epithelial cell transdifferentiation post lung transplantation

2003-2004 European Respiratory Society £35,000
Epithelial/fibroblast interactions in the genesis of OB post lung transplantation – Visiting Fellowship

2003-2005 Medical Research Council £95,443
Role of Matrix metalloproteinases in the development of OB post lung transplantation

2003-2004 Novartis Pharmaceuticals £60,000
Mechanics leading to obliterative bronchiolitis

2003-2004 Astrazeneca Foundation £20,000
Mechanics leading to obliterative bronchiolitis

2004-2005 European Respiratory Society £35,000
Role of the innate immune system in COPD exacerbations

2005-2006 Glaxo Smith Kline £75,000
The effect of corticosteroids and long acting beta agonists on primary epithelial cell pro-inflammatory activity

2005-2006 Glaxo Smith Kline £75,000
Modification of EMT in bronchial epithelial cells – effects of PDE 4 inhibitor

2005-2006 JRE Scientific Committee £38,000
Studies of Host-Epithelial cell and pathogen interactions in cystic fibrosis patients infected with Burkholderia cepacia

2005-2008 MRC £515,000
The effect of macrolide therapy on sub-clinical infection and inflammation in human lung transplantation