Dr Penny Lovat
Senior Lecturer in Cellular Dermatology and Oncology

  • Email: penny.lovat@ncl.ac.uk
  • Telephone: +44 (0) 191 208 7170
  • Address: Dermatological Sciences
    Institute of Cellular Medicine
    The Medical School,
    Framlington Place,
    Newcastle upon Tyne,
    NE2 4HH

Roles and Responsibilities

Head of Excellence in Learning and Teaching, Institute of Cellular Medicine

Deputy Post Graduate Tutor

Co-organisation of ICM and Regional Dermatology seminar series 

PhD, MD, MRes and BSc student supevisor

PhD and MD internal assessor

BSc Biomedical Sciences personal Tutor

Director, North Eastern Skin Research Fund

Honorary Senior Lecturer Northern Institute for Cancer Research  

Qualifications

1992: MPhil, University of Newcastle upon Tyne and University of Northumbria

1995 PhD, University of Newcastle upon Tyne and University of Northumbria

Previous Positions

2007-2009: Lecturer in Cellular Dermatology and Oncology, Newcastle University

2006-2007: Research Council UK Fellow, Newcastle University

2000-2006: Senior Reserach Assocaite, Newcastle University and University of Rome, 'Tor Vergata'

1995-2000: Research Associate, Newcastle University 

Committee Membership

Committee member of The British Society of Investigative Dermatology (2009-present)

International Melanoma Working Group 

Member of The British Skin Foundation Grants Advisory Board (2011-present)

Institute of Cellular Medicine Postgraduate Committee

Institute of Cellular Medicine Management Board

Institute of Cellular Medicine Executive Board 

Faculty of Medical Sciences Learning and Teaching Committee

Faculty of Medical Sciences Learning and Teaching Regulations Approval Panel 

Faculty of Medical Sciences International Learning and Teaching strategy sub group committee 

Faculty of Medical Sciences Teaching co-ordinators sub-committee

Newcastle University Heads of Teaching and Learning Forum

Society Membership

The British Association for Cancer Research

The European Society for Cancer Research

The British Society for Investigative Dermatology

The European Society for Dermatological Research

The European Cell Deah Organisation

The International Society for Melanoma Research

 

 

 

 

Research Interests

Molecular and immuno-biology of skin cancer and inflammatory skin disease, cellular signalling (apoptosis, autophagy and chemotaxis), biomarker development and stratified medicine for melanoma

Current Research

Targeting apoptosis of melanoma and neuroblastoma in response to ER stress inducing agents as a novel therapeutic strategy.

Deciphering molecular mechanisms mediating dysregulated apoptosis and autophay in metastatic skin cancer.

Defining the contribution of genetic mutations (including B-RAF) in melanoma to deregulated autophagy.

Validation of biomarkers of autophagy in melanoma.

Targeting MEK and VEGF inhibition to prevent melanoma metastasis and angiogenesis

Translational research of novel agents for melanoma therapy in pre clinical and animal models.

Postgraduate supervision

supervisor to PhD, MD and MRes students

Funding:

Cancer Research UK

The British Skin Foundation 

The Psoriasis Association

The Italian Association for Cancer Research

The Wellcome Trust

The Newcastle Healthcare Charity

The Newcastle upon Tyne NHS Foundation Trust 

The JGW Patterson Foundation 

The North Easten Skin Research Fund 

BBSRC case Phd Studentship

MRC/Faculty of Medical Sciences PhD studentship 

Projects

Teaching co-ordinator Institute of Cellular Medicine

Postgraduate teaching

MRes in Medical and Molecular Biosciences:

MMB8008 Cell Signalling in Health and Disease

MEDH099 Reserach project supervsion and assessment

Personal Tutor

Fellow of the Medical Sciences Graduate School 

Undergraduate teaching

BSc (hons) and MSci in Biomedical Sciences, Pharmacology:

CMB3000 Stage 3 Reserach project supevision

B210 Stage 3 Pharmacology project presentation

BMS4099 Stage 4 Reserach project assessment