Research is centered on the design and development of sensor based solutions for biomedical applications and is comprised of two central strands:
A) Development of multi-analyte sensor array platforms for direct, simultaneous intra- and extra-cellular in-vitro monitoring of reactive oxygen species. This work involves the integration of optical and chronoamperometric technologies. The resulting integrated array format enables real-time and continues analysis of ROS initiated events that originate within discrete cellular population.
B) Development of integrated electrochemical and bio-microelectromechanical (bio-MEMS) sensors for application to point-of-care diagnosis of disease processes.
This research is funded by Action for ME and the Newcastle NIHR Biomedical Research Centre in Ageing and Age-Related Disease.