Institute of Cellular Medicine

Staff Profile

Dr Philip Brown

Clinical Training Fellow

Background

Phil completed his medical education at Aberdeen university in 2011 with an intercalated degree in Medical Sciences. After medical school he completed an Academic Foundation post in Middlesbrough and Newcastle before starting an Academic Clinical Fellowship in the North East. He became a member of the Royal College of Physicians in 2015 and started Rheumatology specialist training in 2016. In 2017 he was awarded a Wellcome Clinical PhD Fellowship and has now started his PhD at Newcastle University.

Research

I am interested in biomarkers to predict response to disease modifying therapies (DMARDs) in inflammatory arthritis. I have recently started a PhD project to investigate biomarkers of response for Methotrexate therapy in Rheumatoid Arthritis. I seek to recruit a cohort of early Rheumatoid Arthritis patients and track the accumulation of drug metabolites in their circulating immune cells. I intend to use this and changes in gene expression during early therapy to try to create a predictive tool to determine which patients respond to methotrexate and which do not.

Publications