Newcastle University

Research Interests

The cell biology and genetics of the critically ill patient
Acute lung injury
Chronic respiratory failure

Current Work

Mitochondrial genetics and critical illness
Mitochondrial function in the critically ill

• Ball S, Baudouin SV. The endocrine response to critical illness. In: Hall, GM; Hunter, JM; Cooper, MS, ed. Core Topics in Endocrinology in Anesthesia and Critical Care. Cambridge: Cambridge University Press, 2010, pp.125-133.
• Pyle A, Ibbett IM, Gordon C, Keers SM, Walker M, Chinnery PF, Baudouin SV. A common UCP2 polymorphism predisposes to stress hyperglycaemia in severe sepsis. Journal of Medical Genetics 2009, 46(11), 773-775.
• Pyle A, Burn DJ, Gordon C, Swan C, Chinnery PF, Baudouin SV. Fall in circulating mononuclear cell mitochondrial DNA content in human sepsis. Intensive Care Medicine 2010, 36(6), 956-962.
• Lim WS, Baudouin SV, George RC, Hill AT, Jamieson C, Le Jeune C, Macfarlane JT, Read RC, Roberts HJ, Levy M, Wani M, Woodhead MA. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax 2009, 64(s3), iii1–iii55.
• Baudouin SV. Exogenous surfactant replacement in ARDS - One day, someday, or never?. New England Journal of Medicine 2004. , 351(9), 853-855.
• Richardson A, Turnock C, Patterson L, Baudouin SV. A systematic review of quality improvement programmes in critical care. In: Intensive Care Medicine: 16th Annual Congress of the European Society of Internsive Care Medicine (ESICM). 2003, Amsterdam, Netherlands: Springer.
• Cree RTJ, Chishti A, Gascoigne A, Batchelor A, Shaw I, Warnell I, Bullock R, Hayes N, Karat D, Griffin M, Baudouin SV. Changes in interleukin-8 and vascular endothelial growth factor levels in bronchoalveolar lavage samples following oesophagectomy. In: British Journal of Anaesthesia: Meeting of the Intensive Care Society. 2003, London, UK: Oxford University Press.
• Baudouin SV. Lung injury after thoracotomy. British Journal of Anaesthesia 2003, 91(1), 132-142.
• Baudouin SV, Evans TW. Nutritional support in critical care. Clinics in Chest Medicine 2003, 24(4), 633-644.
• Baudouin S, Evans T. Pulmonary physicians, intensive care medicine and Thorax: an evolving relationship. Thorax 2003, 58(10), 829-832.
• Jaiswal V, Baudouin SV, Ball SG. The relationship of on-admission plasma cortisol to outcome in critical illness: a longitudinal prospective study. In: Endocrine Abstracts: 22nd Joint Meeting of the British Endocrine Societies. 2003, Glasgow, UK: BioScientifica Ltd.
• Burn L, Foster K, Maddison V, Bradford C, Baudouin SV. Is the ACP data set accurate? A network-based survey. British Journal of Anaesthesia 2002, 89(2), 350P-350P.
• Baudouin S, Saunders D, Tiangyou W, Elson J, Poynter J, Pyle A, Keers S, Turnbull D, Howell N, Chinnery P. Mitochondrial DNA and survival after sepsis: A prospective study. Lancet 2005, 366(9503), 2118-2121.
• Clark MF, Baudouin SV. A systematic review of the quality of genetic association studies in human sepsis. Intensive Care Medicine 2006. , 32(11), 1706-1712.
• Robson V, Poynter J, Lawler PG, Baudouin SV. The need for a regional weaning centre, a one-year survey of intensive care weaning delay in the Northern Region of England. Anaesthesia 2003,58 2 161-165.
• Saunders D, Baudouin SV. Clinical trials in sepsis. Clinical Medicine 2005. London, UK:Royal College of Physicians,5 5 431-434.
• Cree RTJ, Warnell I, Staunton M, Shaw I, Bullock R, Griffin SM, Baudouin SV. Alveolar and plasma concentrations of interleukin-8 and vascular endothelial growth factor following oesophagectomy. Anaesthesia 2004,59 9 867-871.
• Baudouin S. Anaesthetist or intensivist: continued debate. Hospital Medicine 2004. ,65 10 630-630.
• Baudouin SV. Chronic obstructive pulmonary disease and asthma in the ITU. Anaesthesia and Intensive Care Medicine 2004. ,5 11 386-388.
• Baudouin SV. Endothelial cell replacement therapy-realistic prospect or pipe dream. Netherlands Journal of Critical Care 2004, 8(5), 363-368.
• Baudouin SV. Invasive mechanical ventilation. Medicine 2004, 32(1), 102-104.
• Chishti AD, Shenton BK, Kirby JA, Baudouin SV. Neutrophil chemotaxis and receptor expression in clinical septic shock. Intensive Care Medicine 2004,30 4 605-611.
• Xiaomei L, Dunn J, Dickinson AM, Gillespie JI, Baudouin SV. Smooth Muscle α-Actin Expression in Endothelial Cells Derived from CD34⁺ Human Cord Blood Cells. Stem Cells and Development 2004,13 5 521-527.
• Baudouin SV. Endothelial cell replacement therapy in the critically ill. In: Vincent, J.-L, ed. Yearbook of Intensive Care and Emergency Medicine. Berlin, Germany: Springer, 2003, pp.21-32.
• Errington D, Baudouin SV. Fluid resuscitation and pre-optimisation before abdominal surgery. In: Taylor, I., Johnson, C, ed. Recent Advances in Surgery. London, UK: Royal Society of Medicine Press, 2003, pp.1-14.
• Bodenham A, MacLennan S, Baudouin SV. Transfusion related lung injury. London:BMJ Books,2002.
• Baudouin SV, Davidson C, Elliott MW, Evans TW, Field D, Kielty S, Pepermann M, Shneerson J, Simmons A, Spencer M, Watts J. National Patients Access Team Critical Care Programme: Weaning and long term ventilation. London: Department of Health, 2002.
• Baudouin SV, Beckett MW, Black C, Collins JV, Davidson C, Evans TW. The Interface between Acute General Medicine and Critical Care. London: Royal College of Physicians, 2002.
• Messer B, Griffiths J, Baudouin SV. The prognostic variables predictive of mortality in patients with an exacerbation of COPD admitted to the ICU: an integrative review. QJM 2012, 105(2), 115-26.
• Voets AM, van den Bosch BJ, Stassen AP, Hendrickx AT, Hellebrekers DM, Van Laer L, Van Eyken E, VanCamp G, Pyle A, Baudouin SV, Chinnery PF, Smeets HJ. Large scale mtDNA sequencing reveals sequence and functional conservation as major determinants of homoplasmic mtDNA variant distribution. Mitochondrion 2011, 11(6), 964-972.
• Jaiswal V, Baudouin SV, Ball SG. A novel gender dimorphism in the response of the gonadal axis to critical illness. In: Endocrine Abstracts: 21st Joint Meeting of the British Endocrine Societies. 2002, Harrogate, UK: BioScientifica Ltd.
• Mutunga M, Fulton B, Bullock R, Batchelor A, Gascoigne A, Gillespie JI, Baudouin SV. Circulating endothelial cells in patients with septic shock. American Journal of Respiratory and Critical Care Medicine 2001, 163(1), 195-200.
• Lu X, Chishti A, Fulton B, Bullock R, Batchelor A, Gascoigne A, Gillespie JI, Baudouin SV. Circulating endothelial progenitor cells in human sepsis. In: British Journal of Anaesthesia. 2001, Oxford University Press.
• Chishti A, Kirby J, Baudouin SV. CXC chemokine receptor expression in severe sepsis in man. Intensive Care Medicine 2001, 27, 7.
• Chishti AD, Dark JH, Kesteven P, Powell H, Snowden C, Shenton BK, Kirby JA, Baudouin SV. Expression of chemokine receptors CXCR1 and CXCR2 during cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery 2001, 122(6), 1162-1166.
• Lamb PJ, Hayes N, Griffin SM, Gascoigne A, Baudouin SV. How can we improve the outcome of oesophagectomy?. British Journal of Anaesthesia 2001, 87(5), 800-800.
• Chishti A, Kirby J, Baudouin SV. Neutrophil CXC chemokine receptor expression in sepsis. In: British Journal of Anaesthesia. 2001, Oxford University Press.
• Robson V, Poynter J, Lawler P, Baudouin SV. North of England regional ventilator dependency study: Does the Northern region need a regional weaning centre. In: Intensive Care Medicine: 14th ESICM Annual Congress. 2001, Geneva, Switzerland: Springer.
• Robson V, Poynter J, Lawler P, Baudouin SV. Northern Regional Ventilator Dependency Study - does the northern region need a Regional Weaning Centre?. In: British Journal of Anaesthesia. 2001, Oxford University Press.
• Baudouin SV. Perioperative risk factors for acute lung injury following elective oesophagectomy. British Journal of Anaesthesia 2001, 87(5), 802-802.