Dr Sophie Cassidy
- Email: firstname.lastname@example.org
- Telephone: 0191 2088264
- Address: 4th Floor William Leech Building
Institute of Cellular Medicine
Newcastle Upon Tyne
I am a clinical exercise physiologist (ACSM) interested in using lifestyle behaviours for the prevention and management of cardio-metabolic diseases.
A large part of my work involves leading clinical research studies. This includes exercise and metabolic testing, the design and implementation of interventions, and evaluation of results. During my PhD I ran a clinical trial which investigated the impact of High Intensity Intermittent Training (HIIT) on cardiac function and metabolism in adults with Type 2 diabetes. Other clinical studies include;
- A home-based physical activity intervention in patients with Heart Failure.
- Resistance and aerobic exercise in patients with non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), and non-alcoholic steatohepatitis (NASH).
- Exercise testing in primary biliary cirrhosis (PBC).
- Pilot study to explore pre-operative exercise and the effects on surgery outcomes.
- The impact of aerobic exercise on sarcopenia.
I am now working on ‘Changing Health’ –an online behaviour change programme and mobile phone app which targets physical activity and diet to induce weight loss in those with pre-diabetes and Type 2 diabetes.
Alongside clinical research, I am also working on the UK Biobank cohort to investigate the role of lifestyle behaviours in cardiometabolic disease from an epidemiological perspective, in collaboration with The University of Sydney.
PhD Lifestyle behaviours and metabolism, Newcastle University
Mres (Distinction) Ageing and Health, Newcastle University
Bsc (Hons-1st class) Sports Science and Physiology, Leeds University
Clinical exercise physiologist (ACSM)
American Diabetes Association
European Association for the Study of Diabetes (EASD)
American College of Sports Medicine (ACSM)
- Houghton D, Thoma C, Hallsworth K, Cassidy S, Hardy T, Burt AD, Tiniakos D, Hollingsworth KG, Taylor R, Day CP, McPherson S, Anstee QM, Trenell MI. Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial. Clinical Gastroenterology and Hepatology 2017, 15(1), 96-102.e3.
- Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI. A cross sectional study of diet, physical activity, television viewing and sleep duration in 233,110 adults from the UK Biobank; the behavioural phenotype of cardiovascular disease and Type 2 diabetes. BMJ Open 2016, 6(3), e010038.
- Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI. A cross-sectional study of physical activity, sedentary behaviour and sleep in 233,110 adults from the UK Biobank: the behavioural phenotype of cardiovascular disease and Type 2 diabetes. In: Diabetes UK Professional Conference. 2016, Glasgow: Wiley-Blackwell Publishing Ltd.
- Mann, LW, Higgins, DM, Peters, CN, Cassidy, S, Hodson, KK, Coombs, A, Taylor, R, Hollingsworth KG. Accelerating MR Imaging Liver Steatosis Measurement Using Combined Compressed Sensing and Parallel Imaging: A Quantitative Evaluation. Radiology 2016, 278(1), 247-256.
- Houghton DH, Thoma CT, Cassidy SC, Hallsworth KH, Hollingsworth KGH, Taylor RT, Day CPD, Anstee QMA, Trenell MIT. Exercise reduces liver fat and improves body composition but not insulin sensitivity or inflammatory markers in non-alcoholic steatohepatitis. In: Diabetes UK Professional Conference. 2016, Glasgow: Wiley-Blackwell Publishing Ltd.
- Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI. High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial. Diabetologia 2016, 59(1), 56-66.
- Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI. In the past 5 years, adults with Type 2 diabetes have made healthy dietary changes but physical activity levels remain lower than healthy adults; a cross-sectional study of 233,110 adults from the UK Biobank cohort. In: Diabetes UK Professional Conference 2016. 2016, Glasgow, UK: Wiley-Blackwell Publishing Ltd.
- Houghton D, Jones TW, Cassidy S, Siervo M, MacGowan GA, Trenell MI, Jakovljevic DG. The effect of age on the relationship between cardiac and vascular function. Mechanisms of Ageing and Development 2016, 153, 1-6.
- Jones T, Houghton D, Cassidy S, MacGowan GA, Trenell MI, Jakovljevic DG. Bioreactance is a reliable method for estimating cardiac output at rest and during exercise. British Journal of Anaesthesia 2015, 115(3), 386-391.
- Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI. Cardiac structure and function are altered in type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control. Cardiovascular Diabetology 2015, 14, 23.
- Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Day CP, Jakovljevic DG, Taylor R, Trenell MI. High intensity intermittent training improves cardiac function and reduces liver fat in adults with Type 2 diabetes: an MRI/S study. In: Diabetes UK Professional Conference. 2015, London, UK: Wiley-Blackwell Publishing Ltd.
- Hallsworth K, Thoma C, Hollingsworth KG, Cassidy S, Anstee QM, Day CP, Trenell MI. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: A randomised controlled trial. Clinical Science 2015, 129(12), 1097-1105.
- Cassidy SA, Hallsworth K, Thoma C, Hollingsworth K, Jakovljevic J, Trenell MI. Cardiac structure and function is altered in adults with metabolic disorders. In: Diabetes UK Professional Conference 2014. 2014, Liverpool, UK: Wiley-Blackwell.
- Cassidy SA, Thoma C, Hallsworth K, Jakovljevic DG, Parikh J, Hollingsworth KG, Taylor R, Trenell MI. High intensity intermittent exercise reverses abnormal cardiac function in people with type 2 diabetes: an MRI/S study. In: 50th General Assembly of the European Association for the Study of Diabetes. 2014, Vienna, Austria: Springer.
- Houghton D, Hallsworth K, Thoma C, Cassidy S, Hardy T, Heaps S, Hollingsworth KG, Taylor R, Day CP, Masson S, McPherson S, Anstee QM, Trenell MI. Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers. Clinical Gastroenterology and Hepatology 2017, 15(10), 1596-1603.e3.
- Cassidy S, Thoma C, Houghton D, Trenell MI. High-intensity interval training: a review of its impact on glucose control and cardiometabolic health. Diabetologia 2017, 60(1), 7-23.
- Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI. Low physical activity, high television viewing and poor sleep duration cluster in overweight and obese adults; a cross-sectional study of 398,984 participants from the UK Biobank. International Journal of Behavioral Nutrition and Physical Activity 2017, 14(1), 57.
- McCoy J, Bates M, Eggett C, Siervo M, Cassidy S, Newman J, Moore SA, Gorman G, Trenell MI, Velicki L, Seferovic PM, Cleland JGF, MacGowan GA, Turnbull DM, Jakovljevic DG. Pathophysiology of exercise intolerance in chronic diseases: the role of diminished cardiac performance in mitochondrial and heart failure patients. Open Heart 2017, 4, e000632.
- Cassidy S, Trenell MI, Anderson KN. The cardio-metabolic impact of taking commonly prescribed analgesic drugs in 133,401 UK Biobank participants. PLoS ONE 2017, 12(12), e0187982.