Newcastle University

Research Interests

Acute Kidney Injury
Critical Care Nephrology
Renal replacement therapy for the critically ill
Chronic haemodialysis

• Sims AJ, Hussein H, Prabhu M, Kanagasundaram NS. Are surrogate assumptions and use of diuretics associated with diagnosis and staging of acute kidney injury after cardiac surgery?. Clinical Journal of the American Society of Nephrology 2012, 7(1), 15-23.
• Smith MP, Marr FE, Kanagasundaram NS. Chloramine reduction by reverse osmosis membranes. Hemodialysis International 2012, 16(1), 120-121.
• Muniraju TM, Lillicrap MH, Horrocks JL, Fisher JM, Clark RMW, Kanagasundaram NS. Diagnosis and management of acute kidney injury: deficiencies in the knowledge base of non-specialist, trainee medical staff. Clinical Medicine 2012, 12(3), 216-221.
• Kanagasundaram NS. Hemodialysis Adequacy and the Hospitalized End-Stage Renal Disease Patient-Raising Awareness. Seminars in Dialysis 2012, 25(5), 516-519.
• Moir JAG, Simms RJ, Wood KM, Talbot D, Kanagasundaram NS. Posttransplant Lymphoproliferative Disorder Presenting as Multiple Cystic Lesions in a Renal Transplant Recipient. American Journal of Transplantation 2012, 12(1), 245-249.
• Griffiths L, Kanagasundaram NS. Assessment and initial management of acute kidney injury. Medicine 2011, 39(7), 390-397.
• Kanagasundaram NS. Defining acute kidney injury: Further steps in the right direction but can detente be maintained?. Critical Care Medicine 2011, 39(12), 2764-2765.
• Kelly RJ, Hill A, Arnold LM, Khursigara G, Kanagasundaram NS, Hillmen P. Eculizumab for patients with paroxysmal nocturnal hemoglobinuria (PNH) is effective during the maintenance of hemodialysis for end stage renal failure. Leukemia Research 2011, 35(4), 560-562.
• Luo Y, Kanagasundaram NS. Microbial Control in Renal Support for Acute Kidney Injury. Seminars in Dialysis 2011, 24(2), 203-207.
• Lewington A, Kanagasundaram S. Renal Association Clinical Practice Guidelines on acute kidney injury. Nephron Clinical Practice 2011, 118(s1), c349-c390.
• Mactier R, Davies S, Dudley C, Harden P, Jones C, Kanagasundaram S, Lewington A, Richardson D, Taal M, Andrews P, Baker R, Breen C, Duncan N, Farrington K, Fluck R, Geddes C, Goldsmith D, Hoenich N, Holt S, Jardine A, Jenkins S, Kumwenda M, Lindley E, MacGregor M, Mikhail A, Sharples E, Shrestha B, Shrivastava R, Steddon S, Warwick G, Wilkie M, Woodrow G, Wright M. Summary of the 5th Edition of the Renal Association Clinical Practice Guidelines (2009-2012). Nephron Clinical Practice 2011, 118(s1), C27-C70.
• Wright RJ, Kanagasundaram NS, Quinton R. Darbepoetin Alfa and Chronic Kidney Disease. New England Journal of Medicine 2010, 362(7), 653-653.
• Thompson A, Zammit-Maempel I, Stafford F, Narayanan M, Kanagasundaram N. Necrotising otitis externa: An unusual cause of cranial nerve palsy in a diabetic haemodialysis patient. Journal of the Royal College of Physicians of Edinburgh 2010, 40(1), 26-28.
• Moore I, Bhat R, Hoenich NA, Kilner AJ, Prabhu M, Orr KE, Kanagasundaram NS. A microbiological survey of bicarbonate-based replacement circuits in continuous veno-venous hemofiltration. Critical Care Medicine 2009, 37(2), 496-500.
• Kanagasundaram NS, Moore I, Hoenich NA. Biofilm in bicarbonate-based replacement fluid circuits in CVVH. Kidney International 2009, 76(6), 682.
• Hussein HK, Lewington AJP, Kanagasundaram NS. General management of acute kidney injury. British Journal of Hospital Medicine 2009, 70(7), M104-M107.
• Kanagasundaram NS. New biomarkers of acute kidney injury: Promise for the future but beware the lure of novelty. Critical Care Medicine 2009, 37(2), 766-767.
• Kanagasundaram N, Hinchliffe W, Murray J. The unwell patient on haemodialysis: What you need to know on an acute medical take. British Journal of Hospital Medicine 2009, 70(10), M152-M155.
• Murray JS, Hinchliffe WT, Kanagasundaram NS. Theory and practical application of blood-based renal replacement therapy. British Journal of Hospital Medicine 2009, 70(12), M189-M191.
• Edey MM, Mead PA, Saunders RE, Strain L, Perkins SJ, Goodship THJ, Kanagasundaram NS. Association of a Factor H Mutation With Hemolytic Uremic Syndrome Following a Diarrheal Illness. American Journal of Kidney Diseases 2008, 51(3), 487-490.
• Kanagasundaram NS, Greene T, Larive AB, Daugirdas JT, Depner TA, Paganini EP. Dosing intermittent haemodialysis in the intensive care unit patient with acute renal failure - Estimation of urea removal and evidence for the regional blood flow model. Nephrology Dialysis Transplantation 2008, 23(7), 2286-2298.
• Simms RJ, Torpey N, Kanagasundaram NS, Baines L, Sayer JA. Emphysematous pyelonephritis leading to end-stage renal failure. NDT Plus 2008, 1(4), 264-265.
• Wright SE, Baudouin SV, Kaudeer N, Shrestha S, Malone J, Burn L, Kanagasundaram NS. Patient flow from critical care to renal services: a year-long survey in a critical care network. QJM: An International Journal of Medicine 2008, 101(8), 643-648.
• Kanagasundaram NS. Prescription of an intermittent haemodialysis dose using urea kinetic modelling is feasible in the critically ill patient. Nephrology Dialysis Transplantation 2008, 23(3), 1075-1075.
• Kanagasundaram NS, Jones KE. Transfer of patients with acute kidney injury to specialist renal services - physiological early-warning systems, applied prior to transfer from outside hospitals, can identify those at risk of deterioration. QJM: An International Journal of Medicine 2008, 101(3), 249-250.
• Davies J, Healey DA, Wood KM, Jones K, Kanagasundaram NS. Acute renal failure due to mantle cell lymphoma - a case report and discussion of the literature. Clinical Nephrology 2007, 67(6), 394-396.
• Refaie R, Moochhala SH, Kanagasundaram NS. How we estimate GFR - A pitfall of using a serum creatinine-based formula. Clinical Nephrology 2007, 68(4), 235-237.
• Sewpaul A, Sayer JA, Mohamed MAS, Ahmed A, Shaw M, Prabhu VR, Wood K, Jones NA, Talbot D, Kanagasundaram NS. Rapid onset intratubular calcification following renal transplantation requiring urgent parathyroidectomy. Clinical Nephrology 2007, 68(1), 47-51.
• Kanagasundaram NS. Renal replacement therapy in acute kidney injury: an overview. British Journal of Hospital Medicine 2007, 68(6), 292-297.
• Kanagasundaram NS, Paganini EP. Acute renal failure on the intensive care unit. Clinical Medicine 2005, 5(5), 435-440.
• Kanagasundaram NS, Posch A, Larive AB, Paganini EP, Van Lente F. Direct dialysis quantification: Investigation of the impact of dialysate preservation techniques on solute assays. Blood Purification 2004, 22(5), 435-439.
• Ikizler TA, Sezer MT, Flakoll PJ, Hariachar S, Kanagasundaram NS, Gritter N, Knights S, Shyr Y, Paganini E, Hakim RM, Himmelfarb J. Urea space and total body water measurements by stable isotopes in patients with acute renal failure. Kidney International 2004, 65(2), 725-732.
• Kanagasundaram NS, Larive AB, Paganini EP. A preliminary survey of bacterial contamination of the dialysate circuit in continuous veno-venous hemodialysis. Clinical Nephrology 2003, 59(1), 47-55.
• Kanagasundaram NS, Larive AB, Paganini EP. Continuous renal replacement therapies: potential for fluid-side bacterial contamination?. Critical Care Medicine 2003, 31(6), 1889-1890.
• Kanagasundaram NS, Greene T, Larive AB, Daugirdas JT, Depner TA, Garcia M, Paganini EP, PICARD Study Group. Prescribing an equilibrated intermittent hemodialysis dose in intensive care unit acute renal failure. Kidney International 2003, 64(6), 2298-2310.
• Liangos O, Sakiewicz PG, Kanagasundaram NS, Hammel J, Pajouh M, Seifert T, Paganini EP. Dialyzer fiber bundle volume and kinetics of solute removal in continuous venovenous hemodialysis. American Journal of Kidney Diseases 2002, 39(5), 1047-1053.
• Paganini EP, Kanagasundaram NS, Larive B, Greene T. Prescription of adequate renal replacement in critically ill patients. Blood Purification 2001, 19(2), 238-244.
• Paganini EP, Larive B, Kanagasundaram NS. Severity scores and outcomes with acute renal failure in the ICU setting. Contributions to Nephrology 2001, 132, 181-195.
• Kanagasundaram NS, Larive AB, Paganini EP. A fractional dialysate collection method to estimate solute removal in continuous venovenous hemodialysis. Kidney International 2000, 58(6), 2579-2584.
• Kanagasundaram NS, Sakiewicz PG, Liangos O, Paganini EP. Biocompatibility and acute renal failure. The Lancet 2000, 355(9200), 313-313.
• Kanagasundaram NS, Perry EP, Turney JH. Aneurysm of the splenic artery in a patient with autosomal dominant polycystic kidney disease. Nephrology Dialysis Transplantation 1999, 14(1), 183-184.
• Kanagasundaram NS, Paganini EP. Critical care dialysis - a Gordian knot (but is untying the right approach?). Nephrology Dialysis Transplantation 1999, 14(11), 2590-2594.
• Fletcher S, Kanagasundaram NS, Rayner HC, Irving HC, Fowler RC, Brownjohn AM, Turney JH, Will EJ, Davison AM. Assessment of ultrasound guided percutaneous ethanol injection and parathyroidectomy in patients with tertiary hyperparathyroidism. Nephrology Dialysis Transplantation 1998, 13(12), 3111-3117.
• Kanagasundaram NS, Macdougall IC, Turney JH. Massive haemoperitoneum due to rupture of splenic infarct during CAPD. Nephrology Dialysis Transplantation 1998, 13(9), 2380-2381.
• Kanagasundaram NS, Allan BJ, Kessel D, Newstead CG, Worth DP. Nephrotic syndrome after successful renal angioplasty. Nephrology Dialysis Transplantation 1998, 13(3), 767-768.
• Kumar A, Kanagasundaram NS, Collyns TA, Davison AM. Plasma exchange and haemodiafiltration in fulminant meningococcal sepsis. Nephrology Dialysis Transplantation 1998, 13(2), 484-487.
• Kanagasundaram NS, Bandyopadhyay D, Brownjohn AM, Meaney JF. The diagnosis of renal vein thrombosis by magnetic resonance angiography. Nephrology Dialysis Transplantation 1998, 13(1), 200-202.
• Kanagasundaram NS, Fletcher S, Gupta S, Davison AM. Acute small-bowel obstruction following mesenteric perforation by CAPD catheter. Nephrology Dialysis Transplantation 1997, 12(3), 599-600.
• Jones CH, Kanagasundaram NS, Coral AP, Coyne JD, Will EJ. Combined Waldenström's macroglobulinaemia associated AL and beta-2-microglobulin amyloidosis. Nephrology Dialysis Transplantation 1997, 12(12), 2708-2712.