Dr Xiao Wang
Lecturer
Email: x.n.wang@ncl.ac.uk Telephone: +44 (0) 191 282 0641 Fax: +44 (0) 191 222 6794 Address: Institute of Cellular Medicine
Haematological Sciences
Leech Building, Medical School
University of Newcastle upon Tyne
NE2 4HH
Haniffa M, Shin A, Bigley V, Teo P, See P, Wasan P, McGovern N, Wang XN, Malinarich F, Malleret B, Poidinger M, Gehring A, Bertoletti A, Collin M, Ginhoux F. Identification of the human cross-presenting migratory dendritic cell .
In: Meeting of the British Society for Investigative Dermatology . 2012, Exeter, UK: Wiley-Blackwell Publishing Ltd.
Stocki P, Wang XN, Dickinson AM. Inducible Heat Shock Protein 70 Reduces T cell Responses and Stimulatory Capacity of Monocyte-derived Dendritic Cells .
Journal of Biological Chemistry 2012, 287 (15), 12387-12394.
Haniffa M, Shin A, Bigley V, McGovern N, Wang XN, Teo P, Sng D, Won JM, Marinarich FG, Malleret B, See P, Larbi A, Zhou H, Poidinger M, Pagan S, Cookson S, Dickinson R, Connolly J, Gehring A, Bertoletti A, Collin M, Ginhoux F. CD141(+) human migratory dendritic cells are homologous to murine CD103+dendritic cells and excel at exogenous antigen cross-presentation .
In: Immunology: Annual Congress of the British Society for Immunology . 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
Atarod S, Norden J, Kuzyk-Czucha A, Bogunia-Kubik K, Turner B, Ambler L, Wang XN, Collin M, Dickinson AM. Correlation of HSPA1Lexpression with the development of graft-versus-host disease .
In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation . 2011, Paris, France: Nature Publishing Group.
Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Spence L, Pagan S, Carey C, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Jackson G, Dick JE, Hambleton S, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency: a novel but potentially fatal haematological disorder curable with haematopoietic stem cell transplantation .
In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation . 2011, Paris, France: Nature Publishing Group.
Dickinson RE, Griffin H, Bigley V, Reynard LN, Hussain R, Haniffa M, Lakey JH, Rahman T, Wang XN, McGovern N, Pagan S, Cookson S, McDonald D, Chua I, Wallis J, Cant A, Wright M, Keavney B, Chinnery PF, Loughlin J, Hambleton S, Santibanez-Koref M, Collin M. Exome sequencing identifies GATA-2 mutation as the cause of the dendritic cell, monocyte, B and NK lymphoid deficiency .
Blood 2011, 118 (10), 2656-2658.
Novota P, Zinocker S, Norden J, Wang XN, Sviland L, Opitz L, Salinas-Riester G, Rolstad B, Dickinson AM, Walter L, Dressel R. Expression profiling of major histocompatibility and natural killer complex genes reveals new candidates for controlling risk of graft versus host disease .
In: Tissue Antigens: 25th Conference on European Immunogenetics and Histocompatibility . 2011, Prague, Czech Republic: Wiley-Blackwell Publishing, Inc.
Stocki P, Wang XN, Morris NJ, Dickinson AM. HSP70 Natively and Specifically Associates with an N-terminal Dermcidin-derived Peptide That Contains an HLA-A*03 Antigenic Epitope .
Journal of Biological Chemistry 2011, 286 (14), 12803-12811.
McGovern N, Bigley V, Allen C, Haniffa M, Wang XN, Dickinson R, Pagan S, Windebank K, McClain K, Ginhoux F, Merad M, Collin M. Human Langerin plus dendritic cells are independent of epithelial Langerhans cells; a novel perspective on Langerhans cell histiocytosis .
In: Immunology: Annual Congress of the British Society for Immunology . 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
Sturgess K, Slatter M, Bigley V, Haniffa M, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Chua I, Wallis J, Lordan J, Morgan C, Cant A, Gennery A, Edmondson R, Bacon C, Black F, Kirkham N, Jackson GH, Hambleton S, Collin MP. Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation .
In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH) . 2011, San Diego, California, USA: American Society of Hematology.
Mavin ER, Dickinson AM, Wang XN. Regulatory T cell suppressive functions are not affected by cryo-preservation .
In: Immunology: Annual Congress of the British Society for Immunology . 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern N, Jardine L, Pagan S, Dimmick I, Chua I, Wallis J, Lordan J, Morgan C, Kumararatne DS, Doffinger R, van der Burg M, van Dongen J, Cant A, Dick JE, Hambleton S, Collin M. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency .
Journal of Experimental Medicine 2011, 208 (2), 227-234.
Ruffin N, Ahmed SS, Osorio LM, Wang XN, Jackson GH, Collin MP, Ekre HP, Chiodi F, Dickinson AM. The Involvement of Epithelial Fas in a Human Model of Graft Versus Host Disease .
Transplantation 2011, 91 (9), 946-951.
Kuzyk A, Bogunta-Kubik K, Jackson G, Cullin M, Wang XN, Dickinson A. HSP70-hom gene polymorphism as a risk factor of graft-versus-host disease .
In: 2nd European Congress of Immunology (ECI) . 2009, Berlin, Germany: Medimond SRL.
Collin M, Munster D, Clark G, Wang XN, Dickinson A, Hart D. Antibody-mediated suppression of allogeneic responses by targeting the tissue dendritic cell: A potential role for CMRF-44 where alemtuzumab fails .
In: Blood: 45th Annual Meeting of the American Society of Hematology . 2003, San Diego, California, USA: American Society of Hematology.
Dickinson AM, Stark G, Cullup H, Jarvis M, Wang XN, Middleton PG. Cytokine Gene Polymorphism in Transplantation .
Hematopoietic Stem Cells Research and Clinical Applications 2003, European School of Haematology .
Jarvis M, Marzolini MAV, Wang XN, Sviland L, Dickinson AM. Heat shock protein 70: Correlation of expression with degree of graft-versus-host response and clinical GVHD: Quantitative assessment using laser scanning confocal microscopy .
In: Genes and Immunity: 17th European Histocompatability Conference . 2003, Baden, Germany: Nature Publishing Group.
Cullup H, Wang XN, Dickinson AM. HLA-matcing influences the production of the IL-1 family of cytokines in an alloimmune response .
In: Genes and Immunity: 17th European Histocompatability Conference . 2003, Baden, Germany: Nature Publishing Group.
Dickinson AM, Wang XN, Sviland L, Cullup H. Neutralisation of IL-1 receptor antagonist is associated with increased graft versus host damage demonstrated in a human in vitro modified model of graft versus host disease .
In: Blood: 45th Annual Meeting of the American Society of Hematology . 2003, San Diego, California, USA: American Society of Hematology.
Cullup H, Wang XN, Dickinson AM. The level of IL-1B and IL-1RA in MLR supernatants is associated with the incidence of aGVHD following HLA-matched sibling BMT .
In: Genes and Immunity: 17th European Histocompatability Conference . 2003, Baden, Germany: Nature Publishing Group.
Dickinson A, Wang XN. Are the functional assays useful in predicting graft-versus-host disease in HLA-matched sibling bone marrow transplantation? .
Transplantation 2001, 72 (6), 1168-1168.
Sviland L, Hromadnikova I, Sedlacek P, Cermakova M, Stechova K, Holler E, Eissner G, Schulz U, Kolb HJ, Jackson G, Wang XN, Dickinson AM. Histological correlation between different centers using the skin explant model to predict graft-versus-host disease following bone marrow transplantation .
Human Immunology 2001, 62 (11), 1277-1281.
Wang XN, Dickinson AM, Sviland L, Vyth-Dreese FA, Jackson GH, Schumacher TNM, Haanen JBAG, Mutis T, Goulmy E. Minor histocompatibility antigen specific CTLs and in situ skin graft versus host reactions .
In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH) . 2001, Orlando, Florida, USA: American Society of Hematology.
Cohen SBA, Wang XN, Dickinson A. Can cord blood cells support the cytokine storm in GvHD? .
Cytokine and Growth Factor Reviews 2000, 11 (3), 185-197.