POSAT


Prolong Organ Survival After Transplantation (POSAT) March 2014-September 2017

Newcastle University has vacancies for 4 early stage PhD training fellows to foster translational research into the Preservation of Organ Survival After Transplantation (POSAT). The POSAT scheme will address this by training early stage researchers to function at this dynamic interface in order to address specific problems which contribute to chronic graft failure. This programme will meet two specific objectives: development of methods to reduce organ inflammation immediately after transplantation (thereby preserving long-term graft function), and identification of biomarkers which allow transplant patients to be stratified allowing individualized drug treatment. These complementary objectives will be addressed by allocation of a trainee-specific project to each of the 4 early stage researchers. Although based at Newcastle University, each trainee will spend significant periods working with carefully selected private sector partners and academics at another university in the NorthEast of England.

Project 1: Analysis and manipulation of the time zero allograft transcriptome.

Project 2: Analysis and Amelioration of Ischemia-Reperfusion Injury

Project 3: Identification of molecular biomarkers of fibrosis

Project 4: Analysis of tissue re-modelling associated with allograft rejection

Two appointees will commence work in March, 2014 and a further two in October, 2014. Marie Curie funding is intended to promote the mobility of early stage researchers (no more than four years research experience after the end of a first degree) within the EU. For this reason, candidates with EU citizenship are eligible to apply for these posts if they have not been resident within the UK for more than 12 months within the 3 years prior to the project start dates. Successful candidates will hold excellent first and masters level degrees in a relevant subject and will be fluent in English (minimum IELTS level 6).

Coordinator: Professor Simi Ali

For further information please contact: Professor Simi Ali Simi.Ali@newcastle.ac.uk or Professor John A Kirby J.A.Kirby@newcastle.ac.uk

Sponsored by the EUROPEAN COMMISSION FP7, Marie Curie-Initial Training Networks (ITN), Innovative Doctoral Programmes (IDP)