Institute of Cellular Medicine

Metabolic Medicine & Fibrosis

Metabolic Medicine and Fibrosis

Overview

This theme unites both basic and clinical scientists across a breadth of translational research areas. These include nutrition, exercise, metabolism, hepatology and fibrosis.

We have a goal to discern

  • genetic/epigenetic
  • molecular
  • cellular 

mechanisms driving metabolic diseases and organ fibrosis

Metabolic disorders/dysfunction or persistent tissue injury and inflammation that drive fibrosis can affect many organs. These include the heart, pancreas, muscle, liver, lung, kidney, knee and skin. 

Lifestyle factors such as physical activity and diet can also affect these diseases.

Through our research, we aim to advance our understanding of progression of these diseases.

This enables us to develop new therapeutic strategies for treatment of metabolic and fibrotic diseases. It also helps us improve patient wellbeing and and their ability to live healthier lives.

Research interest

Research in this theme focuses on:

  • understanding fundamental processes of metabolism, tissue injury, inflammation, fibrosis and tissue regeneration
  • clinical phenotyping and interrogation of patient disease samples to: 
    • aid biomarker discovery
    • develop non-invasive imaging approaches
    • identify new targets for therapy
  • understanding how nutrition and exercise can modulate disease and lead to healthy ageing

Research groups/centres within the theme include: 

Our researchers look at the factors that drive fibrosis, which is the scarring of various organs.
Our researchers look at the factors that drive fibrosis, which is the scarring of various organs.

Academics

Academics working within this research theme include:

Honorary Staff

Our honorary staff for this research theme are listed below.

Dr Terry Aspray
Honorary Clinical Senior Lecturer

Email:
Telephone: +44 (0) 191 213 7975

Dr Alison Brown
Honorary Clinical Senior Lecturer

Dr Mark Hudson
Honorary Clinical Senior Lecturer

Dr Suren Kanagasundaram
Honorary Clinical Senior Lecturer

Research Staff

Here you will find details of our staff for this research theme.

Dr Ahmad Al-Mrabeh
Research Associate

Email:
Telephone: +44 (0) 191 208 1160

Dr Leah Avery
Senior Research Associate & Health Psychologist

Email:
Telephone: +44 (0)191 208 7132

Dr Stephen Ball
Training Fellow

Email:
Telephone: +44 (0) 191 208 3886

Dr Hyang-Min Byun
Newcastle University Research Fellow

Email:

Dr Sophie Cassidy
Research Associate

Email:
Telephone: 0191 2088264

Dr Paul Catterson
Senior Clinical Fellow

Dr Shruti Chachra
Research Assistant

Dr Brian Ford
Research Associate

Email:
Telephone: +44 (0) 191 208 8798

Dr Olivier Govaere
Research Associate

Email:

Dr Timothy Hardy
Associate Clinical Researcher

Dr Djordje Jakovljevic
Senior Lecturer (Research) in Cardiovascular Ageing and Heart Failure

Email:
Telephone: +44 (0) 191 208 8257

Dr Sabine Klein
Research Associate

Dr Daniel West
Newcastle University Research Fellow

Email:
Telephone: 0191 2087076

Dr Naomi Willis
Associate Researcher

Dr Caroline Wilson
Newcastle University Research Fellow

Dr Julie Worrell
Research Associate

Dr Sviatlana Zhyzhneuskaya
Clinical Research Associate