Functional Genetics
Technical Manager: Paul Cairns
This is a Comparative Biology Centre facility located in the Institute of Genetic Medicine. The modelling of genetic defects in in vivo systems is an essential
step towards understanding developmental processes and the pathogenesis of human
disease. Led by Drs Heiko Peters and Colin Miles the facility generates transgenic
and gene knockout mice to provide researchers at the Institute with model systems
for gene function analyses. Based on Leica DMIRE2 and DMIRB microscopes, two
state-of-the-art microinjection units are available for pronucleus and blastocyst
injections. Dedicated ES cell and organ culture facilities, and high quality
stereomicroscopes for phenotype analysis are affiliated to this unit.
