Publication:

PGD and heteroplasmic mitochondrial DNA point mutations: a systematic review estimating the chance of healthy offspring (2012)

Author(s): Hellebrekers DMEI, Wolfe R, Hendrickx ATM, de Coo IFM, de Die CE, Geraedts JPM, Chinnery PF, Smeets HJM

      • Date: 28-03-2012
      • Journal: Human Reproduction Update
      • Volume: 18
      • Issue: 4
      • Pages: 341-349
      • Publication type: Review
      • Bibliographic status: Published

      Keywords: PGD mitochondrial DNA mutations heteroplasmy PREIMPLANTATION GENETIC DIAGNOSIS HUMAN EMBRYOFETAL DEVELOPMENT RED FIBERS MERRF MTDNA MUTATION PRENATAL-DIAGNOSIS 1555A-GREATER-THAN-G MUTATION SKELETAL-MUSCLE MELAS PREVALENCE SEGREGATION

      Staff

      Professor Patrick Chinnery
      Institute Director