Causes and Patterns of Disease

Key Publications

  • Khoshnood B, Loane M, Garne E, Addor MC, Arriola L, Bakker M, Barisic I, Blanca S, Boyd P, Calzolari E, Doray B, Draper E, Gatt M, Haeusler M, Melve KK, Latos-Bielenska A, McDonnell B, Mullaney C, Nelen V, O'Mahony M, Pierini A, Queisser-Luft ARandrianaivo H, Rankin J, Rissmann A, Salvador J, Tucker D, Verellen-Dumoulin C, Wellesley D, Zymak-Zakutnya N, Dolk H. Recent Decrease in the Prevalence of Congenital Heart Defects in Europe. The Journal of Pediatrics 2013, 162(1): 108-113.e2.
  • Boyle B, McConkey R, Garne E, Loane M, Addor MC, Bakker MK, Boyd PA, Gatt M, Greenlees R, Haeusler M, Klungsoyr K, Latos-Bielenska A, Lelong N, McDonnell R, Metneki J, Mullaney C, Nelen V, O'Mahony M, Pierini A, Rankin J, Rissman A, Tucker D, Wellesley D, Dolk H. Trends in the prevalence, risk and pregnancy outcome of multiple births with congenital anomaly:a registry based study in 14 European countries 1984-2007. BJOG: An International Journal of Obstetrics & Gynaecology 2013. In Press.
  • Loane M, Morris JK, Addor MC, Arriola L, Budd J, Doray B, Garne E, Gatt M, Haeusler M, Khoshnood B, KlungsoyrMelve K, Latos-Bielenska A, McDonnell B, Mullaney C, O'Mahony M, QueiBer-Wahrendorf A, Rankin J, Rissmann A, Rounding C, Salvador J, Tucker D, Wellesley D, Yevtushok L, Dolk H. Twenty-year trends in the prevalence of Down sydrome and other trisomies in Europe: impact of maternal age and prenatal screening. European Journal of Human Genetics 2013, 21(1): 27-33.
  • Glinianaia SV, Embleton ND, Rankin J. A systematic review of studies of quality of life in children and adults with selected congenital anomalies. Birth Defects Research Part A: Clinical and Molecular Teratology 2012, 94(7): 511-520.
  • Best K, Tennant PWG, Bell R, Rankin J. Impact of maternal body mass index on the antenatal detection of congenital anomalies. BJOG 2012;119:1503-11.
  • Hannon T, Tennant PWG, Rankin J, Robson SC. Epidemiology, natural history, progression and postnatal outcome of severe fetal ventriculomegaly. Obstetrics and Gynecology 2012, 120(6): 1345-1353.
  • Heslehurst N, Sattar N, Rajasingam D, Wilkinson J, Summerbell C, Rankin J. Existing maternal obesity guidelines may increase inequalities between ethnic groups: a national epidemiological study of 502,474 births in England. BMC Pregnancy & Childbirth 2012, 12(1): 156.
  • Graham R, Embleton N, Farnworth A, MAson K, Rankin J, Robson S. Experiences of Reproductive Loss: The Importance of Discretion in Caring for a Patient Group with Diverse Views. In: Earle, S., Komaromy, C., Layne, L, ed. Understanding Reproductive Loss: Perspectives on Life, Death and Fertility. Surrey: Ashgate, 2012, pp.205-219.
  • Bell R, Tennant PWG, Rankin J. Fetal and infant outcomes in obese pregnant women. In: Gillman, M.W., Poston, L, ed. Maternal Obesity. Cambridge, UK: Cambridge Press, 2012, pp.56-69. Bell R, Glinianaia S, Tennant PWG, Bilous R, Rankin J. Peri-conception hyperglycaemia and nepthropathy are associated with risk of congenital anomaly in women with pre-existing diabetes: a population-based cohort study. Diabetologia 2012; 55(4): 936-947.
  • Best KM, Tennant PWG, EUROCAT Working Group, Rankin J. Prevalence of small intestinal atresia in Europe, 1990-2006. Archives of Disease in Childhood Fetal & Neonatal Edition 2012:F1-F6.
  • Cole TS, Johnstone IC, Pearce MS, Fulton B, Cant AJ, Gennery AR, Slatter MA.  Outcome of children requiring intensive care following haematopoietic stem cell transplant for primary immunodeficiency and other non-malignant disorders. Bone Marrow Transplantation 2012;47:40–45
  • Cole TS, Jones LKR, McGrogan P, Pearce MS, Flood TJ, Cant AJ, Goldblatt D, Thrasher AJ, Gennery AR, McKendrick F, Titman P. Emotional and behavioural difficulties in chronic granulomatous disease. Archives of Disease in Childhood 2012; 97: 87.
  • Garne E, Loane M, Dolk H, Barisic I, Addor M-C, Arriola L, Bakker M, Calzolari E, Dias CM, Doray B, Gatt M, Melve KK, Nelen V, O'Mahony M, Pierini A, Randrianaivo-Ranjatoelina H, Rankin J, Rissmann A, Tucker D, Verellun-Dumoulin C, Wiesel A. Spectrum of congenital anomalies in pregnancies with pregestational diabetes. Birth Defects Research Part A 2012; 94(3):134-140.
  • Groom A, Potter C, Swan DC, Fatemifar G, Evans DM, Ring SM, Turcot V, Pearce MS, Embleton ND, Davey Smith G, Mathers JC, Relton CL. Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass. Diabetes 2012; 61: 391-400.
  • Hayes L, Hawthorne GC, Unwin NC. Undiagnosed diabetes in the over-60s: performance of the APHO diabetes prevalence model in a general practice.  Diabetic Medicine 2012; 29(1): 115-120.
  • Kengne AP, Sobngwi E, Chalmers J. Multiple risk factor interventions and inflammatory biomarkers in high risk individuals with type 2 diabetes. Diabetes Research and Clinical Practice 2012; 95(3): 386-388.
  • Kim KP, Berrington de González A, Salotti JA, McHugh KM, Craft AW, Parker L, Pearce MS, Lee C. Development of a database of organ doses for pediatric and young adult CT scans in the United Kingdom. Radiation Protection Dosimetry 2012
  • Lee T, Rutter M, Blanks R, Moss S, Goddard A, Chilton A, Nickerson C, McNally RH, Patrick J, Rees C. Colonoscopy of quality measures experience from the NHS bowel cancer screening programme,Gut 2012; 61(7):1050-1057.
  • McNally RJ, James PW, Picton SV, McKinney PA, van Laer M, Feltbower RG. Space-time clustering of childhood central nervous system tumours in Yorkshire, UK. BMC Cancer 2012; 12(1):13.
  • Proctor SJ, Wilkinson J, Jones G, Watson GC, Lucraft HH, Mainou-Fowler T, Culligan D, Galloway MJ, Wood KM, McNally RJ, James PW, Goodlad JR. Prospective evaluatin of treatment outcome in 175 patients with Hodgkin Lymphone (HL) aged 60 years or over: The SHIELD study. Blood 2012; 119(250): 6005-6015.
  • Pearce MS, Tennant PWG, Mann KD, Pollard TM, McLean L, Kaye B, Parker L. Lifecourse predictors of mammographic density: The Newcastle Thousand Families cohort Study. Breast Cancer Research and Treatment 2012; 131(1):187-195.
  • Pearce MS, Ahmed A, Tennant PWG, Parker L, Unwin NC. Lifecourse predictors of adult fibrinogen levels: The Newcastle Thousand Families Study. International Journal of Cardiology 2012;155(2):206-211.
  • Pearce MS, Salotti JA, McHugh K, Kim KP, Craft AW, Ron E, Parker L. Socio-economic variation in the use of CT scans in young people in the North of England, 1990-2002. BMC Health Services Research 2012; 12: 24.
  • Pearce MS, Glinianaia SV, Ghosh R, Rankin J, Rushton S, Charlton M, Parker L, Pless-Mulloli T. Particulate matter exposure during pregnancy is associated with  birth weight, but not gestational age, 1962-1992. Environmental Health 2012; 11(1):13.
    Pearce MS, McConnell JC, Barrett LM, Mathers JC, Parker L, Relton CL. Global LINE-1 DNA methylation is associated with blood glycaemic and liquid profiles.  International Journal of Epidemiology 2012; 41: 210-217.
    Pedersen RN, Calzolari E, Husby S, Garne E, EUROCAT Working Group. Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions. Archives of Disease in Childhood Fetal & Neonatal Edition 2012;97: 227-232.
  • Prathapan S, Adams J, Bythell M, Rankin J. Are there differences in uptake of Down syndrome screening by deprivation? Prenatal Diagnosis 2012; 32(3):293-295.
  • Relton CL. Groom A, St Pourcain B, Sayers AE, Swan DC, Embleton ND, Pearce MS, Ring SM, Northstone K, Tobias JH, Trakalo J, Ness AR, Shaheen SO, Davey Smith G. DNA methylation patterns in cord blood DNA predict body composition in childhood. PLoS ONE 2012; 7: e31821.
  • Wright CM, Cox KM, Sherriff A, Franco-Villoria M, McColl J, Pearce MS, Parkinson K, Adamson AJ. To what extent do infancy weight gain and eating avidity predict later adiposity? Public Health Nutrition 2012;15(4):656-662.
  • Yarnall A, Hayes L, Hawthorne G, Candlish C, Aspray T. Diabetes in care homes: current care standards and residents’ experience. Diabetic Medicine 2012; 29(1):132-35.