|Semester 1 Credit Value:||20|
To introduce the principles of NMR spectroscopy and to familiarise students with the analysis of the NMR spectra of some organic and inorganic compounds; to explain the principles of X-ray diffraction by single crystals and the application of these principles in practical structure determination; to provide students with an appreciation and understanding of all aspects of modern mass spectrometry, building on their knowledge of traditional electron impact mass spectrometry; to provide the necessary background for the interpretation of the vibrational spectra of inorganic and organic molecules
Magnetic Resonance Spectroscopy and Organic Compound Identification
Dr C Wills
1 Revision of NMR spectroscopy
2 Chemical shifts and splitting patterns
3 Carbon 13 NMR and 2D NMR and their uses
4-6 Interpreting NMR spectra and other analytical data in identification of organic compounds
Magnetic Resonance Spectroscopy and Inorganic Compound Identification
Dr C Wills
1 More complex NMR techniques and their uses
2-3 Nuclei with spins >1/2 and their spectra
4 Dynamic NMR and interpreting temperature dependent spectra
5-6 Identification of inorganic/organometallic compounds by interpretation of NMR spectra and other analytical data
Dr M Probert
1 Introduction; the basis of crystallographic methods
2 Diffraction of X-rays by molecules and crystals: geometry and symmetry
3 The intensities of diffracted X-rays
4 Crystallography practice: from sample to diffraction pattern
5 Crystallography practice: from diffraction pattern to structure
6 Results and their significance
7 Case studies
8 Powder diffraction 1
9 Powder diffraction 11
10 Solvent inclusion, twinning, disorders and others
Chemical Applications of Symmetry
Dr RJ Errington
1 Review of previous material on symmetry elements, symmetry operations and point groups. Introduction to character tables.
2-3 Irreducible and reducible representations. Symmetry analysis of stretching vibrations of small symmetric molecules; normal modes; IR and Raman activity; determination of molecular shape from vibrational spectra.
4-5 Symmetry properties of atomic orbitals and their combination to give molecular orbitals: ? and ? orbitals of small symmetric molecules; symmetry analysis of d-orbitals in transition metal complexes and the consequences for spectroscopy and other properties.
Dr I Hardcastle
1 Electron Impact Mass Spectrometry
2 Fragmentations in EIMS
3 Alternative 'soft' ionisation methods
4 Applications of MS
5 Applications of MS (seminar)
Course organiser: Dr M Probert
1 Identification of organic compounds from spectroscopic and other data
2 Identification of inorganic compounds from spectroscopic and other data
3 X-ray diffraction: Patterson maps; direct analysis; powder patterns
4 Molecular modelling; the use of the Cambridge Structural Database; molecular symmetry
5 Mass spectrometry including isotope patterns
|Guided Independent Study||Assessment preparation and completion||1||86:20||86:20||Reading of textbooks and practice past paper questions|
|Guided Independent Study||Assessment preparation and completion||5||2:00||10:00||Writing practical reports|
|Guided Independent Study||Assessment preparation and completion||32||0:50||26:40||Revision for end of semester examination|
|Guided Independent Study||Assessment preparation and completion||1||3:00||3:00||End of semester examination|
|Scheduled Learning And Teaching Activities||Lecture||32||1:00||32:00||Problem based learning in classes|
|Scheduled Learning And Teaching Activities||Practical||5||8:00||40:00||5 x 8h Practical sessions take place over 5 weeks which will include peer reviewed exercises|
|Scheduled Learning And Teaching Activities||Workshops||2||1:00||2:00||Seminar|
This course covers the principal methods of structural determination used in modern chemistry.
The basis of the course is the lectures, but these are strongly reinforced by the closely integrated practical work which gives the students valuable personal experience of the most important techniques and how they can be applied in real life situations. The practical also provide a means of continuous assessment, and the tutorials are especially aimed at giving more theoretical backup
The format of resits will be determined by the Board of Examiners
|Practical/lab report||1||M||25||composed of several individual dry lab reports as specified in the practical course handbook|
The dry-lab practical assessed work will permit the student to practise and consolidate the lecture material and also allow the academic subject tutor to monitor progress towards the learning outcomes.
The examination will assess the student's knowledge and understanding of the basic principles of all areas of spectroscopy.
Study Abroad students may request to take their exam before the semester 1 exam period, in which case the format of the paper may differ from that shown in the MOF. Study Abroad students should contact the school to discuss this.