Event Details

IoN Lunch Club: The Mechanism of Trichloroethylene Neurotoxicity and its Relation to Parkinsonism

Paul Keane (Newcastle University)
Venue: Room MED L2.5, Leech Building, Newcastle University
Date: 15th February 2012
Time: 13:00 - 14:00

Parkinson’s Disease (PD) is an age-related, progressive, neurodegenerative condition that is characterised by deterioration of the dopaminergic neurons of the substantia nigra pars compacta (SNpc).  The exact mechanism by which SNpc cell death occurs are poorly understood but is thought to involve both environmental and genetic factors. Trichloroethylene (TCE) is one potential environmental chemical that may contribute to the development of PD and other similar forms of parkinsonism.  In this talk I will present our study into a possible toxic mechanism for TCE in PD.

This item was added 16th December 2011

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