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Publication:

Differential selection of acridine resistance mutations in human DNA topoisomerase II beta is dependent on the acridine structure (2007)

Author(s): Leontiou C, Watters GP, Gilroy KL, Heslop P, Cowell IG, Craig K, Lightowlers RN, Lakey JH, Austin CA

      • Date: 01-04-2007
      • Journal: Molecular Pharmacology
      • Volume: 71
      • Issue: 4
      • Pages: 1006-1014
      • Publisher: American Society for Pharmacology and Experimental Therapeutics
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: METAL-ION MECHANISM NON-CYCLING CELLS CLEAVABLE COMPLEXES DRUG-RESISTANCE POINT MUTATION AMSACRINE ALPHA LEUKEMIA ANTITUMOR DOMAIN

      Staff

      Professor Robert Lightowlers
      Director, ICaMB and Professor of Molecular Neuroscience