I address the question of how the brain works by investigating (i) how the brain is organized anatomically; (ii) what processes go on inside it; (iii) how these processes interact to cause behaviour, particularly visual behaviour; and (iv) what biological constraints must be met by the brain. more recently, I have applied the data-analytic tools developed by my group in these activities to biochemical networks, in the context of drug discovery, targeting and screening. My laboratory was instrumental in developing the neuroinformatics approach - computer-based collation, management, and analysis of neuroscience data.
Dr Robert Robertson, neurophysiology
Dr Kun Guo, neurophysiology
Dr Tom Binzegger, computational neuroscience
Dr Peter Andras, computational neurophysiology
Dr Mark O'Neill, computing support
Dr Sasan Mahmoodi, computing support
Dr Angel Nevado, mathematical neuroscience
Dr Panos Periorellis, complex systems science
Dr Steve Sutton, complex systems science
Dr Olusola Idowu, complex system science
Dr Margaret MacDonald, special projects manager
Dr Joanna Daymond, special projects manager
Maribel Pulgarin-Montoya, mathematical neuroscience
Klaas Stephan, neuroinformatics, PG(R)
Fillippo Petroni, mathematical neuroscience, Wellcome prize student
Anne Threadgold, Personal assistant
Young M.P. "Objective analysis of the topological organization of the primate cortical visual system" Nature 358: 152-155, 1992.
Young M.P., & Yamane S. "Sparse population coding of faces in the inferotemporal cortex" Science 256: 1327-1331, 1992.
Scannell J.W., Blakemore C. & Young M.P. "Analysis of connectivity in the cat cerebral cortex", Journal of Neuroscience 15: 1463-1483, 1995.
Nevado A., Young M.P & Panzeri S. Comparing the information encoded by different brain areas with functional imaging techniques. Lecture notes in Computer Science 2415: 105-110, 2002.
Nevado A., Young M.P & Panzeri S. Functional imaging and neuronal information processing. Neurocomputing 44: 1127-1131, 2002.
Panzeri, S., Golledge HDR., Zheng F., Pola G., Blanche T.J., Tovee, M.J & Young M.P. The role of correlated firing and synchrony in coding infomraion about single and separate objects in cat V1. Neurocomputing 44: 579-584, 2002.
Panzeri S., Pola G., Petroni F., Young M.P. & Peterson R.S. A critical assessment of different measures of the information carried by correlated meuronal firing. BIOSYSTEMS 67 (1-3): 177-185, 2002.
Young M.P & Scannell J.W. "Brain structure-function relationships: advances from neuroinformatics" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 3-6, 2000.
Hilgetag C.C., O'Neill M.A & Young M.P. "Hierarchical organisation of macaque and cat cortical sensory systems explored with a novel network processor" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 71-89, 2000.
Hilgetag C.C., Stephan K., Burns G., O'Neill M.A & Young M.P. "CLustered organisation of cortex and connectivity in macaque monkey and cat" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 91-110, 2000.
Stephan K.E., Hilgetag C.C., Burns, GAPC., O'Neill M.A., Young M.P. & Kotter R. "Computational analysis of global functional connectivity between areas of primate cerebral cortex" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 111-126, 2000.
Burns GAPC. & Young M.P. "Analysis of the connectional organisation of neural systems associated witht eh hippocampus in rats" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 55-70, 2000.
Young M.P., Hilgetag C.C. & Scannell J.W. "On imputing function to structure from the behavioural effects of brain lesions" Philosophical Transactions of the Royal Society: Biological Sciences, 355: 147-161, 2000.
Young M.P " The arcitecture of visual cortex and inferential processes in vision" Spatial Vision 13: 137-146, 2000.
Panzeri S., Golledge HDR., Zheng F., Tovee M.J. & Young M.P. "Objective assessment of the functional role of spike tain correlations using information measures" Visual Cognition, 8: 531-547, 2001.
Petroni F., Panzeri S., Hilgetag C.C. & Young M.P. Simultaneity of responses in a hierachical visual network. NeuroReport, 12: 2753-2759, 2001.
Petroni F., Panzeri S., Hilgetag C.C & Young M.P. Hierarchical organization and neuronal response latencies in the primate visual system. Neurocomputing, 38: 1519-1523, 2001.
Stephan K.E., Kamper L., Bozkurt A., Burns GAPC., Young M.P. & Kotter R. Advanced database methodology for the COllation of Connectivity data on the Macaque brain (CoCoMac). Philosophical Transactions of the Royal Society: Biological Sciences, 356: 1159-1186, 2001.
Golledge HDR., Panzeri S., Zheng F.S., Pola G., Scannell J.W., Giannikopoulos D.V., Mason R.J., Tovee M.J. & Young M.P. Correlations, feature-binding and population coding in primary visual cortex. NeuroReport 14(7):1045-1050, 2003.
Guo K., Robertson R.G., Mahmoodi S., Tadmor Y. & Young M.P. How do subjects view faces? - A study of eye movements. Experimental Brain Reserch 150(3):363-374, 2003.