Newcastle University

Roles and Responsibilities

NHS clinical consultant.

Research within Institute of Neuroscience.

Undergraduate and postgraduate teaching.

Head of Northern Deanery Postgraduate School of Psychiatry.

Qualifications

MB BS
MD(hons)
MRCPsych

Previous Positions

1.7.2000 to 25.8.2002: Academic Specialist Registrar, Department of Psychiatry,Newcastle University.

1.7.98 - 30.6.2000: Clinical Research Associate, Department of Psychiatry, Newcastle University

Memberships

International Society for Bipolar Disorders
British Association for Psychopharmacology
Royal College of Psychiatrists
British Medical Association

Research Interests

Structural neuroimaging in affective disorders; Work including MRI volumetric analysis, white matter structural change, diffusion tensor imaging and MR spectroscopy. Specific clinical areas investigated include early and late onset depression, bipolar affective disorder and relation of structural change to HPA axis abnormalities and vascular risk.

Current Work

Member of psychobiology research group.
Investigation of structural brain change in euthymic patients with bipolar affective disorder: Volumetric change, white matter hyperintensities, white matter tract integrity (diffusion tensor MRI) and MRS.

Co-investigator for the ADD (anti-glucocorticoid augmentation of antidepressants in depression) study: http://www.theaddstudy.co.uk/index.html

Future Research

Development of research in affective disorders with focus on neuroimaging.

Research Roles

Development and implementation of protocols for research in affective disorders, particularly using neuroimaging.

Postgraduate student supervision.

Postgraduate Supervision

Structural neuroimaging in psychiatric disorders

Esteem Indicators

Member of regional committee of Mental Health Foundation - charitable body awarding for research and services in menatal health care.

Undergraduate Teaching

Stage 3 and stage 4 medical student clinical teaching.

 Postgraduate Teaching

MRes(NEU 8002)course teacher

Northern Region MRCPsych course teaching and module leader.

• Vasudev A, Watson S, Harrison CL, Lloyd A, Young AH. Bipolar prescription patterns. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2003, Cambridge, UK: Sage Publications Ltd.
• Lloyd AJ. [abstract] 2 grades, 2 exams, 6 specialties; psychiatric training: UK & Ireland. European Psychiatry 2002, 17(s1), 93S.
• Lloyd AJ, McGuckin EA, Barnett NA, Gholkar A, McKeith IG, Young AH, Ferrier IN, O'Brien JT. Increased salivary cortisol in late- but not early-onset depression: Relationship with hippocampal volume. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2002, Harrogate: Sage Publications Ltd.
• Lloyd A, Harriram H, Thompson JM, Ferrier IN, Young AH, McAllister V, Moore PB. White matter abnormalities in euthymic subjects with bipolar affective disorder. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2002, Harrogate: Sage Publications Ltd.
• Macritchie KAN, Lloyd AJ, Bastin ME, Vasudev K, Gallagher P, Eyre R, Marshall I, Wardlaw JM, Ferrier IN, Moore PB, Young AH. White matter microstructural abnormalities in euthymic bipolar disorder. British Journal of Psychiatry 2010, 196(1), 52-58.
• Lloyd AJ, Moore PB, Cousins DA, Thompson JM, McAllister VL, Hughes JH, Ferrier IN, Young AH. White matter lesions in euthymic patients with bipolar disorder. Acta Psychiatrica Scandinavica 2009,120 6 481-491.
• Curtis VA, Thompson JM, Seal ML, Monks PJ, Lloyd AJ, Harrison L, Brammer MJ, Williams SCR, Murray RM, Young AH, Ferrier IN. The nature of abnormal language processing in euthymic bipolar I disorder: Evidence for a relationship between task demand and prefrontal function. Bipolar Disorders 2007, 9(4), 358-369.
• Vasudev A, Watson S, Lloyd AJ, Harrison CL, Young AH. Bipolar prescription patterns: a cohort follow-up analysis. Quarterly Journal of Mental Health 2006,1 1 .
• Lloyd AJ, Ferrier IN, Barber R, Gholkar A, Young AH, O'Brien JT. Hippocampal volume change in depression: Late- and early-onset illness compared. British Journal of Psychiatry 2004, 184(6), 488-495.
• Monks PJ, Thompson JM, Bullmore ET, Suckling J, Brammer MJ, Williams SCR, Simmons A, Giles N, Lloyd AJ, Harrison CL, Seal M, Murray RM, Ferrier IN, Young AH, Curtis VA. A functional MRI study of working memory task in euthymic bipolar disorder: Evidence for task-specific dysfunction. Bipolar Disorders 2004, 6(6), 550-564.
• Firbank MJ, Lloyd AJ, Ferrier N, O'Brien JT. A volumetric study of MRI signal hyperintensities in late-life depression. American Journal of Geriatric Psychiatry 2004, 12(6), 606-612.
• O'Brien JT, Lloyd A, McKeith I, Gholkar A, Ferrier N. A Longitudinal Study of Hippocampal Volume, Cortisol Levels, and Cognition in Older Depressed Subjects. American Journal of Psychiatry 2004, 161(11), 2081-2090.
• Lloyd AJ, Young AH. Combination therapy in bipolar disorder. In:Kasper, S and Hirschfield, R, ed. Handbook of Bipolar Disorder: Diagnosis and Therapeutic Approaches.London:Taylor & Francis,2005.
• Day E, Grimmer C, Lloyd AJ. Psychiatry training in Europe: a brief history of the European Federation of Psychiatric Trainees. Psychiatric Bulletin 2002, 26(4), 152-154.
• Ahuja N, Lloyd AJ. Aripiprazole and worsening of psychosis: A case report [9]. Journal of Clinical Psychiatry 2007. , 68(5), 805-806.
• Ahuja N, Lloyd A. Self-cannibalism: An unusual case of self-mutilation. Australian and New Zealand Journal of Psychiatry 2007. , 41(3), 294-295.
• Ahuja N, Carroll BT, Lloyd AJ. Catatonia associated with systemic lupus erythematosus. Psychiatry and Clinical Neurosciences 2007. , 61(4), 450-451.
• Ahuja N, Vasudev K, Lloyd A. Hyperprolactinemia and delusion of pregnancy. Psychopathology 2008, 41(1), 65-68.
• Fiorillo A, Carrà G, Hanon C, Lloyd AJ, Ozturk O, Perris F, Vandenberghe J. La Formazione in Psichiatria in diversi Paesi Europei. Studi di Psychiatria 2002, 4(3).
• Macritchie KAN, Gallagher P, Lloyd AJ, Bastin ME, Vasudev K, Marshall I, Wardlaw JM, Ferrier IN, Moore PB, Young AH. Correlations Between Periventricular White Matter Diffusion Parameters and Salivary Cortisol Levels in Euthymic Bipolar Patients and in Control Subjects. In: Biological Psychiatry: 64th Annual Convention of the Society of Biological Psychiatry. 2009, Vancover, Canada: Elsevier Inc..
• Ahuja N, Moorhead SRJ, Lloyd AJ, Cole AJ. Antipsychotic-induced hyperprolactinemia and delusion of pregnancy. Psychosomatics 2008, 49(2), 163-167.
• Ahuja N, Palanichamy N, Mackin P, Lloyd A. Olanzapine-induced hyperglycaemic coma and neuroleptic malignant syndrome: case report and review of literature. Journal of Psychopharmacology 2010, 24(1), 125-130.
• Ahuja N, Lloyd AJ. On catatonia, seizures, and bradycardia. Psychosomatics 2008. , 49(1), 86.
• Armstrong D, Ahuja N, Lloyd AJ. Quetiapine-related dysphagia. Psychosomatics 2008. American Psychiatric Publishing Inc., 49(5), 450-452.
• Vasudev K, Lloyd A, Ahuja N. Repeat prescribing in secondary care: are there any standards?. Psychiatric Bulletin 2008, 32(12), 474.
• Ahuja N, Lloyd AJ. Worsening of psychosis in a 30 year old man with undifferentiated schizophrenia. Annals of Clinical Psychiatry 2008. , 20(2), 113-114.
• Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Suckling J, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Altered functional brain activation during word generation in euthymic bipolar subjects. In: Journal of Affective Disorders: 1st Biennial Conference on International Society for Affective Disorders (ISAD). 2002, Taormina, Sicily: Elsevier BV.
• Middelkoop HAM, Van Der Flier WM, Burton EJ, Lloyd AJ, Paling S, Barber R, Ballard C, McKeith IG, O'Brien JT. Dementia with Lewy bodies and AD are not associated with occipital lobe atrophy on MRI. Neurology 2001, 57(11), 2117-2120.
• Lloyd AJ, Grace JB, Jaros E, Perry RH, Fairbairn AF, Swann AG, O'Brien JT, McKeith IG. Depression in late life, cognitive decline and white matter pathology in two clinico-pathologically investigated cases. International Journal of Geriatric Psychiatry 2001, 16(3), 281-287.
• Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Using fMRI to study euthymic bipolar patients: a new paradigm for investigating language processing. In: Seventh annual meeting of the Organization for Human Brain Mapping. 2001, Brighton, United Kingdom: Academic Press.
• Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Using fMRI to study euthymic bipolar patients: studies of verbal fluency. In: NeuroImage. 2001, Academic Press.