Dr Claudia Racca
Senior Lecturer

  • Email: claudia.racca@ncl.ac.uk
  • Telephone: +44 (0) 191 208 8716
  • Fax: +44 (0) 191 208 5227
  • Address: Institute of Neuroscience
    The Medical School
    Newcastle University
    Framlington Place
    Newcastle upon Tyne
    NE2 4HH
    UK

Roles and Responsibilities

Lecturer
PhD and postdoc supervisor

Qualifications

Laurea in Biological Sciences, Univ of Milan, Italy, Dr
Postgrad AIRC Fellow: Cell biology & Physiology, Univ. of Milan, Italy

Research Interests

1) Investigation of the functional, cellular and molecular mechanisms of synaptic and network activity relevant to glutamate and glycine receptor protein and mRNA localisation in neurons.
2) Characterisation of the physiology and neurochemistry of synchronised neuronal networks in various areas of the central nervous system (e.g. inferior colliculus, hippocampus, cortex and cerebellum). In particular, we aim to identify the key properties of neuronal networks in these areas in order to understand their functional roles in normal and pathological states, with reference to schizophrenia and epilepsy;
3) Neuroanatomical and functional characterisation of gap junctions between neurons within networks. Electrical synapses: their spatial location and regulation with respect to synaptic and neuronal network activity.

The lab research focuses on a multidisciplinary approach: immunocytochemical techniques at the light and electron microscopy levels are combined to electrophysiological experiments.

Current Work

1) Biology and physiology of neurotransmitter receptors, in particular GluRs and GlyRs:
- role of neurotransmitter receptors in synaptic transmission
- targeting of neurotransmitter receptor subunit mRNAs and local protein synthesis in the neuronal dendritic tree
2) Functional and molecular mechanisms responsible for synaptic and neuronal network remodelling,
3) Electrical synapses: their spatial location and regulation with respect to synaptic and neuronal network activity.

Postgraduate Supervision

Neela Codadu (PhD 2013-16) 

Rolando Berlinguer-Palmini (PhD, Univ. of Florence, Italy)

Ryley Parrish (PhD, UBA, USA)

John Grady (PhD 2014) 

Chris Taylor (MRes 2011)

Dorcas Eden (PhD 2009)

Olivia Skrobot (PhD 2008)

Anita Roopun (PhD 2006)

Steven Middleton (PhD 2005)

Normal 0 false false false EN-US JA X-NONE

David Cox (PhD, University College London)