Dr Evelyn Jaros
Honorary Senior Research Associate; Clinical Scientist in Neuropathology
Email: evelyn.jaros@ncl.ac.uk Telephone: +44 (0) 191 282 1300 Address: Neuropathology/Cellular Pathology
Crawford House
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE1 4LP
Lax NZ, Gnanapavan S, Dowson SJ, Alston CL, He LP, Polvikoski TM, Jaros E, O'Donovan DG, Yarham JW, Turnbull DM, Dean AF, Taylor RW. Early-Onset Cataracts, Spastic Paraparesis, and Ataxia Caused by a Novel Mitochondrial tRNA(Glu) (MT-TE) Gene Mutation Causing Severe Complex I Deficiency: A Clinical, Molecular, and Neuropathologic Study .
Journal of Neuropathology and Experimental Neurology 2013, 72 (2), 164-175.
Bogle H, Lax NZ, Jaros E, McFarland R, Taylor RW, Turnbull DM. Neuropathological changes in Alpers' syndrome .
In: 114th Meeting of the British Neuropathological Society: Symposium on Advances in Motor Neuron Diseases . 2013, London: Wiley-Blackwell Publishing Ltd.
Davidson YS, Robinson AC, Hu Q, Mishra M, Baborie A, Jaros E, Perry RH, Cairns NJ, Richardson A, Gerhard A, Neary D, Snowden JS, Bigio EH, Mann DMA. Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes .
Neuropathology and Applied Neurobiology 2013, 39 (2), 157-165.
Mukaetova-Ladinska EB, Andras A, Milne J, Abdel-All Z, Bohr I, Jaros E, Perry RH, Honer WG, Cleghorn A, Doherty J, McIntosh G, Perry EK, Kalaria RN, McKeith IG. Synaptic proteins and choline acetyltransferase loss in visual cortex in dementia with Lewy bodies .
Journal of Neuropathology and Experimental Neurology 2013, 72 (1), 53-60.
Kalaria RN, Perry RH, O'Brien J, Jaros E. Atheromatous disease in small intracerebral vessels, microinfarcts and dementia .
Neuropathology and Applied Neurobiology 2012, 38 (5), 505-508.
Lax NZ, Hepplewhite PD, Reeve AK, Nesbitt V, McFarland R, Jaros E, Taylor RW, Turnbull DM. Cerebellar Ataxia in Patients With Mitochondrial DNA Disease: A Molecular Clinicopathological Study .
Journal of Neuropathology and Experimental Neurology 2012, 71 (2), 148-161.
Baborie A, Griffiths TD, Jaros E, Momeni P, McKeith IG, Burn DJ, Keir G, Larner AJ, Mann DM, Perry R. Frontotemporal Dementia in Elderly Individuals .
Archives of Neurology 2012, 69 (8), 1052-1060.
Baborie A, Jaros E, Griffiths TD, Momeni P, Perry R, Mann DMA. Frontotemporal lobar degeneration in a very young patient is associated with fused in sarcoma (FUS) pathological changes .
Neuropathology and Applied Neurobiology 2012, 38 (1), 101-104.
Lax NZ, Campbell GR, Reeve AK, Ohno N, Zambonin J, Blakely EL, Taylor RW, Bonilla E, Tanji K, DiMauro S, Jaros E, Lassmann H, Turnbull DM, Mahad DJ. Loss of Myelin-Associated Glycoprotein in Kearns-Sayre Syndrome .
Archives of Neurology 2012, 69 (4), 490-499.
Lax NZ, Pienaar IS, Reeve AK, Hepplewhite PD, Jaros E, Taylor RW, Kalaria RN, Turnbull DM. Microangiopathy in the cerebellum of patients with mitochondrial DNA disease .
Brain 2012, 135 (6), 1736-1750.
Krishnan KJ, Ratnaike TE, De Gruyter HLM, Jaros E, Turnbull DM. Mitochondrial DNA deletions cause the biochemical defect observed in Alzheimer's disease .
Neurobiology of Aging 2012, 33 (9), 2210-2214.
Lax NZ, Jaros E. Neurodegeneration in primary mitochondrial disorders .
In: Reeve, A.K., Krishnan, K.J., Duchen, M.R., Turnbull, D.M, ed. Mitochondrial Dysfunction in Neurodegenerative Disorders . Berlin; New York: Springer, 2012, pp.21-42.
Burton EJ, Mukaetova-Ladinska EB, Perry RH, Jaros E, Barber R, O'Brien JT. Neuropathological correlates of volumetric MRI in autopsy-confirmed Lewy body dementia .
Neurobiology of Aging 2012, 33 (7), 1228–1236.
Burton EJ, Mukaetova-Ladinska EB, Perry RH, Jaros E, Barber R, O'Brien JT. Quantitative neurodegenerative pathology does not explain the degree of hippocampal atrophy on MRI in degenerative dementia .
International Journal of Geriatric Psychiatry 2012, 27 (12), 1267-1274.
Reeve AK, Park TK, Jaros E, Campbell GR, Lax NZ, Hepplewhite PD, Krishnan KJ, Elson JL, Morris CM, McKeith IG, Turnbull DM. Relationship Between Mitochondria and α-Synuclein: A Study of Single Substantia Nigra Neurons .
Archives of Neurology 2012, 69 (3), 385-393.
Lax NZ, Whittaker RG, Hepplewhite PD, Reeve AK, Blakely EL, Jaros E, Ince PG, Taylor RW, Fawcett PR, Turnbull DM. Sensory neuronopathy in patients harbouring recessive polymerase γ mutations .
Brain 2012, 135 (1), 62-71.
Mackenzie IRA, Neumann M, Baborie A, Sampathu DM, Du Plessis D, Jaros E, Perry RH, Trojanowski JQ, Mann DMA, Lee VMY. A harmonized classification system for FTLD-TDP pathology .
Acta Neuropathologica 2011, 122 (1), 111-113.
Elstner M, Morris CM, Heim K, Bender A, Mehta D, Jaros E, Klopstock T, Meitinger T, Turnbull DM, Prokisch H. Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death .
Acta Neuropathologica 2011, 122 (1), 803-809.
Baborie A, Griffiths TD, Jaros E, McKeith IG, Burn DJ, Richardson A, Ferrari R, Moreno J, Momeni P, Duplessis D, Pal P, Rollinson S, Pickering-Brown S, Thompson JC, Neary D, Snowden JS, Perry R, Mann DMA. Pathological correlates of frontotemporal lobar degeneration in the elderly .
Acta Neuropathologica 2011, 121 (3), 365-371.
Snowden JS, Hu Q, Rollinson S, Halliwell N, Robinson A, Davidson YS, Momeni P, Baborie A, Griffiths TD, Jaros E, Perry RH, Richardson A, Pickering-Brown SM, Neary D, Mann DMA. The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene .
Acta Neuropathologica 2011, 122 (1), 99-110.
Menon R, Baborie A, Jaros E, Mann D, Ray P, Larner A. What's in a name? Neuronal intermediate filament inclusion disease (NIFID), frontotemporal lobar degeneration-intermediate filament (FTLD-IF) or frontotemporal lobar degeneration-fused in sarcoma (FTLD-FUS)? .
Journal of Neurology, Neurosurgery and Psychiatry 2010.
Religa D, Johnson M, Kalaria R, Jaros E, McKeith IG, Perry R, Court JA, Naslund J, Perry EK. Decreased levels of amyloid beta peptide in the brains of smokers .
In: European Journal of Neurology: 9th Congress of the EFNS . 2005, Athens, Greece: Wiley-Blackwell Publishing Ltd.
Cairns NJ, Perry R, Jaros E, Lowe J, Skellerud K, Duckaerts C, Cruz-Sanchez F, Lantos P. A new dementia: Neurofilament inclusion body dementia .
Journal of Neuropathology and Experimental Neurology 2002, 61 (5), 451 abstract no. 35.
Perry EK, Piggott MA, Johnson M, Ballard CG, McKeith IG, Jaros E, Perry RH. Cholinergic and monoaminergic correlates of clinical symptoms in dementia with Lewy bodies .
In: Mapping the Progress of Alzheimer's and Parkinson's Disease . 2002, Kyoto, Japan: Springer.
Teaktong T, Graham A, Court J, Johnson M, Hall R, Perry E, Perry R, Jaros E. Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: Increased alpha 7 immunoreactivity of astrocytes in Alzheimer's disease .
In: Neurobiology of Aging . 2002, Elsevier Inc.
Johnson M, Court J, Perry E, Kalaria R, McKeith I, Jaros E, Perry R, Naslund J, Religa D. Tobacco use is associated with attenuation of beta-amyloidosis in hippocampus and entorhinal cortex of normal elderly individuals .
In: Neurobiology of Aging . 2002, Elsevier Inc.
Burn DJ, Jaros E. Multiple system atrophy: cellular and molecular pathology .
Molecular Pathology 2001, 54 (6), 419-426.
Jaros E, Burn DJ. The pathogenesis of multiple system atrophy: Past, present, and future .
Movement Disorders 2000, 15 (5), 784-788.