Institute of Neuroscience

Staff Profile

Dr Kirsty McAleese

Research Associate

Background

I work at the Campus for Ageing and Vitality under the supervision of Prof. Johannes Attems. My main research focus is the neuropathological investigation of neurodegenerative diseases, with specialist interests in quantitative assessment and clinico-pathological correlations.


Qualifications

PhD - Newcastle University

Biomedical Sciences (Hons) - Newcastle University

Research

My research focuses on the aetiology of white matter changes in Alzheimer’s disease and normal ageing. Understanding the underlying pathophysiology of white matter changes may have important implications for future diagnosis and therapeutics. Furthermore, I implement post mortem MRI of fixed human brain as a means of white matter assessment; a technique which was validated by my group and collaborators at Newcastle. 

In addition, my group is focused on the use and development of quantitative neuropathological assessment using a novel tissue microarray system to aid the investigation of combined neurodegenerative and cerebrovascular pathologies in the ageing human brain. 

Publications