People - Institute of Neuroscience - Newcastle University

Professor Nicol Ferrier
Professor of Psychiatry

Email: nicol.ferrier@ncl.ac.uk
Telephone: +44 (0) 191 208 1390
Fax: +44 (0) 191 208 1387
Address: Academic Psychiatry and Regional Affective Disorders Service
Newcastle University
Wolfson Research Centre
Campus for Ageing and Vitality
Newcastle upon Tyne
NE4 5PL, UK

Profile
Research
Teaching
Publications

Roles and Responsibilities

Professor of Psychiatry, Hon Consultant Psychiatrist

Qualifications

BSc, MBChB,MRCP, MRCPsych,MD,FRCP, FRCPsych,

Previous Positions

1. House Surgeon to Sir R.B. Wright, Southern General Hospital, Glasgow. August 1974-January 1975.
2. House Physician to Professor E.M. McGirr, Royal Infirmary, Glasgow. February 1975-July 1975.
3. Senior House Officer/Registrar on medical rotation, Stobhill Hospital, Glasgow. August 1975-July 1977.
4. Senior House Officer in Psychiatry, Northwick Park Hospital, Harrow, Middlesex. August 1977-August 1978.
5. Medical Research Council Training Fellow and Honorary Psychiatric Registrar, Clinical Research Centre, Northwick Park Hospital, Harrow, Middlesex. September 1978-August 1981.
6. Wellcome Senior Clinical Research Fellow and Honorary Senior Registrar in Psychiatry. Clinical Research Centre, Northwick Park Hospital, Harrow, Middlesex and Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London. September 1981-March 1984.
7. Medical Research Council Clinical Scientist, MRC Neurochemical Pathology Unit, Newcastle General Hospital; Honorary Consultant Psychiatrist and Lecturer, Department of Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne. April 1984-August 1990.
8. Professor of Psychiatry, Department of Psychiatry, University of Newcastle upon Tyne NE1 4LP. Hon Consultant Psychiatrist, Newcastle, Northumberland and North Tyneside Mental Health NHS Trust. September 1990-to date.

Memberships

Royal College of Psychiatrists,

President, British Association for Psychopharmacology,

Collegium Internationale Neuropsycho Pharmacologicum (C.I.N.P.),

Wellcome Trust Neuroscience and Mental Health Funding Committee.

Research Interests

Professor Ferrier's major research interests are in psychopharmacology and the neurobiology and treatment of severe affective disorders. Professor Ferrier is involved in many areas of grant-supported research and has published over 150 papers. He regularly presents at national and international conferences.

Research Roles

General Secretary British Association for Psychopharmacology.
Member of Research Development Committee, Scottish Office.
Member of MRC Clinical Training Awards Committee.

Undergraduate Teaching

Undergraduate:

Essential junior rotation
Options: 3 offered in treatment resistant depression in a tertiary centre

Senior rotation (Prof. Ferrier is co-ordinator)

Postgraduate Teaching

Postgraduate: Course Director, MRCPsych Course,

Cousins DA, Aribisala B, Ferrier I, Blamire AM. Lithium, Gray Matter, and Magnetic Resonance Imaging Signal. Biological Psychiatry 2013, (epub ahead of print).
Nilsson J, Ferrier IN, Coventry K, Bester A, Finkelmeyer A. Negative BOLD response in the hippocampus during short-term spatial memory retrieval. Journal of Cognitive Neuroscience 2013. In Press.
Watson S, Gallagher P, Porter RJ, Smith MS, Herron LJ, Bulmer S, North-East Mood Disorders Clinical Research Group, Young AH, Ferrier IN. A Randomized Trial to Examine the Effect of Mifepristone on Neuropsychological Performance and Mood in Patients with Bipolar Depression. Biological Psychiatry 2012, 72(11), 943-949.
Watkins HB, Nendick J, Atkinson L, Ferrier IN, Grunze H, Scott J, Meyer TD. Investigating impulsivity in bipolar II disorder: more state than trait?. In: 5th Biennial Conference of the International Society for Bipolar Disorders. 2012, Istanbul, Turkey: Wiley-Blackwell Publishing, Inc.
Nendick J, Watkins H, Atkinson L, Ferrier IN, Grunze H, Meyer T, Scott J. Met and unmet needs: evidence of significant health and social problems in bipolar II disorders from the MRC UK, 'ABC' Cohort study. In: 5th Biennial Conference of the International Society for Bipolar Disorders. 2012, Istanbul, Turkey: Wiley-Blackwell Publishing Ltd.
Sharma A, Barron J, Le Couteur J, Grunze H, Kelly T, Ferrier I, Close A, Rushton S, Le Couteur A. Neurocognitive function in children of adults with bipolar disorder: a UK study. In: Bipolar Disorders: 9th International Conference on Bipolar Disorder. 2011, Pittsburgh, Pennsylvania, USA: Wiley-Blackwell Publishing, Inc.
Harrison PJ, Baldwin DS, Barnes TRE, Burns T, Ebmeier KP, Ferrier IN, Nutt DJ. No psychiatry without psychopharmacology. British Journal of Psychiatry 2011, 199(4), 263-265.
Mackin P, Nulkar A, Waton T, Watkinson HMO. Prolactin and smoking status in antipsychotic-treated patients. Journal of Psychopharmacology 2011, 25(5), 698-703.
Smith FE, Cousins DA, Thelwall P, Ferrier IN, Blamire AM. Quantitative Lithium Magnetic Resonance Spectroscopy in the Normal Human Brain on a 3T Clinical Scanner. Magnetic Resonance in Medicine 2011, 66(4), 945-949.
Sharma A, Neely J, Camilleri N, Grunze H, James A, Ferrier IN, LeCouteur AS. Surveillance of Paediatric bipolar I disorder in the United Kingdom (UK) and the Republic of Ireland (ROI) - results from year 1. In: Bipolar Disorders: 9th International Conference on Bipolar Disorder. 2011, Pittsburgh, Pennsylvania, USA: Wiley-Blackwell Publishing, Inc.
Watson S, Bulmer S, Gallagher P, Svennson LJ, Smith MS, Watkinson HMO, Harikumar TR, Carlile J, Ferrier IN, Young AH. The efficacy of mifepristone in bipolar depression - Effect on mood symptoms. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2011, Harrogate: Sage Publications Ltd.
Watson S, Gallagher P, Herron LJ, Smith MS, Watkinson HMO, Harikumar TR, Carlile J, Young AH, Ferrier IN. The efficacy of mifepristone in bipolar depression - Effect on spatial working memory. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2011, Harrogate: Sage Publications Ltd.
Windfuhr K, Turnbull P, While D, Swinson N, Mehta H, Hadfield K, Hiroeh U, Watkinson H, Dixon C, Flynn S, Thomas S, Lewis G, Ferrier I, Amos T, Skapinakis P, Shaw J, Kapur N, Appleby L. The incidence and associated risk factors for sudden unexplained death in psychiatric in-patients in England and Wales. Journal of Psychopharmacology 2011, 25(11), 1533-1542.
Gallagher P, Gray JM, Watson S, Young AH, Ferrier IN. Visuo-spatial memory in bipolar depression: Neuropsychological and HPA axis correlates. In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2011, Harrogate: Sage Publications Ltd.
Liu Y, Blackwood DH, Caesar S, deGeus EJ, Farmer A, Ferreira MA, Ferrier IN, Fraser C, GordonSmith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, Hoogendijk WJ, Hottenga JJ, Jones L, Jones IR, Kirov G, Lin D, McGuffin P, Moskvina V, Nolen WA, Perlis RH, Posthuma D, Scolnick EM, Smit AB, Smit JH, Smoller JW, StClair D, vanDyck R, Verhage M, Willemsen G, Young AH, Zandbelt T, Boomsma DI, Craddock N, O'Donovan MC, Owen MJ, Penninx BW, Purcell S, Sklar P, Sullivan PF. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Molecular Psychiatry 2010, e-pub ahead of print.
Cousins DA, Moore PB, Watson S, Harrison L, Ferrier IN, Young AH, Lloyd AJ. Pituitary volume and third ventricle width in euthymic patients with bipolar disorder. Psychoneuroendocrinology 2010, 35(7), 1074-1081.
Ferrier IN, Lloyd AJ. Practical Guide to Brain Imaging in Bipolar Disorder . In: Young, AH; Ferrier, IN; Michalak, E, ed. Practical Management of Bipolar Disorders. Cambridge: Cambridge University Press, 2010, pp.194-198.
Grozeva D, Kirov G, Ivanov D, Jones IR, Jones L, Green EK, StClair DM, Young AH, Ferrier N, Farmer AE, McGuffin P, Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Rare Copy Number Variants A Point of Rarity in Genetic Risk for Bipolar Disorder and Schizophrenia. Archives of General Psychiatry 2010, 67(4), 318-327.
Mackay CE, Roddick E, Barrick TR, Lloyd AJ, Roberts N, Crow TJ, Young AH, Ferrier IN. Sex dependence of brain size and shape in bipolar disorder: an exploratory study. Bipolar Disorders 2010, 12(3), 306-311.
Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, Moskvina V, Nikolov I, Hamshere ML, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Norton N, Breen G, StClair D, Collier DA, Young AH, Ferrier IN, Farmer A, McGuffin P, Holmans PA, Donnelly P, Owen MJ, O'Donovan MC. Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Molecular Psychiatry 2010, 15(2), 146-153.
Macritchie KAN, Lloyd AJ, Bastin ME, Vasudev K, Gallagher P, Eyre R, Marshall I, Wardlaw JM, Ferrier IN, Moore PB, Young AH. White matter microstructural abnormalities in euthymic bipolar disorder. British Journal of Psychiatry 2010, 196(1), 52-58.
Thomas AJ, Gallagher P, Robinson LJ, Porter RJ, Young AH, Ferrier IN, O'Brien JT. A comparison of neurocognitive impairment in younger and older adults with major depression. Psychological Medicine 2009, 39(5), 725-733.
Shepherd DJ, Insole LM, McAllister-Williams RH, Ferrier IN. Are specialised affective disorder services useful?. Psychiatric Bulletin 2009, 33(2), 41-43.
Palaniyappan L, Insole L, Ferrier I. Combining antidepressants: A review of evidence. Advances in Psychiatric Treatment 2009, 15(2), 90-99.
Thompson JM, Gray JM, Crawford JR, Hughes JH, Young AH, Ferrier IN. Differential Deficit in Executive Control in Euthymic Bipolar Disordere. Journal of Abnormal Psychology 2009, 118(1), 146-160.
Watson S, Horton K, Bulmer S, Carlile J, Corcoran C, Gallagher P, Ferrier IN. Effect of aspirin on hypothalamic-pituitary-adrenal function and on neuropsychological performance in healthy adults: a pilot study. Psychopharmacology 2009, 205(1), 151-155.
El-Badri S, Ashton H, Ferrier I, Moore P. Family illness history, obstetric complications and age of onset in bipolar patients. Open Neuropsychopharmacology Journal 2009, 2, 11-15.
Hamshere ML, Green EK, Jones IR, Jones L, Moskvina V, Kirov G, Grozeva D, Nikolov I, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Breen G, StClair D, Collier DA, Young AH, Ferrier IN, Farmer A, McGuffin P, Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. British Journal of Psychiatry 2009, 195(1), 23-9.
Gallagher P, Reid KS, Ferrier IN. Neuropsychological functioning in health and mood disorder: Modulation by glucocorticoids and their receptors. Psychoneuroendocrinology 2009, 34(Supplement 1), S196-207.
McAllister-Williams RH, Ferrier IN. Pharmacological management of bipolar affective disorder. Psychiatry 2009, 8(4), 120-124.
McAllister-Williams RH, Ferrier IN. Pharmacological management of unipolar affective disorder. Psychiatry 2009, 8(4), 113-119.
Moore PB, Gupta N, Goswami U, Ferrier IN. Soft neurological signs in the first-degree relatives of subjects with bipolar-1 disorder. In: Bipolar Disorders: 8th International Conference on Bipolar Disorder. 2009, Pittsburgh, Pennsylvania, USA: Wiley-Blackwell Munksgaard.
Sharma AN, Neely J, Le Couteur AS, Grunze H, Nicholls D, James A, Graham P, Lynn R, Scott J, Ferrier IN. Study of pediatric bipolar disorder in UK and ROI: development of a case definition and pilot data from North East England. Bipolar Disorders 2009, 11(Supplement 1), 79 P182.
Ng F, Mammen OK, Wilting I, Sachs GS, Ferrier IN, Cassidy F, Beaulieu S, Yatham LN, Berk M. The International Society for Bipolar Disorders (ISBD) consensus guidelines for the safety monitoring of bipolar disorder treatments. Bipolar Disorders 2009, 11(6), 559-595.
Goswami U, Khastgir U, Sharma AN, Varma A, Gulrajani C, Ferrier IN, Young AH, Gallagher P, Thompson JM, Moore PB. The neurocognitive performance of drug-free and medicated euthymic bipolar patients do not differ. Acta Psychiatrica Scandinavica 2009, 120(6), 456-463.
Lloyd AJ, Moore PB, Cousins DA, Thompson JM, McAllister VL, Hughes JH, Ferrier IN, Young AH. White matter lesions in euthymic patients with bipolar disorder. Acta Psychiatrica Scandinavica 2009, 120(6), 481-491.
Mackin P, Bishop D, Watkinson HM, Ferrier IN. A prospective study of glycaemic status in anti-psychotic-treated patients. Journal of Psychopharmacology 2008, 22(5), 563-566.
Gallagher P, Malik N, Newham J, Young AH, Ferrier IN, Mackin P. Antiglucocorticoid treatments for mood disorders. Cochrane Database of Systematic Reviews 2008, (1), CD005168.
Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, GordonSmith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, VanBeck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics 2008, 40(9), 1056-8.
Anderson IM, Ferrier IN, Baldwin RC, Cowen PJ, Howard L, Lewis G, Matthews K, McAllister-Williams RH, Peveler RC, Scott JL, Tylee A. Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines. Journal of Psychopharmacology 2008, 22(4), 343-396.
Sharma A, Le Couteur AS, Nicholls D, Graham P, Lynn R, Ferrier IN. Paediatric Bipolar Disorder: A Way Forward. British Journal of Psychiatry 2008, 192, 150-152.
Gallagher P, Watson S, Dye CE, Young A, Ferrier IN. Persistent effects of mifepristone (RU-486) on cortisol levels in bipolar disorder and schizophrenia. Journal of Psychiatric Research 2008, 42(12), 1037-1041.
Craddock N, Antebi D, Attenburrow M-J, Bailey A, Carson A, Cowen P, Craddock B, Eagles J, Ebmeier K, Farmer A, Fazel S, Ferrier N, Geddes J, Goodwin G, Harrison P, Hawton K, Hunter S, Jacoby R, Jones I, Keedwell P, Kerr M, Mackin P, McGuffin P, MacIntyre DJ, McConville P, Mountain D, O'Donovan MC, Owen MJ, Oyebode F, Phillips M, Price J, Shah P, Smith DJ, Walters J, Woodruff P, Young A, Zammit S. Wake-up call for British psychiatry. British Journal of Psychiatry 2008, 193(1), 6-9.
Mayoral van Son J, Ferrier IN, Artal J, Vazquez Barquero JL. A survey exploring characteristics of bipolar patients referred to a specialist tertiary centre in UK. In: European Psychiatry. 2007, Madrid, Spain: Elsevier Masson.
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, Evans DM, Leung H-T, Marchini JL, Morris AP, Spencer CCA, Tobin MD, Attwood AP, Boorman JP, Cant B, Everson U, Hussey JM, Jolley JD, Knight AS, Koch K, Meech E, Nutland S, Prowse CV, Stevens HE, Taylor NC, Walters GR, Walker NM, Watkins NA, Winzer T, Jones RW, McArdle WL, Ring SM, Strachan DP, Pembrey M, Breen G, Clair DSt, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Hamshere ML, Holmans PA, Jones IR, Kirov G, Moskivina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Farmer A, Williamson R, McGuffin P, Young AH, Ferrier IN, Ball SG, Balmforth AJ, Barrett JH, Bishop TD, Iles MM, Maqbool A, Yuldasheva N, Hall AS, Braund PS, Dixon RJ, Mangino M, Stevens S, Thompson JR, Bredin F, Tremelling M, Parkes M, Drummond H, Lees CW, Nimmo ER, Satsangi J, Fisher SA, Forbes A, Lewis CM, Onnie CM, Prescott NJ, Sanderson J, Matthew CG, Barbour J, Mohiuddin MK, Todhunter CE, Mansfield JC, Ahmad T, Cummings FR, Jewell DP, Webster J, Brown MJ, Lathrop MG, Connell J, Dominiczak A, Marcano CAB, Burke B, Dobson R, Gungadoo J, Lee KL, Munroe PB, Newhouse SJ, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A, Bruce IN, Donovan H, Eyre S, Gilbert PD, Hilder SL, Hinks AM, John SL, Potter C, Silman AJ, Symmons DPM, Thomson W, Worthington J, Dunger DB, Widmer B, Frayling TM, Freathy RM, Lango H, Perry JRB, Shields BM, Weedon MN, Hattersley AT, Hitman GA, Walker M, Elliott KS, Groves CJ, Lindgren CM, Rayner NW, Timpson NJ, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Hill AVS, Bradbury LA, Farrar C, Pointon JJ, Wordsworth P, Brown MA, Franklyn JA, Heward JM, Simmonds MJ, Gough SCL, Seal S, Stratton MR, Rahman N, Ban M, Goris A, Sawcer SJ, Compston A, Conway D, Jallow M, Rockett KA, Bumpstead SJ, Chaney A, Downes K, Ghori MJR, Gwilliam R, Hunt SE, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Cardin NJ, Ferreira T, Pereira-Gale J, Hallgrimsdottir IB, Howie BN, Su Z, Teo YY, Vukcevic D, Bentley D, Mitchell SL, Newby PR, Brand OJ, Carr-Smith J, Pearce SHS, McGinnis R, Keniry A, Deloukas P, Reveille JD, Zhou X, Sims A-M, Dowling A, Taylor J, Doan T, Davis JC, Savage L, Ward MM, Learch TL, Weisman MH. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics 2007, 39(11), 1329-1337.
Mackin P, Gallagher P, Watson S, Young A, Ferrier IN. Changes in brain-derived neurotrophic factor following treatment with mifepristone in bipolar disorder and schizophrenia. Australian and New Zealand Journal of Psychiatry 2007, 41(4), 321-326.
Thanacoody RHK, Daly AK, Reilly JG, Ferrier IN, Thomas SHL. Factors affecting drug concentrations and QT interval during thioridazine therapy. Clinical Pharmacology and Therapeutics 2007, 82(5), 555-565.
Watson S, Owen BM, Gallagher P, Hearn AJ, Young AH, Ferrier IN. Family history, early adversity and the hypothalamic-pituitary-adrenal (HPA) axis: Mediation of the vulnerability to mood disorders. Neuropsychiatric Disease and Treatment 2007, 3(5), 647-653.
Young AH, Ferrier IN, Ball SG, Mohiuddin MK, Todhunter CE, Mansfield JC, members of the Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447(7145), 661-678.
Thompson JM, Gray JM, Hughes JH, Watson S, Young AH, Ferrier IN. Impaired working memory monitoring in euthymic bipolar patients. Bipolar Disorders 2007, 9(5), 478-489.
Watson S, Gallagher P, Smith MS, Young AH, Ferrier IN. Lithium, arginine vasopressin and the dex/CRH test in mood disordered patients. Psychoneuroendocrinology 2007, 32(5), 464-469.
Mackin P, Bishop D, Watkinson H, Gallagher P, Ferrier IN. Metabolic disease and cardiovascular risk in people treated with antipsychotics in the community. British Journal of Psychiatry 2007, 191, 23-29.
Mackin P, Bishop D, Gallagher P, Watkinson HMO, Ferrier IN. Metabolic disease and cardiovascular risk in psychiatric out-patients taking antipsychotic drugs. In: 62nd Annual Meeting of the Society of Biological Psychiatry. 2007, San Diego, CA: Biological Psychiatry, Elsevier Inc.
Gallagher P, Watson S, Smith MS, Young AH, Ferrier IN. Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder. Schizophrenia Research 2007, 90(1-3), 258-265.
Goswami U, Gulrajani C, Varma A, Sharma A, Ferrier IN, Young AH, Moore PB. Soft neurological signs do not increase with age in euthymic bipolar subjects. Journal of Affective Disorders 2007, 103(1-3), 99-103.
Watson S, Gallagher P, Smith MS, Ferrier IN, Young AH. The dex/CRH test and the DST in patients with bipolar disorder and major depressive disorder. Psychoneuroendocrinology 2007, 32(1), 92-94.
Curtis VA, Thompson JM, Seal ML, Monks PJ, Lloyd AJ, Harrison L, Brammer MJ, Williams SCR, Murray RM, Young AH, Ferrier IN. The nature of abnormal language processing in euthymic bipolar I disorder: Evidence for a relationship between task demand and prefrontal function. Bipolar Disorders 2007, 9(4), 358-369.
Robinson LJ, Thompson JM, Gallagher P, Goswami U, Young AH, Ferrier IN, Moore PB. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. Journal of Affective Disorders 2006, 93(1-3), 105-115.
Thomas AJ, Hendriksen M, Piggott M, Ferrier IN, Perry E, Ince P, O'Brien JT. A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression. Neuropathology and Applied Neurobiology 2006, 32(3), 296-303.
Holmes MK, Gallagher P, Robinson LJ, Gray JM, Olivier P, Heslop P, Ferrier IN. Applications of virtual reality technology in the measurement of spatial memory in patients with mood disorders [2]. CNS Spectrums 2006, 11(6), 417-418.
Young EMW, Ferrier IN. Bipolar affective disorder - an update for primary care. Primary Care and Community Psychiatry 2006, 11(2), 93-96.
Robinson LJ, Ferrier IN. Evolution of cognitive impairment in bipolar disorder: A systematic review of cross-sectional evidence. Bipolar Disorders 2006, 8(2), 103-116.
Thompson JM, Hamilton CJ, Gray JM, Quinn JG, Mackin P, Young AH, Ferrier IN. Executive and visuospatial sketchpad resources in euthymic bipolar disorder: Implications for visuospatial working memory architecture. Memory 2006, 14(4), 437-451.
El-Badri SM, Cousins DA, Parker S, Ashton HC, McAllister VL, Ferrier IN, Moore PB. Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder. British Journal of Psychiatry 2006, 189, 81-82.
Goswami U, Sharma A, Khastigir U, Ferrier IN, Young AH, Gallagher P, Thompson JM, Moore PB. Neuropsychological dysfunction, soft neurological signs and social disability in euthymic patients with bipolar disorder. British Journal of Psychiatry 2006, 188(4), 366-373.
Watson S, Thompson JM, Ritchie JC, Ferrier IN, Young AH. Neuropsychological impairment in bipolar disorder: The relationship with glucocorticoid receptor function. Bipolar Disorders 2006, 8(1), 85-90.
Robinson LJ, Gallagher P, Ferrier IN. Neuropsychological impairment in bipolar disorder: the role of the HPA axis. Aspects of Affect 2006, 1, 92-98.
Ferrier IN, Ferrie LJ, Macritchie KA. Old drug, new data. Advances in Psychiatric Treatment 2006, 12(4), 256-264.
Ferrier N, Macritchie K, Ferrie LJ. Old drug, new data: Revisiting lithium therapy. Advances in Psychiatric Treatment 2006, 12(4), 256-264.
Watson S, Gallagher P, Ferrier IN, Young AH. Post-dexamethasone arginine vasopressin levels in patients with severe mood disorders. Journal of Psychiatric Research 2006, 40(4), 353-359.
Watson S, Gallagher P, Smith MS, Ferrier IN, Young AH. The dex/CRH test-Is it better than the DST?. Psychoneuroendocrinology 2006, 31(7), 889-894.
Gallagher P, Watson S, Smith MS, Ferrier IN, Young AH. Effects of adjunctive mifepristone (RU-486) administration on neurocognitive function and symptoms in schizophrenia. Biological Psychiatry 2005, 57(2), 155-161.
Lamprecht HC, Ferrier IN, Swann AG. The use of ECT in the treatment of depressive illness. London, UK: Royal College of Psychiatrists’ Special Committee on ECT, 2005. The ECT Handbook (2nd ed.): Third Report Council Report CR128.
Ferrier IN. "Torsades de Pointes and Sudden Death". In: P. Haddad, S. Dursun and B. Deakin, ed. Adverse Syndromes and Psychiatric Drugs - A clinical guide. Oxford: Oxford University Press, 2004, pp.51-68.
Monks PJ, Thompson JM, Bullmore ET, Suckling J, Brammer MJ, Williams SCR, Simmons A, Giles N, Lloyd AJ, Harrison CL, Seal M, Murray RM, Ferrier IN, Young AH, Curtis VA. A functional MRI study of working memory task in euthymic bipolar disorder: Evidence for task-specific dysfunction. Bipolar Disorders 2004, 6(6), 550-564.
O'Brien JT, Lloyd A, McKeith I, Gholkar A, Ferrier N. A Longitudinal Study of Hippocampal Volume, Cortisol Levels, and Cognition in Older Depressed Subjects. American Journal of Psychiatry 2004, 161(11), 2081-2090.
Firbank MJ, Lloyd AJ, Ferrier N, O'Brien JT. A volumetric study of MRI signal hyperintensities in late-life depression. American Journal of Geriatric Psychiatry 2004, 12(6), 606-612.
Rendell JM, Juszczak E, Hainsworth J, Van der Gucht E, Healey C, Morriss R, Ferrier N, Young AH, Young H, Goodwin GM, Geddes JR. Developing the BALANCE trial - The role of the pilot study and start-up phase. Bipolar Disorders 2004, 6(1), 26-31.
Gallagher P, Watson S, Smith M, Malik N, Mackin P, Ferrier IN, Young AH. Efficacy of mifepristone (RU-486) in schizophrenia. Acta Psychiatrica Scandinavica 2004, 110(s423), 20.
Thomas AJ, Davis S, Ferrier IN, Kalaria RN, O'Brien JT. Elevation of cell adhesion molecule immunoreactivity in the anterior cingulate cortex in bipolar disorder. Biological Psychiatry 2004, 55(6), 652-655.
Lloyd AJ, Ferrier IN, Barber R, Gholkar A, Young AH, O'Brien JT. Hippocampal volume change in depression: Late- and early-onset illness compared. British Journal of Psychiatry 2004, 184(6), 488-495.
Watson S, Gallagher P, Ritchie JC, Ferrier IN, Young AH. Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder. British Journal of Psychiatry 2004, 184, 496-502.
Young AH, Gallagher P, Watson S, Del-Estal D, Owen BM, Ferrier IN. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology 2004, 29(8), 1538-1545.
Ferrier IN. Introduction to acute mania. In: R.K. Morriss, ed. Managing Acute Mania. London: Science Press, 2004.
Ferrier IN, Chowdhury R, Thompson JM, Watson S, Young AH. Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: A preliminary report. Bipolar Disorders 2004, 6(4), 319-322.
Hendricksen M, Thomas AJ, Ferrier IN, Ince P, O'Brien JT. Neuropathological study of the dorsal raphe nuclei in late-life depression and Alzheimer's disease with and without depression. American Journal of Psychiatry 2004, 161(6), 1096-1102.
Harrison CL, Ferrier N, Young AH. Tolerability of high-dose venlafaxine in depressed patients. Journal of Psychopharmacology 2004, 18(2), 200-204.
Ferrier IN. [abstract] Neuroimaging and psychological findings in bipolar disorder. Journal of Affective Disorders 2004, 78(s1), S7.
Thomas SHL, Ferrier IN. Antipsychotic drug-induced QT interval prolongation. In: Camm, J, ed. Cardiovascular Risk Associated with Schizophrenia and its Treatment. London, UK: Galliard Healthcare Communications, 2003, pp.117-136.
Chowdhury R, Ferrier IN, Thompson JM. Cognitive dysfunction in bipolar disorder. Current Opinion in Psychiatry 2003, 16(1), 7-12.
Almeida OP, Burton EJ, Ferrier N, McKeith IG, O'Brien JT. Depression with late onset is associated with right frontal lobe atrophy. Psychological Medicine 2003, 33(4), 675-681.
McAllister-Williams RH, Ferrier IN. Pharmacological management of unipolar and biploar affective disorder. Psychiatry 2003, 5(3), 77-85.
Watson S, Malik N, Smith MS, Young AH, Ferrier IN. The cortisol response to the DEX/CRH test is stable over time in patients with rapid cycling bipolar disorder (RCBD). In: Journal of Psychopharmacology: Summer Meeting of the British Association for Psychopharmacology. 2003, Cambridge, UK: Sage Publications Ltd.
Lloyd AJ, Harrison CL, Ferrier IN, Young AH. The pharmacological treatment of bipolar affective disorder: Practice is improving but could still be better. Journal of Psychopharmacology 2003, 17(2), 230-233.
Turkington D, Grant JBF, Ferrier IN, Rao NSK, Linsley KR, Young AH. A randomized controlled trial of fluvoxamine in prostatodynia, a male somatoform pain disorder. Journal of Clinical Psychiatry 2002, 63(9), 778-781.
Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Suckling J, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Altered functional brain activation during word generation in euthymic bipolar subjects. In: Journal of Affective Disorders: 1st Biennial Conference on International Society for Affective Disorders (ISAD). 2002, Taormina, Sicily: Elsevier BV.
Thomas AJ, Ferrier IN, Kalaria RN, Davis S, O'Brien JT. Cell adhesion molecule expression in the dorsolateral prefrontal cortex and anterior cingulite cortex in major depression in the elderly. British Journal of Psychiatry 2002, 181(2), 129-134.
Ferrier IN, Thompson JM. Cognitive impairment in bipolar affective disorder: implications for the bipolar diathesis. British Journal of Psychiatry 2002, 180(4), 293-295.
Watson S, Gallagher P, Del-Estal D, Hearn A, Ferrier IN, Young AH. Hypothalamic-pituitary-adrenal axis function in patients with chronic depression. Psychological Medicine 2002, 32(6), 1021-1028.
Lerer B, Segman RH, Fangerau H, Daly AK, Basile VS, Cavallaro R, Aschauer HN, McCreadie RG, Ohlraun S, Ferrier N, Masellis M, Verga M, Scharfetter J, Rietschel M, Lovlie R, Levy UH, Meltzer HY, Kennedy JL, Steen VM, Macciardi F. Pharmacogenetics of tardive dyskinesia: Combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism. Neuropsychopharmacology 2002, 27(1), 105-119.
McAllister-Williams RH, Ferrier IN. Rapid tranquillisation: time for a reappraisal of options for parenteral therapy. British Journal of Psychiatry 2002, 180(6), 485-489.
Reilly JG, Thomas SHL, Ferrier IN. Recent Studies on ECG Changes, Antipsychotic Use and Sudden Death in Psychiatric Patients. Psychiatric Bulletin 2002, 26(3), 110-112.
Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SHL. Thioridazine and sudden unexplained death in psychiatric in-patients. British Journal of Psychiatry 2002, 180, 515-522.
Ferrier N. Treatment-resistant mood disorders. British Journal of Psychiatry 2002, 181(3), 264.
Thomas AJ, Ferrier IN, Kalaria RN, Perry RH, Brown A, O'Brien JT. A neuropathological study of vascular factors in late-life depression. Journal of Neurology Neurosurgery and Psychiatry 2001, 70(1), 83-87.
Macritchie KAN, Ferrier IN. Bipolar affective disorder and anticonvulsant mood stabilizers. International Journal of Psychiatry in Clinical Practice 2001, 7(2), 49-53.
Moore PB, Shepherd D, Eccleston DJ, McMillan IA, Goswami U, McAllister VL, Ferrier IN. Cerebral white matter lesions in bipolar affective disorder: relationship to outcome. British Journal of Psychiatry 2001, 178(2), 172-176.
Ferrier IN. Characterizing the ideal antidepressant therapy to achieve remission. Journal of Clinical Psychiatry 2001, 62(Suppl. 26), 10-15.
O'Brien J, Thomas A, Ballard C, Brown A, Ferrier N, Jaros E, Perry R. Cognitive impairment in depression is not associated with neuropathologic evidence of increased vascular or Alzheimer-type pathology. Biological Psychiatry 2001, 49(2), 130-136.
Ferrier IN. Developments in mood stabilisers. British Medical Bulletin 2001, 57(1), 179-192.
El-Badri SM, Ashton CH, Moore PB, Marsh VR, Ferrier IN. Electrophysiological and cognitive function in young euthymic patients with bipolar affective disorder. Bipolar Disorders 2001, 3(2), 79-87.
Thompson JM, Monks PJ, Lloyd PJ, Harrison CL, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Curtis VA, Young AH. Functional MRI of verbal working memory in prospectively verified euthymic bipolar patients. In: NeuroImage. 2001, Academic Press.
Goswami U, Sharma AN, Khastgir U, Thompson JM, Moore PB, Young AH, Ferrier, symptomatically IN2001NeurocognitivestatusintheimprovedBipolarPatients. Journal of Psychopharmacology. 2001, (15 (Suppl):A66).
Owen BM, Eccleston D, Ferrier IN, Young H. Raised levels of plasma interleukin-1β in major and postviral depression. Acta Psychiatrica Scandinavica 2001, 103(3), 226-228.
Ferrier IN, MacMillan IC, Young AH. The search for the wandering thymostat: A review of some developments in bipolar disorder research. British Journal of Psychiatry 2001, 178(141), s103-s106.
Porter R, Linsley K, Ferrier N. Treatment of severe depression - Non-pharmacological aspects. Advances in Psychiatric Treatment 2001, 7(2), 117-124.
Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Using fMRI to study euthymic bipolar patients: a new paradigm for investigating language processing. In: Seventh annual meeting of the Organization for Human Brain Mapping. 2001, Brighton, United Kingdom: Academic Press.
Monks PJ, Thompson JM, Lloyd AJ, Harrison CL, Bullmore ET, Brammer MJ, Williams SCR, Simmons A, Murray RM, Ferrier IN, Young AH, Curtis VA. Using fMRI to study euthymic bipolar patients: studies of verbal fluency. In: NeuroImage. 2001, Academic Press.
Moore PB, El-Badri SM, Cousins D, Shepherd DJ, Young AH, McAllister VL, Ferrier IN. White matter lesions and season of birth of patients with bipolar affective disorder. American Journal of Psychiatry 2001, 158(9), 1521-1524.
Scott J, Stanton B, Garland A, Ferrier IN. Cognitive vulnerability in patients with bipolar disorder. Psychological Medicine 2000, 30(2), 467-472.
Thomas AJ, Ferrier IN, Kalaria RN, Woodward SA, Ballard C, Oakley A, Perry RH, O'Brien JT. Elevation in late-life depression of intercellular adhesion molecule-1 expression in the dorsolateral prefrontal cortex. United States: American Psychiatric Association, 2000. American Journal of Psychiatry.
Thomas AJ, Ferrier IN, Kalaria RN, Woodward SA, Ballard C, Oakley A, Perry RH, O'Brien JT. Elevation in late-life depression of intercellular adhesion molecule-1 expression in the dorsolateral prefrontal cortex. American Journal of Psychiatry 2000, 157(10), 1682-1684.
Ferrier IN, Calabrese JR. Lamotrigine, Gabapentin and the new anticonvulsants: efficacy in mood disorders. In: Buckley, PF;Waddington, JL, ed. Schizophrenia and Mood Disorders: The New Drug Therapies in Clinical Practice. Oxford: Butterworth/Heinmann, 2000, pp.190-198.
Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SHL. QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet 2000, 355(9209), 1048-1052.
Appleby L, Thomas S, Ferrier N, Lewis G, Shaw J, Amos T. Sudden unexplained death in psychiatric in-patients. British Journal of Psychiatry 2000, 176, 405-406.
Porter RJ, Ferrier IN, Ashton CH. Anticonvulsants as mood stabilisers. Advances in Psychiatric Treatment 1999, 5(22), 96-103.
Porter RJ, Ferrier IN. Emergency Treatment of Depression. Advances in Psychiatric Treatment 1999, 5(1), 3-10.
Porter R, Ferrier IN. Emergency treatment of depression. In: A. Lee, ed. Affective and Non-Psychotic Disorders (Recent topics from Advances in Psychiatric Treatment). London: The Royal College of Psychiatrists, 1999, pp.32-39.
Ferrier IN, Tyrer SP, Bell AJ. Lithium therapy. In: A. Lee, ed. Affective and Non-Psychotic Disorders (Recent topics from Advances in Psychiatric Treatment). London: The Royal College of Psychiatrists, 1999, pp.76-83.
Ferrier N, Vieta E, Heffner T. Neurobiology of bipolar disorder: Relevance to treatment. In: Anticonvulsants in Psychiatry. 1999, Barcelona, Spain: Royal Society of Medicine Press.
Ferrier IN, Stanton BR, Kelly TP, Scott J. Neuropsychological function in euthymic patients with bipolar disorder. British Journal of Psychiatry 1999, 175(3), 246-251.
Ferrier IN. Treatment of major depression: Is improvement enough?. In: Goal of Antidepressant Therapy: Response or Remission and Recovery?. 1999, Glasgow, Scotland: Physicians Postgraduate Press, Inc.
Ferrier IN. Lamotrigine and gabapentin - Alternatives in the treatment of bipolar disorder. Neuropsychobiology 1998, 38, 192-197.
Goswami U, Basu S, Khastgir U, Kumar U, Chandrasekaran R, Gangadhar BN, Sagar R, Bapna JS, Channabasavanna SM, Moore PB, Ferrier IN. Neurobiological characterisation of bipolar affective disorders: A focus on tardive dyskinesia and soft neurological signs in relation to serum dopamine beta hydroxylase activity. Indian Journal of Psychiatry 1998, 40(3), 201-211.
Dahabra S, Ashton CH, Bahrainian M, Britton PG, Ferrier IN, McAllister V, Marsh VR and Moore PB. Structural and functional abnormalities in elderly patients clinically recovered from early- and late-onset depression. Biological Psychiatry 1998, 44, 34-46.
Whatley SA, Curti D, Das Gupta F, Ferrier IN, Jones S, Taylor C, Marchbanks RM. Superoxide, neuroleptics and the ubiquinone and cytochrome b(5) reductases in brain and lymphocytes from normal and schizophrenic patients. Molecular Psychiatry 1998, 3, 227-237.
Ferrier IN and Scott J. The causes of depression. Seminars in General Adult Psychiatry 1998, 102-153.
Scott J, Harrington J, House R, Ferrier IN. Preliminary study of the relationship among personality, cognitive vulnerability, symptom profile, and outcome in major depressive disorder. Journal of Nervous and Mental Disease 1996, 184, 503-505.
Serfaty MA, Martin LM, Lingham R, Ferrier IN. The effect of psychotropic medication on seizure duration during bilateral electroconvulsive therapy: A retrospective study. Journal of Psychopharmacology 1996, 10(4), 303-308.

Newcastle University

Institute of Neuroscience

Professor Nicol Ferrier Professor of Psychiatry