Dr Peter Thelwall
William Leech Reader in Magnetic Resonance Physics

  • Email: pete.thelwall@ncl.ac.uk
  • Telephone: +44 (0) 191 208 1156
  • Fax: +44 (0) 191 208 1151
  • Personal Website: http://www.ncl.ac.uk/magres
  • Address: Newcastle Magnetic Resonance Centre
    Newcastle University
    Campus for Ageing & Vitality
    Newcastle upon Tyne
    NE4 5PL

Background

Undergraduate: BSc - Biochemistry and biological chemistry, Nottingham University, 1995
Postgraduate: PhD - Biochemistry and magnetic resonance. Cambridge University, 1999
Postdoc: Department of Neuroscience, University of Florida. 2000 - 2006

Research Interests

My research focuses on the use of magnetic resonance imaging and spectroscopy to non-invasively monitor changes in tissue metabolic status and function. This encompasses the following projects:
  • Oxidative stress: development of novel techniques to image tissue glutathione content and metabolism
  • Non-invasive in vivo measurement of tissue glycogen content and lipid composition by 1H and 13C spectroscopy
  • Dynamic contrast-enhanced imaging of pulmonary vascular properties: application to clinical research
  • Measurement of lung respiratory function using 19F MRI of inert tracer gases
  • Development and application of methods for non-invasive investigation of diabetic kidney disease

These projects centre on the development of cutting-edge MR methodology, and application of these methods to pre-clinical models and/or clinical studies to investigate the changes in biochemistry, physiology and function associated with disease.

Grant funding

  • MRC New Investigator Research Grant: In vivo monitoring of liver oxidative stress by magnetic resonance measurements of glutathione turnover. 2009-2012

Newcastle Magnetic Resonance Centre

I am a member of the Magnetic Resonance Physics Team at the Newcastle Magnetic Resonance Centre, our research focuses on the application of cutting-edge MR imaging and spectroscopy methods to clinical research. We have a Philips 3T Achieva whole-body scanner equiped with multinuclear (13C, 31P, etc) capability, and a Varian 7T pre-clinical MR system.

PhD supervision: Biomedical Magnetic Resonance Research

Current PhD projects: "Fluorocarbon gases as an MRI contrast agent for measurement of lung ventilation properties"


NHS - Modernising Scientific Careers: Clinical Sciences MSc

Course contributor and Lecturer to the "Medical Physics: Imaging with Non-ionising Radiation" MSc module.