Dr Sarah Richardson
Alzheimer's Society Clinician Tr Fellow
- Email: firstname.lastname@example.org
- Telephone: 01912081314
- Address: Institute of Neuroscience
3rd floor Biomedical Research Building
Campus for Ageing and Vitality
Newcastle upon Tyne
I am a Geriatric Medicine Trainee in the Northern Deanery. I am currently spending 3 years out of programme completing a PhD funded by an Alzheimer's Society Clinician Training Fellowship. My research interests are delirium and dementia. More information about my study can be found under the 'Research' tab. I also hold an Honorary Clinical Contract with Newcastle-upon-Tyne Hospitals NHS Foundation Trust.
MBBS MRes MClinRes MRCP
DECIDE: DElirium and Cognitive Impact in DEmentia
Delirium is a medical word used to describe a change in brain function which makes a person become suddenly confused. Their attention, behaviour and concentration may also be affected. The symptoms can come on quickly and change from hour to hour.
Delirium is common, particularly among people with dementia, older people and those in hospital. Delirium usually gets better within a few days to weeks. However, there is some evidence that delirium may cause permanent damage to the brain. It may make people more likely to develop dementia in the future. In people with dementia, it may make their dementia worse. Unfortunately, we do not understand these effects of delirium very well.
Previous work has shown there are ways we can prevent some cases of delirium or make the problem get better faster.
This study aims to understand more about delirium and the effect it has on dementia because it may be a cause of dementia we can reduce or prevent.
The people to be approached are part of a larger dementia study called the Cognitive Function and Ageing Study-II (CFAS-II). They have regular memory tests. If any of these people come into hospital during the study they will be tested for delirium. They will be monitored for delirium during their hospital stay. They will be seen at home one year later for a memory test to see whether their memory has got worse. The before and after memory tests of those with and without delirium will be compared.
This study will increase our knowledge of delirium and the effect it has on dementia. In the future, preventing delirium may be an important part of dementia prevention.
Click on the following link to read more about my study: http://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=2984
- Jackson TA, Wilson D, Richardson S, Lord JM. Predicting outcome in older hospital patients with delirium:a systematic literature review. International Journal of Geriatric Psychiatry 2016, 31(4), 392-399.
- Cunningham EL, Richardson S, ORegan N, Jackson TA. Delirium – contemporary cultural references: A truth stranger than fiction?. Annals of Delirium Care 2015, 15, 2-5.
- Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, MacLullich AMJ, Meagher D, Brayne C, Timmons S, Davis D. Validation of a Consensus Method for Identifying Delirium from Hospital Records. PLoS One 2014, 9(11), e0111823.
- Richardson S, Isaacs JD. Novel immunotherapies for rheumatoid arthritis. Clinical Medicine 2013, 13(4), 391-394.
- Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens C, Young DA, Isaacs JD. A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly anti-citrullinated peptide antibody-negative disease. Annals of the Rheumatic Diseases 2012, 71(8), 1374-1381.
- Pratt AG, Swan D, Richardson S, Wilson G, Hilkens C, Young D, Isaacs JD. A Transcriptional Profile Present in CD4+T-Cells of Patients with Undifferentiated Arthritis Predicts the Future Development of Seronegative Rheumatoid Arthritis and Implicates IL-6 in Disease Evolution. In: Arthritis & Rheumatism: 75th Annual Scientific Meeting of the American College of Rheumatology. 2011, Chicago, Illinois, USA: John Wiley & Sons, Inc.
- Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens CMU, Young DA, Isaacs JD. Peripheral Blood CD4 T Cell Gene Expression Profiles as Predictive Biomarkers in Early Arthritis. In: 30th European Workshop for Rheumatology Research. 2010, Bamberg, Germany: BMJ Group.
- Davis D, Richardson SJ, Hornby J, Bowden H, Hoffmann K, Weston-Clarke M, Green F, Chaturvedi N, Hughes A, Kuh D, Sampson E, Mizoguchi R, Cheah KL, Romain M, Sinha A, Jenkin R, Brayne C, MacLullich A. The delirium and population health informatics cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population. BMC Geriatrics 2018, 18, 45.
- Richardson SJ, Davis DHJ, Bellelli G, Hasemann W, Meagher D, Kreisel SH, MacLullich AMJ, Cerejeira J, Morandi A. Detecting delirium superimposed on dementia: diagnostic accuracy of a simple combined arousal and attention testing procedure. International Psychogeriatrics 2017, Epub ahead of print.
- Richardson SJ, Davis DHJ, Stephan B, Robinson L, Brayne C, Barnes L, Parker S, Allan LM. Protocol for the Delirium and Cognitive Impact in Dementia (DECIDE) study: A nested prospective longitudinal cohort study. BMC Geriatrics 2017, 17(1), 98.
- Morandi A, Davis D, Bellelli G, Arora RC, Caplan GA, Kamholz B, Kolanowski A, Fick DM, Kreisel S, MacLullich A, Meagher D, Neufeld K, Pandharipande PP, Richardson S, Slooter AJC, Taylor JP, Thomas C, Tieges Z, Teodorczuk A, Voyer P, Rudolph JL. The Diagnosis of Delirium Superimposed on Dementia: An Emerging Challenge. Journal of the American Medical Directors Association 2017, 18(1), 12-18.
- Richardson S, Teodorczuk A, Bellelli G, Davis DHJ, Neufeld KJ, Kamholz BA, Trabucchi M, MacLullich AMJ, Morandi A. Delirium superimposed on dementia: a survey of delirium specialists shows a lack of consensus in clinical practice and research studies. International Psychogeriatrics 2016, 28(5), 853-861.
- Kane JPM, Richardson S, Allan L, Thomas A. Diagnosing dementia. British Journal of Hospital Medicine 2016, 77(2), C22-C25.
- Jenkin RPL, Al-Attar A, Richardson S, Myint PK, MacLullich AMJ, Davis DHJ. Increasing delirium skills at the front door: results from a repeated survey on delirium knowledge and attitudes. Age and Ageing 2016, 45(4), 517-522.
- Richardson SJ, Fisher JM, Teodorczuk A. The Future Hospital: a blueprint for effective delirium care. Future Hospital Journal 2016, 3(3), 178-181.