Defining the prevalence of autonomic dysfunction and its consequences in ME/CFS - a clinical cohort study.

Project Leader(s): Professor Julia Newton
Sponsors: Funded by: ME Research UK-charity


Chronic fatigue syndrome (CFS) is a common condition that frequently impacts upon quality of life.  There is no known cause and currently no effective treatment. We have shown that those with CFS have abnormalities of autonomic nervous system function and muscle bioenergetics.
The purpose of this study is to perform a series of linked studies to examine the pathogenesis of CFS in appropriate phenotypes of those with the diagnosis of CFS. These studies will be specifically designed to assess:

a) Muscle bioenergetics - using state of the art MR spectroscopy techniques.

b) Structural and functional brain abnormalities - using MR.

Staff Profile: Professor Julia Newton