Project:
The effect of a fitness and mobility exercise programme on glucose control and blood flow in the brain in older adults with chronic stroke.
Project Leader(s): Dr M I Trenell and Sarah Moore
Sponsors: Funded by the MRC
Low physical activity and fitness levels following stroke can lead to poor glucose control, decreased cerebral blood flow and an increased risk of further stroke. Exercise interventions have been shown to improve physical fitness and glucose control following stroke but the effect of exercise on cerebral blood flow has yet to be investigated. The aim of this study is to determine whether an exercise intervention will improve cerebral blood flow and glucose control following stroke. Participants in the intervention group will undertake a 19 week programme of fitness and mobility exercise while the control group will complete a stretching programme for a matched period. Alongside tests of glucose control, non-invasive magnetic resonance neuroimaging will be used pre and post intervention to determine whether exercise leads to alterations in cerebral blood flow and brain structure and function.
Staff Profiles: Dr M I Trenell and Sarah Moore
