Newcastle University

Publications from the Magnetic Resonance Centre

(Click on author's name underlined to obtain paper)

Year 2013

• Thelwall PE, Smith FE, Leavitt MC, Canty D, Hu W, Hollingsworth KG, Thoma C, Trenell MI, Taylor R, Rutkowski JV, Blamire AM, Quinn AG.Hepatic Cholesteryl Ester Accumulation in Lysosomal Acid Lipase Deficiency: Non-invasive Identification and Treatment Monitoring by Magnetic Resonance. J Hepatol. 2013 Apr 25. pii: S0168-8278(13)00270-5. doi: 10.1016/j.jhep.2013.04.016. [Epub ahead of print]
  
• Steven S, Lim EL, Taylor R. Population response to information on reversibility of Type 2 diabetes. Diabet Med. 2013 Apr;30(4):e135-8. doi: 10.1111/dme.12116.
• Cousins DA, Aribisala B, Nicol Ferrier I, Blamire AM. Lithium, gray matter, and magnetic resonance imaging signal. Biol Psychiatry. 2013 Apr 1;73(7):652-7. doi: 10.1016/j.biopsych.2012.09.029. Epub 2012 Nov 16.
  
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic D, Macgowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. J Hepatol. 2012 Nov 22. pii: S0168-8278(12)00884-7. doi: 10.1016/j.jhep.2012.11.015. [Epub ahead of print]
  
• Sinha A, Hollingsworth KG, Ball S, Cheetham T. Improving the vitamin d status of vitamin d deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle.
  J Clin Endocrinol Metab. 2013 Mar;98(3):E509-13. doi: 10.1210/jc.2012-3592. Epub 2013 Feb 7.
  
• Duncan GW, Firbank MJ, O'Brien JT, Burn DJ. Magnetic resonance imaging: A biomarker for cognitive impairment in Parkinson's disease? Mov Disord. 2013 Feb 28. doi: 10.1002/mds.25352. [Epub ahead of print] PubMed PMID: 23450518.
• Ford AH, Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, Burn DJ, O'Brien JT.Rapid eye movement sleep behavior disorder in Parkinson's disease: Magnetic resonance imaging study. Mov Disord. 2013 Feb 28. doi: 10.1002/mds.25367. [Epubahead of print] PubMed PMID: 23450684.
  
• He J, Hollingsworth KG, Newton JL, Blamire AM. Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation. NeuroImage 2013, Volume 2, 168-173.
• Bohr IJ, Kenny E, Blamire A, O'Brien JT, Thomas A, Richardson J, Kaiser M. Resting-state functional connectivity in late-life depression: higher global connectivity and more long distance connections. Front. Psychiatry, Jan. 2013, doi: 10.3389/fpsyt.2012.00116
• O'Donovan J, Watson R, Colloby SJ, Firbank MJ, Burton EJ, Barber R, Blamire AM, O'Brien JT.  Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging? Int Psychogeriatr. 2013 Jan;25(1):111-9. doi: 10.1017/S1041610212001214. Epub 2012 Jul 19
• Tryambake D, He J, Firbank MJ, O’Brien JT, Blamire AM, Ford GA. Intensive Blood Pressure Lowering increases Cerebral Blood Flow in Older Subjects with Hypertension. Hypertension, in press (2013).
• Hollingsworth KG, Willis TA, Bates MG, Dixon BJ, Lochmüller H, Bushby K, Bourke J, Macgowan GA, Straub V. Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I. Eur J Heart Fail. 2013 Apr 10. [Epub ahead of print]
  
  

Year 2012

• Wood JS, Firbank MJ, Mosimann UP, Barber R, Watson R, Blamire AM, O’Brien JT. Testing visual perception in dementia with Lewy bodies and Alzheimer’s disease. American Journal of Geriatric Psychiatry 2011; 24:73-83
• Lim EL, Hollingsworth KG, Smith F, Thelwall PE, Taylor R. Effects of raising muscle glycogen synthesis on skeletal muscle ATP turnover rate in type 2 diabetes. American J Physiology 2011 PMID 21917633
• Lim EL, Hollingsworth KG, Aribisala, BS, Chen MJ, Mathers, JC, Taylor R, Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia 2011; 54: 2506-2514.
• Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Mitra D, O'Brien JT. Diffusion tensor imaging in Alzheimer's disease and dementia with Lewy bodies. Psychiatry Res. 2011 194(2):176-83
• Thelwall PE, Taylor R, Marshall SM. Non-invasive investigation of kidney disease in Type 1 diabetes by magnetic resonance imaging. Diabetologia 2011; 54(9):2421-9
• Colloby SJ, Firbank MJ, Vasudev A, Parry SW, Thomas AJ, O'Brien JT. Cortical thickness and VBM-DARTEL in late-life depression. J Affect Disord. 2011; 133(1-2):158-64
• Aribisala BS, He J, Blamire AM. Comparative Study of Standard Space and Real Space Analysis of Quantitative MR Brain Data. Journal of Magnetic Resonance in Imaging 2011;33(6):1503-9
• Smith FE, Cousins DA, Thelwall PE, Ferrier IN, Blamire AM. Quantitative Lithium Magnetic Resonance Spectroscopy in the Normal Human Brain on a 3T Clinical Scanner. Magnetic Resonance in Medicine 2011; 66(4):945-9
• Chalmers KH, Kenwright AM, Parker D, Blamire AM. 19F-lanthanide complexes with increased sensitivity for 19F-MRI: Optimization of the MR acquisition. Magn Reson Med. 2011; 66(4):931-6
• Mardini H, Smith FE, Record C, Blamire AM. Magnetic resonance quantification of water and metabolites in the brain of cirrhotics following induced hyperammonaemia. J Hepatol. 2011; 54: 1154-1160
• Wood J, Firbank MJ, Mosimann UP, Taylor J-P, O’Brien JT. Development of a novel fMRI compatible visual perception prototype battery to test older people with and without dementia. Journal of Geriatric Psychiatry and Neurology 2011; 24(2) 73-83.
• Firbank MJ, He Jiabao, Blamire AM, Singh B, Danson P, Rajesh N. Kalaria, et al. Cerebral blood flow by arterial spin labelling in post stroke dementia. Neurology 2011; 76: 1478-1484
• Lim EL, Hollingsworth KG, Smith F, Thelwall PE, Taylor R. Inhibition of lipolysis in type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates. Clin. Sci. 2011; 121: 169-177
• Yu-Wai-Man P, Trenell MI, Hollingsworth KG, Griffiths PG, PF. C. OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy Brain. 2011; Apr;134(Pt 4):e164.Epub 2010 Oct 14
• Kinali M, Arechavala-Gomeza V, Cirak S, Glover A, Guglieri M, Feng L, Hollingsworth KG, Hunt D, Junbluth H, Roper HP, Quinlivin RM, Gosalakkal JA, Jayawant S, Nadeau A, Hughes-Carre L, Manzur AY, Mercuri E, Morgan JE, Straub V, Bushby K, Sewry C, Rutherford M, Muntoni F. Muscle histology va MRI in Duchenne muscular dystrophy. Neurology. 2011 Jan 25;76(4):346-53.
• Marcos AL, Firbank MJ Widdrington M, Blamire AM, Kalaria RN, O’Brien JT.  Post-stroke dementia: the contribution of thalamus and basal ganglia changes. Int Pyschogeriatrics, in press (2011).
• Hollingsworth KG, Lim EL, Coombs A, Taylor R. Reproducibility of liver and pancreatic fat measurement in type 2 diabetes and normal subjects using the 3 point Dixon technique. Submitted 2011.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R ,Day CP, Trenell MI. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Hepatology Gut 2011;60:1278e1283. doi:10.1136/gut.2011.242073
• Colloby SJ, Firbank MJ, He J, Thomas AJ, Vasudev A, Parry SW, O'Brien JT. Regional cerebral blood flow in late-life depression: arterial spin labelling magnetic resonance study. Br J Psychiatry. 2012 Feb;200(2):150-5. Epub 2011 Dec 22. PubMed PMID: 22194184.
• Smart SD, Firbank MJ, O'Brien JT. Validation of automated white matter hyperintensity segmentation. J Aging Res. 2011;2011:391783. Epub 2011 Sep 6. PubMed PMID: 21904678; PubMed Central PMCID: PMC3167190.
• Colloby SJ, Vasudev A, O'Brien JT, Firbank MJ, Parry SW, Thomas AJ. Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression. Br J Psychiatry. 2011. Nov;199(5):404-10. Epub 2011 Sep 8. PubMed PMID: 21903666.
• Colloby SJ, Firbank MJ, Thomas AJ, Vasudev A, Parry SW, O'Brien JT. White matter changes in late-life depression: a diffusion tensor imaging study. J Affect Disord. 2011 Dec;135(1-3):216-20. Epub 2011 Aug 20. PubMed PMID: 21862137.
• Klein A, Jungbluth H, Clement E, Lillis S, Abbs S, Munot P, Pane M, Wraige E, Schara U, Straub V, Mercuri E and Muntoni F. Muscle Magnetic Resonance Imaging in Congenital Myopathies Due to Ryanodine Receptor Type 1 Gene Mutations, Archives of Neurology, 2011, 68(9), pp. 1171-1179.
  
  

Year 2010

• Hayes L, Pearce MS, Firbank MJ, Walker M, Taylor R, Unwin N. Do obese but metabolically normal women differ in intra-abdominal fat and physical activity levels from those with the expected metabolic abnormalities? A cross-sectional study. BMC Public Health. 2010; 10:723.
• Steven S, Lim EL, Taylor R. Reversal of type 2 diabetes. Diabetic Medicine 2010; 27: 724-725
• Balasubramanian R, Gerrard J, Dalla Man C, Firbank MJ, Lane A, English PT, Cobelli C, Taylor R. Combination peroxisome proliferator-activated receptor gamma and alpha agonist treatment in type 2 diabetes prevents the beneficial pioglitazone effect on liver fat content. Diabetic Medicine 2010; 27:150-156.
• Chen MJ, Jovanovic A, Taylor R. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010; 2552-54.
• Aribisala BA, Cowie CJA, He J, Wood J, Mendelow AD, Mitchell P, Blamire AM. Multi-parametric Classification of Traumatic Brain Injury Patients Using Automatic Analysis of Quantitative MRI Scans. Lecture Notes in Computer Science 2010; 6326: 51-59.
• Firbank MJ, Narayan SK, Saxby BK, Ford GA, JT OB. Homocysteine is associated with hippocampal and white matter atrophy in older subjects with mild hypertension International Psychogeriatrics. 2010; 22(5):804-11.
• Newton J, Hollingsworth K, Taylor R, Blamire A, DE J. Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis. J Hepatol 2010; 53(1):155-61.
• Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Burton EJ, Mitra D, O’Brien JT. High resolution imaging of the medial temporal lobe in Alzheimer’s disease and dementia with Lewy bodies. J Alz Disease 2010; 21: 1129-1140.
• Hollingsworth KG, Jones DEJ, Taylor R, Frith J, Blamire AM, Newton JL. Impaired cerebral autoregulation in primary biliary cirrhosis: implications for the pathogenesis of cognitive decline. Liver International. 2010; 30:878-85.
• Hollingsworth KG, Jones DEJ, Taylor R, Blamire AM, Newton JL. Impaired cardiovascular response to standing in chronic fatigue syndrome. European Journal of Clinical Investigation. 2010; 40(7):608-15.
• Hollingsworth KG, Newton JL, Robinson L, Taylor R, Blamire AM, Jones DE. Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in Primary Biliary Cirrhosis J Hepatol 2010; 53:155-161
• Kenny ER, O’Brien JT, Cousins D, Richardson J, Thomas A, Firbank MJ, Blamire AM. Functional Connectivity in Late-life Depression using Resting-state Functional Magnetic Resonance Imaging. Am J Geriatric Psychiatry 2010; 18(7):643-51.
• Jones D, Hollingsworth K, Taylor R, Blamire A, Newton J. Abnormalities in pH Handling by Peripheral Muscle and Potential Regulation by the Autonomic Nervous System in Chronic Fatigue Syndrome. Journal of Internal Medicine 2010; 267(4):394-401.
• Jones DE, Hollingsworth KG, Fattakhova G, MacGowan GA, Taylor R, Blamire AM, et al. Impaired cardiovascular function in Primary Biliary Cirrhosis. Am J Physiol Gastrointest Liver Physiol 2010; .298(5):PG764-773.
• Palaniyappan L, Cousins DA. Brain Networks: Foundations and Futures in Bipolar Disorder Journal of Mental Health. 2010;19(2):157-67.
• Cousins DA, Brian Moore P, Watson S, Harrison L, Nicol Ferrier I, Young AH, et al. Pituitary volume and third ventricle width in euthymic patients with bipolar disorder. Psychoneuroendocrinology 2010; 35(7):1074-81. Epub 2010 Feb 19.
• Chalmers KH, De Luca E, Hogg NHM, Kenwright AM, Kuprov I, Parker D, Botta M, Wilson JI, Blamire, AM. Design Principles and Theory of Paramagnetic Fluorine Labelled Lanthanide Complexes as Probes for 19F Magnetic Resonance: a Proof of Concept Study. Eur J Chem 2010; 16: 134-148.
• Lim EL, Hollingsworth KG, Thelwall P, Taylor R. Measuring the acute effect of insulin infusion on ATP turnover rate in human skeletal muscle using phosphorus-31 magnetic resonance saturation transfer spectroscopy. NMR in Biomedicine 2010; 23:952-7.
• He J, Blamire AM. Application of variable-rate selective excitation pulses for spin labelling in perfusion MRI. Magn Reson Med. 2010;.63:842-847
  

Year 2009

• Cousins DA, Butts K, Young AH.  The role of dopamine in bipolar disorder.  Bipolar Disord 2009; 11: 787-806. 2009.
• Papakonstantinou L, Leslie P, Gray J, Chadwick T, Hudson M, Wilson JA. Laryngopharyngeal reflux: a prospective analysis of a 34 item symptom questionnaire. Clin Otolaryngol. 2009; 34(5):455-9.
• Watson R, Blamire AM, O’Brien JT. Magnetic resonance imaging in Lewy body dementias.  Dementia and Geriatric Cognitive Disorders 2009; 28:493-506
• Garrood P, Hollingsworth K, Eagle M, Aribisala B, Birchall D, Bushby K, et al. MR imaging in Duchenne muscular dystrophy: quantification of T1-weighted signal, contrast uptake and the effects of exercise. Journal of Magnetic Resonance Imaging 2009; 30(5):1130-8.
• Shepherd TM, Thelwall PE, Stanisz GJ, Blackband SJ. Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. Magnetic Resonance in Medicine 2009; 62: 26-34.
• Hollingsworth KG, Jones DE, Aribisala BS, Thelwall PE, Taylor R, Newton JL, Blamire AM . Globus pallidus magnetization transfer ratio, T(1) and T(2) in primary biliary cirrhosis: relationship with disease stage and age. J Magn Reson Imaging. 2009; 29(4):780-4.
• Stevenson EJ TP, Thomas K, Smith F, Brand-Miller J, Trenell MI. Dietary glycemic index influences lipid oxidation but not muscle or liver glycogen oxidation during exercise. Am J Physiol Endocrinol Metab 2009; 296(5):E1140-7. Epub 2009 Feb 17.
• Jovanovic A, Leverton E, Solanky B, Snaar JEM, Morris PEG, Taylor, R.  The second meal phenomenon is associated with enhanced muscle glycogen storage. Clin. Sci. 2009; 2;117(3):119-27
• Jovanovic A, Gerrard, J., Taylor, R. The second meal phenomenon in type 2 diabetes. Diabetes Care 2009 Jul;32(7):1199-201
• Hollingsworth KG, Newton JL, Blamire A, Taylor R, Jones DE. Loss of capacity to recover from acidosis on repeat exercise is strongly associated with fatigue in primary biliary cirrhosis (PBC) Hepatology 2009; 50(4):1504.
• Woodward JM, Priest AN, Hollingsworth KG, Lomas DJ. Clinical application of magnetic resonance spectroscopy of the liver in patients receiving long-term parenteral nutrition. J Parenter Enteral Nutr. 2009; 33:669-76.
  

Year 2008

• Blamire AM. The techonology of MRI - the next 10 years? British Journal of Radiology 2008; 81(968):601-17
• Hollingsworth KG, Newton JL, Taylor R, McDonald C, Palmer JM, Blamire AM, et al. Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis. Clin Gastroenterol Hepatol. 2008; 6(9):1041-8.
• Newton JL, Hollingsworth KG, Taylor R, El-Sharkawy AM, Khan ZU, Pearce R, et al. Cognitive impairment in primary biliary cirrhosis: symptom impact and potential etiology. Hepatology 2008; 48(2):541-9.
• Ravikumar B, Gerrard J, Man CD, Firbank MJ, Lane A, English PT, et al. Poglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content. Diabetes 2008; 57(9):2288-95.
• Sorensen L, Siddall PJ, Trenell MI, Yue DK. Differences in Metabolites in Pain-Processing Brain Regions in Patients With Diabetes and Painful Neuropathy. Diabetes Care 2008 May 1, 2008; 31(5):980-1.
• Taylor R. Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause. Diabetologia. 2008; 51(10):1781-9.
• Trenell MI, Hollingsworth KG, Lim EL, Taylor R. Increased daily walking improves lipid oxidation without changes in mitochondrial function in type 2 diabetes. Diabetes Care 2008; 31(8):1644-9.
• van der Poorten D, Milner K, Hui J, Hodge A, Trenell MI, Kench JG, et al. Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology. 2008; 48(2):449-57.
• Firbank, M.J., Barber R, Burton E.J, O’Brien JT. Validation of a fully automated hippocampal segmentation method on patients with dementia. Human Brain Mapping 2008; 29(12), 1442-1449. http://dx.doi.org/10.1002/hbm.20480
• Trenell MI, Stevenson E, Stockmann K, Brand-Miller J. Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise. British Journal of Nutrition. 2008 Feb;99(2):326-32. Epub 2007 Aug 15.
• Lim E, Trenell MI, Hollingsworth KG, Smith FE, Thelwell PE, Taylor R.  Is the sub-normal insulin stimulation of muscle ATP synthesis in type 2 diabetes always a consequence of low rates of muscle glycogen synthesis?   Diabetologia 2008; 51: 766
• Trenell, MI; Thelwall, P; Thomas, K; Stevenson, E.  Effect of high and low glycaemic index diets on skeletal muscle and liver substrate storage and utilisation during exercise.  Diabetologia 2008; 51: 248

Year 2007

• Thelwall PE. Detection of 17O-tagged phosphate by (31)P MRS: a method with potential for in vivo studies of phosphorus metabolism. Magnetic Resonance in Medicine. 2007; 57(6):1168-72.
• Zahra MA, Hollingsworth KG, Sala E, Lomas DJ, Tan LT. Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy. Lancet Oncology 2007; 8(1), 63-74.
• Blamire AM, Cader S, Lee M, Palace J, Matthews PM. Axonal damage in the spinal cord of multiple sclerosis patients detected by magnetic resonance spectroscopy. Magnetic Resonance in Medicine 2007; 58:880-5.
• Cousins DA and Allan H. Young. The armamentarium of treatments for bipolar disorder: a review of the literature. International Journal of Neuropsychopharmacology 2007; 10, 411–431. Copyright f 2006 CINP doi:10.1017/S1461145706007413
• Firbank MJ, Blamire AM, Krishnan MS, Teodorczuk A, English P, Gholkar A, et al. Atrophy is associated with posterior cingulate white matter disruption in dementia with Lewy bodies and Alzheimer's disease. Neuroimage. 2007; 36(1):1-7.
• Firbank MJ, Blamire AM, Krishnan MS, Teodorczuk A, English P, Gholkar A, et al. Diffusion tensor imaging in dementia with Lewy bodies and Alzheimer's disease. Psychiatry Research-Neuroimaging 2007; 155(2):135-45.
• Garrood P, Hollingsworth K, Thelwall P, Birchall D, Eagle M, Bushby K, et al. MRI in Duchenne muscular dystrophy: Quantification of fat infiltration and gadolinium uptake using whole-muscle regions of interest. Neuromuscular Disorders 2007; 17(9-10):816-7.
• Ravikumar B, Gerrard J, English PT, Firbank MJ, Taylor R. Combination therapy with PPARgamma and PPARalpha agonists in Type 2 diabetes improves glucose and lipid metabolism independent of changes in tissue triglyceride content. Diabetic Medicine 2007; 24:43.
• Jovanovic A, Gerrard J, Taylor R. Therapeutic application of the second meal effect in Type 2 diabetes. Diabetic Medicine 2007; 24:21.

Year 2006

• El-Badri SM, Cousins DA , Parker S, Ashton HC. McAllister VL, Ferrier IN, Moore PB. Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder. [Journal Article. Multicenter Study. Research Support, Non-U.S. Gov't] British Journal of Psychiatry 2006; 189:81-2. UI: 16816311