BBSRC Bioinformatics
and e-Science programme II
Grant #: BBS/B/16550 , January 2005-December 2007
The primary aim of the project is to capitalise on the development of GRID-based modelling and simulation resources such as BASIS by building a higher level computational GRID facility designed for integration of multiple post-genomic data resources. This facility, based on state-of-the-art Bayesian calibration techniques, will call upon GRID-based biological simulators for forward simulation whilst solving the inverse problems facilitated by data integration internally. Thus the project will provide a powerful new tool for the academic community that will enable inferences to be made about parameters and relationships within large network models of biochemical pathways and cell signalling systems.
A poster (PDF) is available which outlines the key ideas behind the CaliBayes project. This was produced for the BBSRC Bioinformatics and e-Science grantholders workshop in Edinburgh, November 2004.