ComparaGrid - enabling GRID technologies for comparative genomics

BBSRC Bioinformatics and e-Science programme II
Grant #: BBS/B/17158 , January 2005-December 2007

Outline

Integrating genomic data across species boundaries is critical to the successful exploitation of previous investment in this area. Systematic attempts to do this have thus far carried a single species focus e.g. annotating the genome of one species using functional data from a second. Because of the multiple potential views that could be applied to the combined dataset, a generalised "warehousing" approach will not succeed. We will develop a new GRID-based system to capture the details of relationships between genomic data either within or across species in a way that will enable complex ad-hoc queries to be run and demonstrate that the underlying raw data can be combined to draw maximum benefit from those data for all genomic communities.

Workpackage 4: Development of a Bayesian comparative genomics inference engine

This grant is a large and complex one, involving other investigators at Newcastle as well as other investigators from around the UK. The overall leader of the project is Dr Andy Law, head of bioinformatics at the Roslin Institute . The local (Newcastle) PI is Anil Wipat . This web page is for workpackage 4 only. For details regarding other aspects of the project, see the ComparaGRID home page.

Workpackage 4 Investigators

Website: www.comparagrid.org