Newcastle University

Introduction

My research interests are directed toward the application of nanotechnology for processing of biomaterials for tissue engineering and regenerative medicine. Key projects include:

• Design and development of scaffolds for musculoskeletal tissue repair and regeneration.
• Functionally gradient Collagen/HAp composite scaffold for osteochondral tissue engineering.
• Physical environment for the control of cellular behaviours of stem cells.
• Novel bioreactor system for osteochondral tissue engineering.
• Synthesis of nano-HAp/biopolymer composite.
• Rapid prototyping of collagen/HAp composite scaffold for bone tissue engineering.
• Control of biomolecular interactions at medical device surfaces.
• Surface functionalization of nanocarbon materials for drug delivery.
• Porous carbon surface modification for cleanning environment application.

• Osbeck S, Bradley RH, Liu C, Idriss H, Ward S. Effect of an ultraviolet/ozone treatment on the surface texture and functional groups on polyacrylonitrile carbon fibres. Carbon 2011, 49(13), 4322-4330.
• Liu C, Shen S, Han Z. Surface Wettability and Chemistry of Ozone Perfusion Processed Porous Collagen Scaffold. Journal of Bionic Engineering 2011, 8(3), 223-233.
• Cui N, Liu C, Yang W. XPS and AFM characterization of the self-assembled molecular monolayers of a 3-aminopropyltrimethoxysilane on silicon surface, and effects of substrate pretreatment by UV-irradiation. Surface and Interface Analysis 2011, 43(7), 1082-1088.
• Liu C, McKenna FM, Liang H, Johstone A, Abel EW. Enhanced cell colonization of collagen scaffold by UV/ozone surface processing. Tissue Engineering Part C: Methods 2010, 16(6), 1305-1314.
• Liu C, Han Z, Czernuszka J. Gradient collagen/nano-hydroxyapatite composite scaffold: development and characterization. Acta Biomaterialia 2009, 5(2), 661-669.
• Liu C. Biomimetic synthesis of collagen/nano-hydroxyapatite scaffold for tissue engineering. Journal of Bionic Engineering 2008, 5(S1), 1-8.
• Liu C, Meenan BJ. Effect of air plasma processing on the adsorption behaviour of bovine serum albumin on spin-coated PMMA surfaces. Journal of Bionic Engineering 2008, 5(3), 204-214.
• Liu C, Xia Z, Hulley PA, Triffitt JT, Czernuszka JT. Novel 3D collagen scaffolds fabricated by indirect printing technique for tissue engineering. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2008, 85B(2), 519-528.
• Liu C, Han Z, Hourd P, Czernuszka JT. On the process capability of the solid free-form fabrication: a case study of scaffold moulds for tissue engineering. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 2008, 222(3), 377-391.
• Cui NY, Liu C, Brown NMD, Meenan BJ. An Exploratory Study of the Effects of the Dielectric-barrier-discharge Surface Pre-treatment on the Self-assembly Processes of a (3-Aminopropyl) trimethoxysilane on Glass Substrates. Applied Surface Science 2007, 253(16), 6932-6938.
• Wahl DA, Sachlos E, Liu C, Czernuszka JT. Controlling the processing of collagen-hydroxyapatite scaffolds for bone tissue engineering. Journal of Materials Science: Materials in Medicine 2007, 18(2), 201-209.
• Liu C, Xia Z, Czernuszka JT. Design and development of three-dimensional scaffolds for tissue engineering. Chemical Engineering Research and Design 2007, 85(A7), 1051-1064.
• Liu C, Czernuszka JT. Development of biodegradable scaffolds for tissue engineering: a perspective on emerging technology. Materials Science and Technology 2007, 23(4), 379-392.
• Liu C, Sachlos E, Wahl DA, Han Z, Czernuszka JT. On the manufacturability of scaffold mould using a 3D printing technology. Rapid Prototyping Journal 2007, 13(3), 163-174.
• Liu C, Brown NMD, Meenan BJ. Dielectric barrier discharge (DBD) processing of PMMA surface: Optimization of operational parameters. Surface and Coatings Technology 2006, 201(6), 2341-2350.
• Liu C, Huhe A, Tao L. The coherent structure in backward-facing step flow and its role on sediment pickup. In: Sixth International Conference on Hydro-science and Engineering. 2004, Brisbane, Australia.
• Liu CZ, Green SM, Watkins ND, McCaskie AW. On the particle size and molecular weight distributions of clinical bone cements. Journal of Materials Science Letters 2003,22 16 1147-1150.
• Liu C, Green SM, Watkins ND, McCaskie AW. On the particle size and molecular weight distributions of clinical bone cements. Journal of Materials Science Letters 2003,22 9 709-712.
• Petrocelli R, Al Zahawi BAT, Liu C. Optimum switching sequence for matrix converters employing space vector modulation. In: Proceedings of the 36th Universities Power Engineering Conference, Session 4b. 2001, Swansea, UK: University of Wales.
• Liu C, Zahawi B, Petrocelli R. Single chip DSP implementation of three-phase matrix converter control. In: Proceedings of the 36th Universities Power Engineering Conference, Session 1b. 2001, Swansea, UK: University of Wales.