Diagnostic and Therapeutic Technologies Research Group

Theme Leader

Professor Calum McNeil

Major Research Themes

  • Development of biological sensors based on electrochemical and microelectromechanical (MEMS) systems for detection of infectious organisms.
  • Development of rapid, near-patient technology platforms for quantitative measurement of biochemical markers of disease and their application to home monitoring and management.
  • Development of multi-analyte sensor array platforms and optical nanoprobes to investigate the biochemical mechanisms underlying disease and cellular processes in order to better understand how, based on molecular pathways, disease progression varies between people so that interventions can have greater impact.


Guided by clinical need, our multi-disciplinary translational research can be applied to methods, technologies and materials to improve diagnostics and therapeutics. Research expertise in basic, applied and clinical science has resulted in significant translational funding being secured from Research Councils, the EC, industry, charities and venture-capital. By any research metric the Group is at the forefront of the field at an international level.

Key Collaborations

The D&TT Research Group has collaborative links within the Faculty of Medical Sciences and across all Faculties in the University. In addition, we have an extensive national and international network of collaborators in major Research Council and European Commission projects and with industry.

Developing Researchers

The support and development of researchers and succession planning are paramount to the work of the D&TT group. This ranges from support of MRes and PhD students to post-doctoral research associates and early-career academic staff. Many of the researchers trained in the D&TT group have gone on to academic positions in some of the UK's top Universities. Importantly, we also recognise the requirement for training and development of technical and administrative support staff who are vital to research success.

Impact and Engagement

The work of the D&TT group aims to improve knowledge of the molecular pathways that cause degenerative diseases. Our work has been highlighted in a number of public engagement and outreach activities including producing news items and videos aimed at public education of the D&TT vision of successful outcomes of collaborative multi-disciplinary research and also using social media to highlight achievements. See:

d-LIVER on Euronews TV: Video feature and report are available at the Euronews-Futuris website http://www.euronews.com/2014/11/03/longer-life-for-damaged-livers/

Top Story on EC CORDIS news site: http://cordis.europa.eu/results/rcn/150356_en.html



Related websites:

Staff List


Professor Mark Birch-Machin
(1) Associate Dean of Business Development and Commercial interface (2) Professor of Molecular Dermatology (3) Deputy Degree Programme Director MRes (Biotechnology) (4) Co-Founder:Genesis Genomics (now Mitomics) Inc (5) Co-Founder PB Bioscience Ltd

Dr Barry Gallacher
Reader in Engineering Dynamics

Professor Colin Harwood
Professor of Molecular Microbiology

Dr John Hedley
Senior Lecturer

Dr Mark Hudson
Honorary Clinical Senior Lecturer

Professor David Jones
Professor of Liver Immunology

Dr Neil Keegan
Senior Lecturer

Dr Philip Manning

Dr Stuart McCracken
Clinical Fellow and Honorary Consultant in Urological Surgery

Professor Calum McNeil
Professor of Biological Sensor Systems

Dr James Orr

Professor Naeem Soomro
Honorary Professor of Urology

Professor Anil Wipat
Professor of Integrative Bioinformatics

Professor Matthew Wright
Professor of Toxicology

National Health Service (NHS) & Public Health England (PHE) Staff

  • Dr Dermot Neely - NHS
  • Dr Andy Sails - PHE
  • Prof John Magee - PHE

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