Liver
Newcastle Liver Research Group
Theme Leader
Professor Derek Mann (Head of Research Group) and Dr Quentin M. Anstee (Clinical Research Lead)
Major Research Themes
The Newcastle Liver Research Group maintains critical mass to support on-going research in the field of hepatology, genetics and liver biology and provides a forum to support bi-directional translational research and collaboration.
Expertise
With a membership comprising basic-scientists and clinician-scientists, the liver research group provides a forum for 'cross-pollination' of ideas between related disciplines. This grouping has already successfully translated a number of basic research projects 'to the bedside' where clinical trials are on-going examining novel anti-fibrotic approaches to slow fibrosis in fatty liver disease.
Members of the group are advancing research in the fields of:
- non-alcoholic fatty liver disease (NAFLD)
- primary biliary cirrhosis (PBC)
- alcoholic liver disease
- hepatocellular carcinoma (HCC)
- genetic and epigenetic modifiers of liver disease severity (in patient cohorts and animal models)
- tissue fibrosis
Within these areas we are leaders in several national and international clinical research collaborations including the H2020 funded 'Elucidating Pathways of Steatohepatitis' (EPOS) consortium, ‘UK Genetics of Liver Disease’ (UK GoLD) consortium and the ‘UK-PBC’ consortium.
Professor Quentin Anstee
Professor of Experimental Hepatology & Consultant Hepatologist
Email: quentin.anstee@ncl.ac.uk
Telephone: +44 (0) 191 208 7012
Professor Alastair Burt
Associate Clinical Researcher
Email: alastair.burt@ncl.ac.uk
Telephone: +44 (0) 191 282 0700
Professor Ann Daly
Professor of Pharmacogenetics and Associate Dean for Internationalisation (Faculty of Medical Sciences)
Email: a.k.daly@ncl.ac.uk
Telephone: +44 (0) 191 208 7031
Professor Chris Day
Vice-Chancellor & President
Email: chris.day@ncl.ac.uk
Telephone: +44 (0) 191 208 6064
Professor David Jones
Professor of Liver Immunology
Email: david.jones@ncl.ac.uk
Telephone: +44 (0) 191 208 7572
Professor John Kirby
Dean of PG Studies
Email: john.kirby@ncl.ac.uk
Telephone: +44 (0) 191 208 7057
Professor Derek Manas
Hon Clin Prof of Transplantation
Professor Jelena Mann
Professor of Epigenetics
Email: jelena.mann@ncl.ac.uk
Telephone: +44 (0) 191 208 5902
Professor Derek Mann
Dean of Research & Innovation (Non-Clin)
Email: derek.mann@ncl.ac.uk
Telephone: +44 (0) 191 208 3851
Professor Fiona Oakley
Prof of Fibrosis Biology
Email: fiona.oakley@ncl.ac.uk
Telephone: +44 (0) 191 208 3852
Professor Helen Reeves
Professor of Liver Cancer & Honorary Consultant Gastroenterologist
Email: helen.reeves@ncl.ac.uk
Telephone: +44 (0) 191 208 4423
Professor Matthew Wright
Professor of Toxicology
Email: matthew.wright@ncl.ac.uk
Telephone: +44 (0) 191 208 7094