Faculty of Medical Sciences

Liver

Newcastle Liver Research Group

The group is internationally recognised in the field of liver research.

Theme Leader

Professor Derek Mann (Head of Research Group) and Dr Quentin M. Anstee (Clinical Research Lead)

Major Research Themes

The Newcastle Liver Research Group maintains critical mass to support on-going research in the field of hepatology, genetics and liver biology and provides a forum to support bi-directional translational research and collaboration.

Expertise

With a membership comprising basic-scientists and clinician-scientists, the liver research group provides a forum for 'cross-pollination' of ideas between related disciplines. This grouping has already successfully translated a number of basic research projects 'to the bedside' where clinical trials are on-going examining novel anti-fibrotic approaches to slow fibrosis in fatty liver disease.

Members of the group are advancing research in the fields of:

  • non-alcoholic fatty liver disease (NAFLD)
  • primary biliary cirrhosis (PBC)
  • alcoholic liver disease
  • hepatocellular carcinoma (HCC)
  • genetic and epigenetic modifiers of liver disease severity (in patient cohorts and animal models)
  • tissue fibrosis

Within these areas we are leaders in several national and international clinical research collaborations including the ‘UK Genetics of Liver Disease’ (UK GoLD) consortium, ‘Fatty Liver Inhibition of Progression’ (FLIP) consortium and the ‘UK-PBC’ consortium.

Staff List

Professor Quentin Anstee
Professor of Experimental Hepatology & Consultant Hepatologist

Email:
Telephone: +44 (0) 191 208 7012


Telephone: +44 (0) 191 213 7208

Professor Alastair Burt
Associate Clinical Researcher

Email:
Telephone: +44 (0) 191 282 0700

Professor Ann Daly
Professor of Pharmacogenetics and Associate Dean for Internationalisation (Faculty of Medical Sciences)

Email:
Telephone: +44 (0) 191 208 7031

Professor Chris Day
PVC of Medical Sciences

Email:
Telephone: +44 (0) 191 208 7003

Dr Peter Donaldson
Senior Lecturer

Email:
Telephone: +44 (0) 191 208 8868

Professor David Jones
Professor of Liver Immunology

Email:
Telephone: +44 (0) 191 208 7572

Professor John Kirby
Dean of PG Studies

Email:
Telephone: +44 (0) 191 208 7057

Professor Derek Manas
Hon Clin Prof of Transplantation

Dr Jelena Mann
Reader in Epigenetics

Email:
Telephone: +44 (0) 191 208 5902

Professor Derek Mann
Prof of Hepatology

Email:
Telephone: +44 (0) 191 208 3851

Professor Fiona Oakley
Prof of Fibrosis Biology

Email:
Telephone: +44 (0) 191 208 3852

Dr Helen Reeves
Senior Lecturer & Honorary Consultant Gastroenterologist at Newcastle Hospitals NHS Foundation Trust

Email:
Telephone: +44 (0) 191 208 4423

Email:
Telephone: +44 (0) 191 208 7629

Professor Matthew Wright
Professor of Toxicology

Email:
Telephone: +44 (0) 191 208 7094