Faculty of Medical Sciences

Staff Profile

Professor Fiona Oakley

Prof of Fibrosis Biology

Background

Roles and Responsibilities

Academic lead on the in vivo imaging system (IVIS) http://www.ncl.ac.uk/bioimaging/equipment/ivis/

Qualifications

1994-1997 – BSc Physiology and Biochemistry, university of Southampton
December 2000 - PhD awarded, University of Southampton

Previous Positions

1/10/05-31/08/06 School of Medicine Career Track Award, University of Southampton
02/04/03-30/08/05 Post doctoral scientist Wellcome Trust, University of Southampton
01/07/00- 31/03/03 Post doctoral scientist MRC, University of Southampton

Memberships

British Association for the Study of Liver disease (BASL), Basic Science committee member.

European Association for the Study of Liver disease (EASL).

Honours and Awards

Dame Sheila Sherlock Young Investigator Award 2006.

Research

Research Interests

Current research projects include investigating the discrete biological functions of the c-Rel subnit of NF-kB subunits in heart and skin physiology and disease. Other work involves understanding how NF-kappaB and serotonin signaling regulates liver inflammation, fibrosis and regeneration. 

Postgraduate Supervision

currently supervise two postgraduate students

Funding

May 2010. Medical Research Council New Investigator Research Grant (NIRG). RelA Serine 536 Phosphorylation as a Selective Therapeutic Target in Fibrotic Disease. 

Awarded May 2008: Wellcome Trust, the role of hepatic myofibroblasts in hepatic injury and regeneration. PI Matthew Wright, co-applicants Derek Mann, Fiona Oakley and Alastair Burt.

Awarded March 2008: MRC Mres/PhD Studentship - NF-Kappaβ Signalling is a Critical Regulator of Skin Ageing – Do Manipulating Specific Components of NF-kappaβ Signalling Rejuvenate Skin? Fiona Oakley, Derek Mann, Nick Reynolds, Mark Birch-Machin.

Awarded November 2007, MRC research grant: A functional dissection of the serotonin system in liver disease. 2 years. PI Derek Mann, co-applicants Fiona Oakley and Matthew Wright.

Gerald kerkut charitable Trust funded PhD studentship. The role of nfkb1 in cardiovascular physiology. Co-applicants Prof. Derek Mann (Newcastle, ICM) and Dr Paul Townsend (University of Southampton)

Teaching

Undergraduate Teaching

Supervise undergraduate lab projects

Postgraduate Teaching

Supervising three PhD students

Supervising two masters students

Publications