Faculty of Medical Sciences

Staff Profile

Dr Louise Sutcliffe

Research Associate

Background

Research Experience

My background is in clinical trials and clinical research, and I have worked across this area in academia, the NHS, and the private sector in pharmaceutical/biopharmaceutical companies and contract research organisations. I am currently in the Institute of Neuroscience at Newcastle managing clinical trials for the Stroke Research Group. Previously I was a research associate with Helen Phillips and Judith Goodship's groups working on studies of the genetics of congenital heart disease and heart development in the Institute of Genetic Medicine. Other previous experience includes recruiting heart and kidney transplant patients for the Institute of Transplantation Biobank, and knee replacement patients in the Freeman Hospital, and as technical administrator managing SOPs and regulatory documentation for a clinical trials pathology laboratory at a CRO. 

Qualifications

PhD Biology Durham University CASE Studentship with Lonza Biologics 2008-2012 "Chemical genetic dissection of efferent IRE1a signalling"    - Investigating protein folding mechanisms as a way to improve biopharmaceutical yields and quality. http://etheses.dur.ac.uk/5943/

BSc Hons Pharmacology with Industrial Experience 2001-2005 University of Manchester

Publications

See publications tab,

Acknowledged for patient recruitment/tissue collection in:

 Dixon D, Coates J, del Carpio Pons A, Horabin J, Walker A, Abdul N, Kalson NS, Brewster NT, Weir DJ, Deehan DJ, Mann DA, Borthwick LA. A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty. Sci Rep. 2015 Nov 10;5:16466.

 Parry SW, Deary V, Finch T, Bamford C, Sabin N, McMeekin P, O'Brien J, Caldwell A, Steen N, Whitney SL, Macdonald C, McColl E. The STRIDE (Strategies to Increase confidence, InDependence and Energy) study: cognitive behavioural therapy-based intervention to reduce fear of falling in older fallers living in the community - study protocol for a randomised controlled trial. Trials. 2014 Jun 6;15:210. doi: 10.1186/1745-6215-15-210. PubMed PMID: 24906406; PubMed Central PMCID: PMC4059076.

Research

I am currently working in the Stroke Research Group on the PASTA (https://research.ncl.ac.uk/pasta/) and WAVES trials. 

Publications