Faculty of Medical Sciences

Staff Profile

Professor Sally Marshall

Professor of Diabetes

Research

Research Interests

My major interest is in diabetic nephropathy - genetics, cellular biology, natural history, links to cardiovascular disease and management. Current projects include:
1. role of polymorphisms of cytoskeletal proteins in the development of nephropathy, using the Warren 3 DNA repository for type 1 diabetes
2. investigations into the increased thrombogenicity seen in diabetes, using the Baudimon chamber to assess ex vivo thrombogenicity and the response to antiplatelet therapy
3. studies relating expression of the pro-thrombotic phospholipid phosphatidylserine (PS) on the outer membrane of platelets to vascular risk. In vitro work explores the mechanisms stimulating expression of PS and differences between non-diabetic and diabetic patients and patients with and without renal disease.

Publications