ACE2034 : Introduction to Immunology and Toxicology
- Offered for Year: 2017/18
- Module Leader(s): Professor Ilias Kyriazakis
- Other Staff: Dr Helen Mason
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
|Semester 2 Credit Value:||10|
To introduce the students to the basic concepts and processes involved in immunology and toxicology in mammals. This knowledge of the fate of foreign compounds within the body, innate and adapted immune mechanisms, immune cells, and deregulation (allergies, auto-immune diseases, cancer) will support students further studies of human and animal health and its links to disease and nutrition in their further study. Students will also develop knowledge of the use of serological tests to assess infection status and risk assessment for potential toxins.
Outline Of Syllabus
The syllabus will cover the following topics involving lectures from University staff and external speakers.
- Fate of foreign compounds within the body
- Dose-response relationships
- Types of toxic responses especially to nutritional challenges and natural toxins (animal, plant, fungal and microbial)
- Natural defences
- Innate/Adaptive immunity
- Cellular and humoral immunity
- Production and use of antibodies
- Communication within the immune system
- Serological tests (ELISA, IFAT, Western blotting, Electron microscopy)
- Auto-immune diseases
- Nutrition and the immune system
|Guided Independent Study||Assessment preparation and completion||1||10:30||10:30||Revision for and completion of Semester 2 examination|
|Scheduled Learning And Teaching Activities||Lecture||18||1:00||18:00||N/A|
|Guided Independent Study||Assessment preparation and completion||1||10:00||10:00||Preparation for ELISA report|
|Guided Independent Study||Assessment preparation and completion||1||10:00||10:00||Preparation of essay|
|Scheduled Learning And Teaching Activities||Small group teaching||2||2:00||4:00||Focused groups assessing practical problems|
|Scheduled Learning And Teaching Activities||Workshops||1||2:00||2:00||Discussion of feedback from essays and of practical issues (toxicology)|
|Guided Independent Study||Independent study||1||25:30||25:30||Literature search and reading beyond the course material|
|Guided Independent Study||Independent study||1||20:00||20:00||Compilation of notes and follow up after lectures|
Teaching Rationale And Relationship
Lectures and small group problem-based teaching allows the presentation of clear background information, extension of this materials by use of examples and identification of further reading to allow students to develop a substantial knowledge base on immunology and toxicology to meet all the Module's knowledge outcomes
The workshop (toxicology) allows for discussion of problems / issues which will require application of materials covered in class.
The small group teaching allows for the development of skills in practical immunological techniques and the interpretation of serological data, in particular the ability to handle and manipulate relevant diagnostic test data to improve numerical skills and adopt analytical, quantitative approaches to problems.
The format of resits will be determined by the Board of Examiners
|Written Examination||90||2||A||60||Essay type questions, answer 3 out of 5 questions. 2 questions for each topic area and one integrating question|
|Essay||2||M||20||Essay, dose-response relationships to toxins, 1000 words|
|Practical/lab report||2||M||20||ELISA Report up to 3 pages|
Assessment Rationale And Relationship
The examination allows a test of all the knowledge outcomes and assesses student's ability to integrate material as well as recall of key content of the module and relevant information from other sources.
The in-course assessment provides students with feedback on the development of their understanding and their ability to write technical reports clearly and support findings with reference to appropriate literature
The ELISA report specifically tests students ability to apply and interpret serological tests to measure immune response
The essay specifically focus on dose-response relationships to a range of toxins and their limitations.
- Reading List Website : rlo.ncl.ac.uk