BGM1004 : Genetics
- Offered for Year: 2017/18
- Module Leader(s): Dr Catherine Meplan
- Lecturer: Professor Brian Morgan, Prof. Sir John Burn, Dr Simon Whitehall, Professor T. Martin Embley, Dr Jeremy Brown, Professor Deborah Henderson, Professor Colin Harwood
- Other Staff: Professor David Lydall, Professor Susan Lindsay, Dr Simon Bamforth, Dr Helen Phillips, Dr Carys Watts
- Owning School: Biomedical Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||15|
The aims of this module are to;
• introduce the fundamental principles of Mendelian genetics, population genetics and current concepts of molecular genetics applied to bacteria and eukaryotes required by all bioscience students;
• provide an opportunity for students to interpret genetic information and work through problems in seminars, and relate their knowledge of genetics to laboratory classes in associated modules;
• increase awareness of human genetic diseases and the application of analytical techniques to their diagnosis and potential treatment.
• introduce some of the molecular and genetic techniques being used in the postgenomic
era of genetics as well as recent advances in genetic analysis including the use of model organisms
• provide sufficient knowledge and understanding of the subject to inform student choice to study genetics in phase 2 of the degree.
Outline Of Syllabus
Lectures and seminars will cover the following topics:
• Evolutionary genetics: prebiotic chemistry; ribozymes as molecular fossils; molecular phylogenetics and population genetics.
• Molecular genetics: introduction to bacterial genetics; structure of the bacterial chromosome; comparative genomics; DNA replication and fidelity.
• Eukaryote and Human Genetics: model eukaryotic organisms for genetic analysis; organization of eukaryotic genomes; mitosis and meiosis; sex determination, eukaryotic genes and transcripts; inheritance; recombination & genetic diversity; genome evolution & multigene families.
• Developmental and Medical Genetics: genetic analysis of human disease; modern methods of mapping susceptibility alleles; yeast as a human disease model; clinical genetics of complex diseases; ethics in Genetics
|Guided Independent Study||Assessment preparation and completion||1||1:00||1:00||Formative class tests|
|Scheduled Learning And Teaching Activities||Lecture||26||1:00||26:00||N/A|
|Scheduled Learning And Teaching Activities||Small group teaching||4||1:00||4:00||Seminars|
|Guided Independent Study||Independent study||1||119:00||119:00||N/A|
Teaching Rationale And Relationship
1. Lectures will define the scope of the course and communicate basic knowledge as a basis for further study.
2. Seminars will encourage students to develop their understanding of the subject and interpersonal communication skills. They provide an opportunity for students to ask questions and exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication & team working.
3. Private study is used for self-directed learning and includes: reading lecture notes and texts; preparation for seminars; using learning resources on the Web. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.
The format of resits will be determined by the Board of Examiners
|Written Examination||90||1||A||100||EMI format: 25-30 questions|
|Computer assessment||1||M||A mid-semester EMI (formative) 25-30 questions will be provided to students under exam conditions.|
Assessment Rationale And Relationship
The end of semester examination assesses knowledge and understanding of the course material. The formative EMI questions will help students assess their knowledge and understanding of course material as well as familiarise students with the format of an EMI exam.
FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submission dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.
The form of assessment will not vary from the original.