BMS2012 : Clinical Immunology and Viral Pathogens
- Offered for Year: 2017/18
- Module Leader(s): Dr Debra Bevitt
- Lecturer: Professor John Kirby, Dr Simon Whitehall, Professor Jane Calvert, Dr Robert Yeo, Dr Beth Lawry, Dr Christopher Bacon, Dr Andrew Gennery, Professor Robert Hirt
- Owning School: Biomedical Sciences
- Teaching Location: Newcastle City Campus
|Semester 2 Credit Value:||20|
• To develop an appreciation of the part played by the immune system in a range of human diseases
•To build upon the students’ knowledge of basic virology and develop an understanding of the biology of pathogenic viruses
Outline Of Syllabus
Clinical Immunology Strand:
The module considers the role of the immune system in human disease. The first part of the module considers immunity in the context of infectious disease with particular reference to inflammation and immunodeficiency. The second part of the module considers how immune responses can cause disease with reference to allergic disease, autoimmunity, cancers of the immune system and transplantation. Finally the module describes the diagnostic techniques currently used in clinical immunology, immunosuppressive drugs and the potential of immunomodulation and immunotherapy in the treatment of a number of conditions.
Strand B (Viral Pathogens) considers the ways in which viruses cause disease. It examines the mechanisms by which viruses enter host cells, replicate within them and are finally released and transmitted from man to man and from animals to man. The host response to viral infection is described and the outcomes, including full recovery, acute infection, chronic infection, latent infection and death are considered. Specific examples, including measles virus, hepatitis B virus, herpes viruses and Ebola virus are described. The role of viruses in development of some cancers is discussed, examining the role of human papilloma virus in cervical cancer in particular. Finally retroviruses are discussed, including HIV and retroviruses used in gene therapy.
|Scheduled Learning And Teaching Activities||Lecture||2||1:00||2:00||Seminar - full module cohort in attendance|
|Scheduled Learning And Teaching Activities||Lecture||28||1:00||28:00||N/A|
|Scheduled Learning And Teaching Activities||Small group teaching||1||2:00||2:00||Scientific paper interpretation workshop|
|Scheduled Learning And Teaching Activities||Small group teaching||1||2:00||2:00||Poster Presentation|
|Guided Independent Study||Independent study||1||166:00||166:00||N/A|
Teaching Rationale And Relationship
Lectures will provide students with key information and guidance for additional reading.
Poster presentation and paper interpretation workshop develop interpersonal communication, increase understanding of lecture material and primary literature by discussion with peers and teachers and help prepare students for final exam. Private study will allow students to extend and reinforce their knowledge and understanding through reading of text books, journal articles and use of other recommended resources (eg online).
The format of resits will be determined by the Board of Examiners
|Written Examination||120||2||A||80||Unseen – 50% EMI and 50% scientific paper interpretation exercise.|
|Prof skill assessmnt||2||M||10||Poster Presentation (10 mins) - team present a poster summarising experimental data from a scientific research paper|
|Prob solv exercises||2||M||10||Guided interpretation of a primary research paper (500-1000)|
Assessment Rationale And Relationship
The EMI section of the examination will assess the students breadth of knowledge and understanding; the scientific paper interpretation section of the examination will assess the students ability to use their knowledge and understanding of the topics to data presented in a scientific research paper.
The poster presentation assesses information literacy, computer literacy, ability to interpret scientific papers, planning and organisation skills, group working skills and oral presentation skills. The scientific paper interpretation exercise assesses ability to interpret data presented in a scientific research paper and will prepare students for the scientific paper interpretation element of the examination.
- Reading List Website : rlo.ncl.ac.uk