CMB2002 : Cell and Molecular Biosciences
- Offered for Year: 2017/18
- Module Leader(s): Dr Michael Gray
- Lecturer: Dr Simon Whitehall, Professor Colin Harwood, Dr Nick Watkins, Dr Anjam Khan, Professor Neil Perkins, Dr Timothy Cheek, Professor Loranne Agius, Prof. Dianne Ford
- Owning School: Biomedical Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||20|
The Aims are that students:
• To develop knowledge and understanding of some of the most important means by which animal and bacterial cells sense and respond to their environment and how they communicate with each other, including the cellular and molecular mechanisms used to interpret the signals they receive.
• To understand the role of cell signalling in human disease.
• To understand the concept of a stem cell.
• To understand the mechanisms whereby cell numbers in the body are regulated including increases by cell division and decreases by apoptosis.
• To develop knowledge and understanding of the mechanisms by which eukaryotes regulate gene expression.
Outline Of Syllabus
This module presents two topics central to our understanding of life processes: cell signalling and regulation of gene expression.
The cell signalling topic describes how both prokaryotic and eukaryotic cells communicate with each other by the means of chemical 'signals'. In additional it discusses the receptors in the cell surface that these chemicals bind to and the cascade of reactions that employ intracellular messengers, that are initiated after the chemical interacts with the receptor.
The regulation of gene expression strand describes the mechanisms that control gene expression.
The lectures will introduce the basics of gene structure and transcription in prokaryotes and eukaryotes; the role of chromatins, promoters, polymerases, operons, transcription factors and the regulation of their interaction with DNA.In addition they will describe how regulation of mRNA stability and translation can contribute to control of gene expression.
|Guided Independent Study||Assessment preparation and completion||2||1:00||2:00||Class Tests|
|Scheduled Learning And Teaching Activities||Lecture||30||1:00||30:00|
|Scheduled Learning And Teaching Activities||Small group teaching||1||1:00||1:00||Seminars|
|Guided Independent Study||Independent study||167||1:00||167:00||Private study|
Teaching Rationale And Relationship
Lectures are used to impart information in a concise manner, to highlight areas of importance and to interrelate with directed reading and self-directed study. The seminars are used for developing skills of data interpretation, problem-solving and information retrieval. Private study is used for self-directed learning including further reading and preparation for examinations.
The format of resits will be determined by the Board of Examiners
|Written exercise||1||M||5||Data Interpretation|
|Prob solv exercises||1||M||5||EMI|
Assessment Rationale And Relationship
The examination tests knowledge and understanding.
The in course assessments are both formative and summative. The in-course EMI tests knowledge and understanding and provides students with information about their progress. The data interpretation tests the ability to apply knowledge and understanding to solve problems. The timed essay tests knowledge, the ability to retrieve information and use the knowledge and information to formulate scientific ideas and arguments and aims to prepare students for essay-based examinations.
FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.
The form of assessment will not vary from the original.
- Reading List Website : rlo.ncl.ac.uk