PSC3013 : Physiology of the Gastrointestinal Tract 2
- Offered for Year: 2017/18
- Module Leader(s): Professor David Thwaites
- Lecturer: Professor Jeffrey Pearson, Dr Judith Hall, Professor Brendan Kenny, Professor Barry Hirst
- Owning School: Biomedical Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||15|
This pair of modules (PSC3011 and PSC3013) on the Physiology of the Gastrointestinal Tract will give a broad grounding in many areas of gut function. The PSC3013 module (Physiology of the Gastrointestinal Tract 2) is designed to develop knowledge and advance understanding of the physiology and cellular physiology of:
• neurohormonal control of gastric function
• parietal cell function and gastric acid secretion
• mucosal immunity and defence
• gastric mucosal protection
Outline Of Syllabus
The module provides an introduction to the physiological, pathophysiological and pharmacological control of gastric acid secretion. The three phases (cephalic, gastric, intestinal) of the physiological control of gastric acid secretion will be explored in detail by an in-depth investigation of past and current landmark observations. The molecular and cellular mechanisms of control and function of the gastric parietal cell will be explored. The roles of specialised intestinal antigen sampling M cells and antimicrobial peptides in mucosal immunity and defence will be considered. The strategies used by bacteria to modify gastrointestinal tract function will be examined by comparison of pathogenic and non-pathogenic bacteria. The physiology of gastrointestinal mucosal protection will be described and the roles of aggressive and defensive factors in the physiological and pathophysiological control of gastrointestinal barrier function discussed.
|Guided Independent Study||Assessment preparation and completion||1||15:00||15:00||Practical/lab report preparation|
|Scheduled Learning And Teaching Activities||Lecture||20||1:00||20:00||Lectures|
|Guided Independent Study||Assessment preparation and completion||1||106:00||106:00||Lecture review, extra reading, MCQ revision|
|Scheduled Learning And Teaching Activities||Lecture||1||1:00||1:00||Group feedback seminar (MCQ exam)|
|Guided Independent Study||Assessment preparation and completion||1||1:00||1:00||In-course MCQ exam|
|Scheduled Learning And Teaching Activities||Practical||1||7:00||7:00||Practical|
Teaching Rationale And Relationship
Lectures are used to convey new information, core scientific material and key concepts in a concise manner (K1-K5, S1). Lectures are used to direct students towards important original sources of information in the study guides to provide a framework for guided independent study (K1-K5, S1-S2). Lectures are used to aid the development of an understanding of current research and the experimental basis of key concepts and core knowledge (K2-K5, S1-S2). The practical provides laboratory experience and a practical demonstration to support the core material (K5, S2-S3).
The group feedback session provides critical feedback on the assessed in-course MCQ exam and provides an opportunity to increase understanding by reflection and discussion (K1-K2, S1-S2).
The format of resits will be determined by the Board of Examiners
|Written Examination||90||2||A||80||Two questions to be answered, one from each of two sections, with choice from two within each section.|
|Module Code||Module Title||Semester||Comment|
|PSC3011||Physiology of the Gastrointestinal Tract 1||2||N/A|
|Practical/lab report||1||M||10||Laboratory report on the mucosal protection practical includes data analysis and questions associated with the practical material|
|Prob solv exercises||1||M||10||In-course MCQ exam (60 mins)|
Assessment Rationale And Relationship
The written examination tests core knowledge and understanding of the subject under time-constraint conditions (K1-K5, S1-S2). The in-course MCQ exam promotes revision and provides the opportunity to consolidate knowledge and identify areas of weakness in learning and understanding (K1-K5, S1-S2). The practical and written report test the capacity to perform laboratory work, problem solving and data interpretation (S1-S3). The practical report is prepared as a group report and thus encourages the development of team work and written scientific communication skills (S1-S3).
FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.
- Reading List Website : rlo.ncl.ac.uk